Dan Li

Gastroenterologist. GI cancer prevention.

[CGA-IGC @CGAIGC]

1/Welcome to the #CGAIGCJS Tweetorial on “Long-Term, Prospective Assessment of Cancer Risk in APC c.3920T>A (I1307K) Carriers: Evidence From a Cohort of Over 21,000 Healthy Individuals.” by CGA-IGC communications committee member @DanLiMD
➡️Full article in Gastroenterology @Gastrojournal. 👉🔗https://t.co/yw5DUMrPQk

#HereditaryGICancer
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[CGA-IGC @CGAIGC]

1/Welcome to the #CGAIGCJS Tweetorial on “Raising the Age for Starting Colonoscopy to 35 Years for Individuals With path_MSH6 Carriers May Lead to Missed Opportunities for Detecting Advanced Neoplasia in a Notable Percentage of Carriers.” by CGA-IGC communications committee member @DanLiMD
Full article in @AmJGastro https://t.co/zaV4p1mum0
🧵
#HereditaryGICancer

[CGA-IGC @CGAIGC]

📢Curious about what’s new in the latest @NCCN Guideline updates for Pancreatic Cancer Screening? 🧐📄

➡️Thanks to our Communications Committee member Dylane Wineland, MS, LCGC, who put together an easy, at-a-glance overview highlighting the key changes and some important reminders to keep in mind.

📍Bookmark this resource for quick reference anytime you need it 👇

#PancreaticCancerAwarenessMonth
#HereditaryGICancer

[CGA-IGC @CGAIGC]

In recognition of #PancreaticCancerAwarenessMonth!

1/ Welcome to #CGAIGJS Tweetorial on “Challenges of Early Detection of #PancreaticCancer” by CGA-IGC communications committee member @DanLiMD

Full article in @jclinicalinvest 👉https://t.co/FwrOymp6ao
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#HereditaryGICancer
@Aiims1742 @worldpcc @JulieFleshman

[CGA-IGC @CGAIGC]

1/Welcome to #CGAIGCJS Tweetorial on “Early-Onset Gastrointestinal Cancers: A Review” by CGA-IGC communications committee member @DanLiMD

Full article in @JAMA_current at https://t.co/kjUTiGZNyo

#HereditaryGICancer
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[Gut Journal @Gut_BMJ]

#GUTImages from the paper by Yamada et al entitled

"Precision risk stratification of primary gastric cancer after eradication of H. pylori by a DNA methylation marker: a multicentre prospective study" via

https://t.co/XYIzRt1aLx

#GastricCancer

[CGA-IGC @CGAIGC]

1/ Welcome to the #CGAIGCJS Tweetorial on:
"Germline Genetic Testing in Patients with Advanced Adenomas: A Prospective Study" by CGA-IGC Communications Committee member @annalstrang

📰Full article in @AGA_Gastro 👉https://t.co/0BHTuob42q
🧵

[Ed Esplin, MD, PhD @EdEsplin]

>13% of #patients w/ #GastricCancer had PGVs w/ #germlinetesting

These results support consideration of [#universal] #genetictesting in all #patients w/ #GC

c/w https://t.co/8yRiQfmcvi @SpringerNature @PedroUson et al.
&
https://t.co/wa8YmWUWs3 @VivekSubbiah @Dr_R_Kurzrock @JCO_ASCO
&
https://t.co/tFSemI4b2i @EdEsplin et al. @JCOPO_ASCO

https://t.co/930m1CT8er @JCOPO_ASCO @ASCO @OphirGilad et al.

#access #reducedisparities #precisionmedicine #precisiontherapy #clinicaltrials #precisionprevention

[CGA-IGC @CGAIGC]

1/Welcome to #CGAIGCJS Tweetorial on “Cancer and Overgrowth Manifestations of PTEN Hamartoma Tumor Syndrome: Management Recommendations from the International PHTS Consensus Guidelines Working Group” by #CGAIGC Communications Committee member @MLaszkowskaMD
➡️Full article in @CCR_AARC at 👉 https://t.co/UsPdSSiest

#HereditaryGICancer
@andrewdhawan
@CharisEngMDPhD
@liu_darren9
@CancerMusketeer
🧵

[Ed Esplin, MD, PhD @EdEsplin]

Breaking post-#ASCO25 publication!

>1:8 #patients w/ #gastriccancer/#GC have PGVs on #germlinetesting

35% HRR genes #BRCA1, #BRCA2, etc
17% MMR genes #MLH2, #MSH2, etc

>91% of positive #patients had clinically actionable PGVs based on management guidelines or active #clinicaltrials

"These results support consideration of #genetictesting in all #patients w/ #GC..."

https://t.co/930m1CT8er @OphirGilad et al @UCCancerCenter @JCOPO_ASCO @ASCO @CGAIGC

#access #reducedisparities #universal #germlinetesting #precisionmedicine #precisiontherapy #clinicaltrials #precisionprevention

[CGA-IGC @CGAIGC]

I know these faces look familiar!

Our past president, Bryson Katona, hosted the 2nd annual #CGAIGC "Pints and Polyps" Happy Hour during #DDW2025, providing a👍opportunity for our members to catch up, strengthen connections, & build community outside our annual meeting.

➡️Join us in St. Louis, MO, from October 9–11, 2025, for an unparalleled opportunity to learn, connect, & collaborate! 👉https://t.co/OsbyKS4KYw

📍Become a member & enjoy exclusive benefits—including discounted registration for our annual meeting and much more. Learn more 👉 https://t.co/A9SUvrdke8
#HereditaryGICancer #CGAIGC25

[CGA-IGC @CGAIGC]

1/Welcome to #CGAIGCJS Tweetorial on “Neoplasia Detection Through Colonic Surveillance Among Young Individuals With MSH6/PMS2-Associated #LynchSyndrome” by CGA-IGC communications committee member @DanLiMD
Full article in @AmJGastro at DOI: 10.14309/ajg.0000000000003369 👉https://t.co/e4UT3chtAq
🧵
#HereditaryGICancer #RedJournal

[CGA-IGC @CGAIGC]

1/ Welcome to #CGAIGC Tweetorial on “Diagnostic Utility of FIT in #LynchSyndrome” by CGA-IGC Communications Cttee member @annalstrang

➡️Full article in @AmJGastro at 👉https://t.co/jFfOsEZk5k
🧵
#HereditaryGICancer

[Heather Hampel @HHampel1]

Agreed. In 2025, MSI and MMR IHC should be used to decide who gets immune checkpoint blockade therapy - not to decide who gets germline genetic testing.

[JPGN @JPGNonline]

📈 H. pylori infection significantly elevates fecal calprotectin—often into ranges prompting IBD workup.

HP+ kids had higher FC & were more likely to undergo colonoscopy.

#pediatrics #pedsgi

🔗 https://t.co/w7H6lK62RQ

[Toni Seppälä @Adductor]

🧵1/
🚨 Just out: the PLSD's biggest prospective study yet on Lynch syndrome & colorectal cancer (CRC) surgery.
What’s the real risk of a second CRC—and can surgery prevent it?
Spoiler: Prior CRC = higher risk. Extended surgery = game changer. 👇
🔗 https://t.co/nKmvdFAJrS

[Carl Kay, MD @CarlKayMD]

New ACG Highlights on 🆕 @AmCollegeGastro Guidelines for Diagnosis & Management of Gastric Premalignant Conditions (GPMC)

▪️Endoscopy pearls🔦
▪️Histology pearls 🔬
▪️Recognizing Correa cascade 🦀
▪️Non-dysplastic GPMC Mgmt
▪️Dysplastic GPMC Mgmt

📄 https://t.co/RFdms6knSt

[CGA-IGC @CGAIGC]

1/Welcome to #CGAIGCJS Tweetorial on "@AmerGastroAssn Clinical Practice Update on Screening & Surveillance in Individuals at Increased Risk for #GastricCancer in the United States: Expert Review” by #CGAIGC Comms Cttee member @MLaszkowskaMD

➡️Full article in @AGA_Gastro at 👉https://t.co/tfVKqNZH8D
#HereditaryGICancer
🧵

[CGA-IGC @CGAIGC]

6/
✅ Findings on the index EGD guide subsequent management

@josiebakerGC @pAla2Arg @OphirGilad @KristenCiombor @GillSharlene @KMonkemuller @DrDespina123

[AJG - The American Journal of Gastroenterology @AmJGastro]

📢New ACG Guideline: Gastric Premalignant Conditions

Highlights:
🚨GPMC Dx
🚨endoscopic & nonendoscopic management
🚨histology criteria & reporting
🚨H. pylori eradication
🚨autoimmune gastritis
🚨gastric epithelial polyps

Read: https://t.co/5FRdBCPlbR