Daniel Gedder

PostDoc in Medicinal Chemistry at University College London - UCL

[Daniel Gedder @danielgedder]

The Front Cover shows efforts among Brazilian, American, and European researchers to combat neglected tropical diseases. New heterocyclic compounds originating from Brazil travel to the USA and Europe to be developed as anti‐infective agents against Trypanosomiases. #chemmedchem

[Daniel Gedder @danielgedder]

Mais uma importante publicação de novos agentes anti-infecciosos para o tratamento de Leshimania, trabalho de colaboração com nossos parceiros internacionais e nosso grupo de pesquisa da USP @qhetemlab

[Institut Pasteur Montevideo @IPMontevideo]

🆕💊 Many thanks to all those who made the 'Practical Aspects of Small Molecule Drug Discovery' course at @IPMontevideo possible 🤗!

Here is a video that summarises what happened last week 👇

cc: @eventsWCS @belamalta10 @mbishop_uk @WCAIRDundee @DDU_Dundee

[Daniel Gedder @danielgedder]

O Livro Fundamentos de Química Farmacêutica Medicinal foi publicada pela Editora Manole! Uma contribuição de diversos pesquisadores da área e nosso grupo de pesquisa QHeteM da Faculdade de ciências farmacêuticas de Ribeirão Preto - USP.

https://t.co/SClLSOHtOX

[Edwin Tse @edwintse_]

@OSantibiotics meeting today at 4 pm UK time https://t.co/38UHP8hs5s @MatToddChem @LoriFerrins @danielgedder @macinchem @mfernflower @emeryfs

[drug hunter @drughunter_com]

Molecules of the Month - Feb. 2022 | https://t.co/LlaI7EFJTJ

A glucokinase partial activator, an orexin receptor agonist intended to promote wakefulness rather than sleep, and an orally available diacid, among others this month.

Full review in the slides~

[drug hunter @drughunter_com]

Molecules of the Month – Jan. 2022 | https://t.co/6XYqIXVmJ6

A reversible CoV-2 main protease inhibitor from Shionogi in Ph. II/III which doesn’t require a PK booster like ritonavir is the "Cover Molecule" this month.

Read more about all of them at https://t.co/8dtJi9MSiM~

[drug hunter @drughunter_com]

Molecules of the Month - Dec. 2021 | https://t.co/gJwFeOGSwa

December's cover mol is MRTX1133, a preclinical candidate for KRAS(G12D) mutant cancer. Among others:

-Ph. III candidate from in vivo screening and ML-assisted data processing

-An oral HTT splicing mod for HD

Enjoy!

[drug hunter @drughunter_com]

Molecules of the Month - November | https://t.co/db73sLG7G5

Two oral SARS-CoV-2 antivirals to help tame Covid, a remarkably selective CDK7 kinase inhibitor (>4000x), and a recently approved once-daily MET inhibitor among this month's.

#chemtwitter #biotwitter #medtwitter

[Daniel Gedder @danielgedder]

Estou super contente pois hoje foi a cerimônia de premiação do Small Grant 2021 da RSTMH, uma agência de fomento inglesa que financia projetos de jovens pesquisadores na área de doenças tropicais negligenciadas.
O meu projeto foi contemplado. Grato pelo reconhecimento!

[Daniel Gedder @danielgedder]

O Drug Hunter desse mês apresenta uma série de moléculas e mecanismos fascinantes para o tratamento de diversas doenças. Confira!

[drug hunter @drughunter_com]

Small Molecules of the Month - Sep. 2021 | https://t.co/4A1QrkQdWo

A BLI optimized for single agent antibiotic activity, a biased agonist of S1P1 that minimizes receptor internalization, and an oral AR degrader similar to ARV-110 among the highlights

#chemtwitter #biotwitter

[qhetemlab @qhetemlab]

The new paper from @qhetemlab is online, open and free to read. Follow the link: https://t.co/d5TXTkyuLT

A Collaboration with @UAntwerpen and @WWU_Muenster. A great achievement by @danielgedder

@DNDi_Portugues @DNDi @MrBenGP

[Daniel Gedder @danielgedder]

Development, SAR studies and primary in vivo evaluation of novel isoindolone-based agents against

https://t.co/njHeKaW7zl

[drug hunter @drughunter_com]

Molecules of the Month, Jul 2021 | https://t.co/cgscduflXw

An ER degrader in Ph. III, 4(!) neurology candidates from Takeda, two sulfoximines, and molecule gets ubiquitylated to degrade its target

Follow the team page @drughuntersite for more!

#chemtwitter #biotwitter

[Daniel Gedder @danielgedder]

Agora eu faço parte do time editorial do Drug Hunter. Um excelente site para busca de informações mais atualizadas de Química Medicinal e muitas novidades sobre candidatos a fármacos. Segue o link:

https://t.co/7JBbsWv0nk

@drughuntersite

[Daniel Gedder @danielgedder]

Uma seleção de compostos bioativos de interesse para o tratamento de diversas doenças:
@drughuntersite
https://t.co/YaOqFX5ERy

[Daniel Gedder @danielgedder]

@Anitta Mulher vc hoje está impossível! Continue please. Espero que outros artistas façam o mesmo.

[Daniel Gedder @danielgedder]

Durante meu pós-doutorado na Alemanha na Universidade de Münster, tive eu trabalhei na marcação biológica com flúor 18 de um composto inibidor de CCR2 e CCR5.

https://t.co/mXMsrY9uUD

[Daniel Gedder @danielgedder]

In this study, we modified imidazopyridine/pyrimidine and furopyridine cores at eight different positions to obtain various heterocyclic compounds as anti-infective agents.

[ChemMedChem @ChemMedChem]

.@danielgedder @emeryfs @USPonline @WWU_Muenster @UFSM_oficial @UWdeptMedicine @UAntwerpen report imidazopyridine/pyrimidine- and furopyridine-based compounds as anti-infective agents #antitrypanosomal #drugdiscovery https://t.co/5emXUfP0fE

[Daniel Gedder @danielgedder]

I have designed the Inside front cover - now published in RSC Medicinal Chemistry https://t.co/eAIFXIhJHw