Curated Macro

[Curated Macro @CuratedMacro]

All complex systems move in rhythm.

Markets are no different.

Groove = regime
Syncopation = hidden stress
Fills = volatility
Tempo shift = regime change
Silence = optionality

Most people trade fills.
Edge lives in reading the rhythm.

[The Vigilant Fox 🦊 @VigilantFox]

Joe Rogan yells "Holy sh*t!" after Harvard professor of genetics David Sinclair says sudden blindness has DOUBLED because of GLP-1 drugs.

Then Rogan pulls up the data himself — and what he reads out loud is even worse.

SINCLAIR: "Glaucoma and also sudden blindness. It's called NAION, which is now twice as more prevalent because of the GLP-1 drugs."

ROGAN: "Really?!"

SINCLAIR: "It's not well known. Obviously companies don't want to talk about it. But yes, sudden blindness has doubled, seemingly because of these meds."

ROGAN: "Holy shit!"

SINCLAIR: "Careful."

ROGAN: "Sudden blindness has doubled because of GLP-1s?"

SINCLAIR: "Due to NAION, which is like a stroke in your eye, and then your other eye can go. Which is pretty scary. And there's nothing you can do about it. Hopefully our drug does work for those people."

ROGAN: "And, obviously correlation does not equal causation, but it seems to be."

SINCLAIR: "Yeah, there's a scientist at Harvard. You could look up his work. Joe Rizzo. It looks like it's repeatable across the planet."

ROGAN: "Wow, that's terrible. Terrible because there's so many people out there that are just telling everyone they should get on GLP-1s… Like online podcasters saying, 'Everyone should get on GLP-1s… It's going to transform society.' I'm like, 'We just started taking these! The f*ck are you saying?!'"

SINCLAIR: "Yeah, it's not risk free. Same with ED drugs."

ROGAN: "Here goes. Recent studies suggest that a potential risk — rare link between GLP-1 receptor agonist medications such as Ozempic, Wegovy, blah, blah, blah, and… an eye stroke [that] can cause sudden, painless loss of vision in one eye, while absolute risk remains very low."

ROGAN: "Well, very low is like… What does that mean?"

SINCLAIR: "One in 10,000 people."

ROGAN: "One in 10,000?"

SINCLAIR: "Oh no. Total of 10,000."

ROGAN: "Oh, total of 10,000 so far? How many people are taking this stuff?"

[Rogan continues reading]

"The drugs were 68.6 times more likely to develop this [eye stroke] and 8 times more likely to develop… diabetic retinopathy."

ROGAN: "Oh, my God. Then… Wow."

ROGAN: "Yeah, man. These things are just — they're just rolling out…"

[Black Hole @konstructivizm]

A side of our planet that goes unnoticed by many: the vast expanses of the Pacific Ocean.

[Math Pulse @themathpulse]

Everything we call real is made of things that cannot be regarded as real.

If quantum mechanics hasn't profoundly shocked you, you haven't understood it yet.

— Niels Bohr

[Sal the Agorist @SallyMayweather]

Delta 8 THC is now a felony in Texas.

DUI isn't a felony until your 3rd DUI in Texas.

Republicans are incapable of competent government.

[Elon Musk @elonmusk]

@davidasinclair Release a cure already then 😂

What’s holding you back?

[Matheorems @matheorems]

A fractal spirograph formed by nested circles that roll around each other recursively.

A pen fixed to the smallest circle tra
ces a self-similar path, gradually building intricate branching arms into a symmetric multi-pointed star.

[KanekoaTheGreat @KanekoaTheGreat]

One of the greatest mysteries of COVID-19: Where did the flu go in 2020 and 2021?

[Amazing Things @amazingthings_]

An incredible wind-powered drummer made entirely from scrap metal

[MindBranches @MindBranches]

@trq212 Article Summary: The new rules of context engineering for Claude 5 models

[Night Sky Now @NightSkyNow]

This is how the Solar System travels around the center of the galaxy, taking 225 million to 250 million years for a full orbit.

[Massimo @Rainmaker1973]

The James Webb Space Telescope has done it again: revealing a breathtaking structure now dubbed the “Cosmic Vine”: a string of 20 galaxies stretching across a staggering 13 million light-years!

What makes this discovery so shocking? This colossal formation dates back nearly 11 billion years, forming just 3 billion years after the Big Bang, a time when galaxies were thought to still be forming in isolated clumps. Instead, JWST captured a massive, organized structure linking galaxies together much earlier than expected.

[image: artist's impression]

[Polymarket Money @PolymarketMoney]

BREAKING: Elon Musk acquires Jacksonville power company APR Energy in a deal valued at more than $1,000,000,000.00.

[ₕₐₘₚₜₒₙ @hamptonism]

You’ll learn more about Ai watching this 8 minute video, than you will at studying in the world’s top institutions.

[Polymarket @Polymarket]

JUST IN: Warren Buffett ends all donations to the Gates Foundation after new revelations about Bill Gates’ ties to Jeffrey Epstein.

[The White House @WhiteHouse]

President Trump looks on as @Freedom250GP @IndyCar crew performs a flawless pit stop at the White House! 🇺🇸🏎️

[Leading Report @LeadingReport]

JUST IN: U.S. LAUNCHES STRIKES AGAINST IRAN.

[Nicholas J. Fuentes @NickJFuentes]

Tucker’s nephew, Charles, works for Palantir.

Tucker’s son, Buckley, worked for JD Vance.

Tucker’s father, Dick, worked for the CIA.

Tucker’s friend, Joe Kent, was a CIA officer.

[Chief Nerd @TheChiefNerd]

ROGAN: “People are pointing out that right now it's one of the rare times where no rap music is on the charts. And they're saying, how does this coincide with USAID? Was USAID actively promoting rap music?” 🤔

[Jafet Huipet @J4feT_25]

México, el país que:

"No estaba en condiciones ni preparado"

"No se sentía el ambiente mundialista"

"No tenía el nivel"

Mucha patria para tan diminutos odiadores de aquí y de afuera.

[RT @RT_com]

Mexican Football fans go NUTS after defeating Ecuador — sea of people surround Angel of Independence