David Machalz ⌬💻

Digital Drug Hunter, Dr. rer. nat., Pharmacist, nature and art enthusiast. No racism, no sexism.

[David Machalz ⌬💻 @damalama01]

After a rather long journey I'm happy to announce that my second key project of my PhD just got published. I used multiscale molecular modeling to discover a novel inhibitor for CYP4Z1. https://t.co/HdvpS4aShs
#compchem

[David Machalz ⌬💻 @damalama01]

Could someone provide me with an invite code for bluesky? #bluesky

[David Machalz ⌬💻 @damalama01]

@JosephYesselman Maybe this is helping?

https://t.co/NhFITIZIOg

[David Machalz ⌬💻 @damalama01]

@jonas_verhellen Berlin University libraries are also really nice for such an endeavour! E.g. Grimm Zentrum. 📚

[David Machalz ⌬💻 @damalama01]

@lizardwithaz Heaven on earth for covalent binders.

[Biomodelling Aarhus Uni @BiomodelAU]

https://t.co/20l0OQ0Fts We have two 2-year Postdoc positions in Computational Chemistry/Computational Biophysics here in Aarhus, Denmark. Deadline Aug. 10th. Please share.

[David Machalz ⌬💻 @damalama01]

Great talks and intriguing discussions continue today at #gcc2022gap
with nice views even firm the buffet.

[David Machalz ⌬💻 @damalama01]

@Blendenfleck Congratulations on the Job! Get to know your environment and colleagues. Chat up your colleagues to get to know them. The first month was very intense with a lot of learning. I went to bed quite early and embraced that I did not have to work on that *one* manuscript. 🙃

[David Machalz ⌬💻 @damalama01]

@jagodamarinic Ja! Ich empfehle die Sendung "mit offenen Karten" mit einer fabelhaften Emile Aubry! Ehrlicherweise sind hier auch einige bedrückende Perspektiven dabei.

https://t.co/N1bRvr4Clf

[David Machalz ⌬💻 @damalama01]

@struc2drug @anunesalves Thanks for the opportunity. I did enjoy it very much as well. 🤗

[BBC Archive @BBCArchive]

Today is Holocaust Memorial Day.

In 1976, Blue Peter’s Lesley Judd met Anne Frank's father Otto, who explained how his daughter's famous diary survived to become a best-seller.

[David Machalz ⌬💻 @damalama01]

@agrossfield @andrewwhite01 @david_koes For the database you could try the human metabolome DB. https://t.co/VcZ8kV3lbO
I tried to identify substrates of a orphaned enzyme this way. Found hits were not of interest for me, but you could give it a look for your case.

[David Machalz ⌬💻 @damalama01]

@DominiqueSydow Very cool @DominiqueSydow. Congratulations!

[David Machalz ⌬💻 @damalama01]

On Wednesday December 1st. I successfully defend my Doctorate in Pharmacy @FU_Berlin on my #compchem research.
Thanks to my PI @gerhardwolber for everything over the last years. #PhDone

[David Machalz ⌬💻 @damalama01]

Hallo. Ich bin David Machalz und ich bin Apotheker und Forscher. Ich bin geimpft. Wissenschaft und Solidarität sind der Weg aus der Pandemie. Deshalb: Lasst Euch impfen! #allesindenArm

[David Machalz ⌬💻 @damalama01]

@anunesalves Sure! Not sure if you are familiar, but there are also these two networking events for molecular modeling in Berlin. https://t.co/36TIONvZHM
https://t.co/QxA41DwdRy

[Simone Fulle @SiFulle]

We still have a Molecular Modelling position open in my team in the lovely Copenhagen area. Focus is on in silico #drugdesign of #biologics, a really exciting research field at the moment given the AlphaFold breakthrough on protein structure prediction. https://t.co/94xkHtdjP8

[David Machalz ⌬💻 @damalama01]

Don't forget that this takes place in the next two days! RDkit is THE toolkit for #cheminformatics and #compchem Also integrated in @knime

[RDKit @RDKit_org]

Registration for the 2021 RDKit virtual UGM is now open:
https://t.co/6jwmHRSUXA

[David Machalz ⌬💻 @damalama01]

PhD position in Computer-aided Drug Design available with the newly formed lab of my former colleague! 10/10 would recommend. #compchem

[Marcel Bermudez @bermudez_lab]

I am thrilled to announce, that I am starting my own lab
@WWU_Muenster
today! We will work on in silico pharmacology and computer-aided drug design with a special focus on GPCRs. I am currently recruiting PhD students so please reach out and retweet. 🥳

[David Machalz ⌬💻 @damalama01]

@bermudez_lab @WWU_Muenster All the best to you,
Really enjoyed working together. I wish you a great start with a lot of interesting science!