πWe've implemented this annotation strategy on a user-hosted web platform, enabling easy data import, query, and export, making it perfect for both internal documentation and large-scale collaborations
π https://t.co/8Xd5muICux
π With controlled vocabularies and required fields, we've enhanced the consistency and ease of annotating sequencing experiments, making data more comparable and accessible. #research#genomics#sequencing
Explore more: π https://t.co/8Xd5muICux
𧬠Our annotation structure covers everything from biological sample prep to library creation, sequencing, and processed files, ensuring data quality, comparability, and ease of use across experiments. #bioinformatics#dataquality
Explore more: π https://t.co/8Xd5muI4EZ
𧬠We explored the regulatory landscape from zygote to organogenesis, revealing the unique topology & chromatin features of active regulatory elements. Fascinating connections for developmental studies! #epigenetics#genomics
Explore more: π https://t.co/bvoSXSDwmX
#devbio
π± With 140,000+ cis-regulatory elements mapped across zebrafish development, weβve identified distinct regulatory classes based on their activity in time and space. Major insights for developmental biology! #zebrafish#genome
Explore more: π https://t.co/bvoSXSDwmX #genomics
π¬ Weβve curated a comprehensive dataset of 1,802 genomic data sets, combining unpublished & re-analyzed data to refine zebrafish annotations, aiding experimental design and advancing developmental genomics. #research#bioinformatics
Explore more: π https://t.co/bvoSXSDwmX
π The international DANIO-CODE consortium has the systematic functional annotation program for #zebrafish, a key model in embryonic development and disease research!
Explore more: π https://t.co/bvoSXSDwmX#genomics #devbio
We at Daub lab are grateful for all the small and big contributions this year and hope that 2025 will be as exciting as this year. Happy New year from us.π₯³
π¨ New Publication Alert! π¨ The DoGA Consortium has unveiled a groundbreaking canine genome annotation in Nature. This atlas of promoter & gene expression across 100+ tissues in dogs, embryos & wolves sets a new standard for genetic research.
https://t.co/FGMCbXGh8n
π§ͺAsthma-linked SNPs such as those near the SBNO2 and SLC19A1 genes coincide with enhancer regions, shedding light on gene regulation mechanisms in childhood asthma.
#SNPs#EnhancerOverlap#AsthmaGenetics
https://t.co/Svr7uJilUa
π§¬A signature of 91 enhancers distinguished between children with severe and mild asthma as well as controls. Discover more here:#duablab#AsthmaResearch#Genetics
https://t.co/mFSEqQqgUG
8,289 identified enhancers linked to mild and severe asthma in children. Read below how this can impact future treatments. #duablab#AsthmaResearch#Genetics
https://t.co/Svr7uJilUa
Publication Alert! WeΒ΄re excited to announce that our research on the gene regulatory enhancers in severe and mild asthma in children in Heliyon. Uncover how these findings could lead to new therapeutic strategies. Read the full article here:
https://t.co/Svr7uJiTJI
Challenging bioinformatics postdoc position @karolinskainst working with gene regulation in the brain: behaviour and psychiatric conditions in dogs, wolves and humans. With collaborator @HannesLohi
https://t.co/l5Tmh1AD4s
#postdocposition#Bioinformatics
The comprehensive atlas of developmental regulatory elements in zebrafish is published today in @NatureGenet https://t.co/CjhNki9yj3. In addition to the BioRxiv submission https://t.co/koMC0IW6fH in this paper we added further resources and results. (1/n)
Your #postdoc mission with @DogGenome, should you accept it, is to find how regulatory elements determine behavioural differences between different dog breads and wolfs, and how these are related to human psychiatric conditions.
https://t.co/s4LppsbUwB
Help us as #postdoc at @karolinskainst and @DogGenome to find out how brain region-specific gene regulatory elements determine behavioural differences between dog breads and wolfs, and how they might be related to human psychiatric conditions. #Jobs#postdocjobs#Bioinformatics