Great work from many of my ex-colleagues at CNIO and H12O. Glad to have contributed with my grain of sand and happy to see this is out in bioRxiv! Stay tuned 👀
If tumour genome evolution is deterministic, can we forecast genomic changes? Yes we can! At least for oncogene amps and tumour suppressor dels. @BHFHeptathlon@Sanroman_Fern present our method for forecasting driver gene copy number change. Preprint: https://t.co/sCasdMrXBp ⬇️1/
Lifestyle is a stronger predictor of aging and mortality than genetics.
A new Nature study of ~500,000 people found:
🎯 17% of mortality variation was linked to lifestyle (exposome).
🧬 <2% of was explained by genetics.
Here’s what you need to know 👇🧵 1/10
🏥 El H12O recibe de la Asociación Española Contra el Cáncer casi 3 millones de € para investigar dos tipos muy agresivos de cáncer de pulmón y de páncreas.
👏 👏 ¡Enhorabuena Luis Paz-Ares, Itziar Otano, José Garrido y Daniela D'Empaire! #somosdel12
➡️https://t.co/SwnPhgm3u6
🎯 Job opportunity! We´re looking for a motivated Bioinformatician interested in clinical-translational oncology to join our team at Dr. Paz-Ares' Lab
Apply now ⬇️
2¹³⁶²⁷⁹⁸⁴¹−1, discovered today, is the largest known prime. It's a Mersenne prime (2ᵖ-1), which are easier to find.
It took nearly 6 years for the GIMPS software to find it after the previous largest known prime. It was also the first Mersenne prime found using GPUs.
This recently published figure by @Sarah_E_Ancheta et al. is very disturbing and should lead to some deep introspection in the single-cell genomics community (I doubt it will).
It demonstrates complete disagreement among 5 widely used "RNA velocity" methods 1/
Understanding complex diseases requires approaches that jointly analyze omic data across multiple biological layers. In our new preprint, we merge data-driven multiomic factor analysis with systematic integration of mechanistic knowledge using COSMOS+ 🧵👇 https://t.co/q5WyTrSn58
📌@ContraCancerEs adjudica la mayor ayuda económica para investigar cánceres de baja supervivencia
2⃣nuevas ayudas:
▶️10 millones-PULMÓN
▶️8 millones-HÍGADO
¡Enhorabuena a nuestros investigadores de ASEICA!
@LuisPaz_Ares,@XRBustelo,@MMalumbres y también a Josep M. Llovet👏
⬇️
Hoy hemos presentados dos grandes proyectos, no solo por el importe (18M€ en total), si no por unir a investigadores y médicos de toda España para investigar cánceres de supervivencia baja: el cáncer de pulmón de células pequeñas y el carcinoma hepatocelular #TodosContraelCáncer