Follicular lymphoma, duodenal type➡️Follicular dendritic cell meshworks (CD21/CD23/CD35+) are pushed to the periphery of the neoplastic follicles (“HOLLOW” meshworks), in contrast to preserved meshworks usually seen in nodal/systemic FL #hemepath#pathtwitter#lymsm#MedTwitter
A FREE, OPEN ACCESS online textbook of thoracic pathology!
The thoracic mega index now has nearly 300 posts, including tips for practice, detailed videos with WSI and discussions between expert pulmonary pathologists, sample pathology reports, and LOTS of high quality images, organized by topic.
https://t.co/Ny4tWhJy6P
Mediastinal grey zone lymphoma, classic Hodgkin lymphoma-like:
🩸Confluent pleomorphic cells admixed with eosinophils & dense fibrotic stroma
🩸Uniform strong expression of CD20, PAX5 & at least one additional B marker (CD19, CD79a, BOB1, OCT2)
🩸CD30+
#hemepath#lymsm
CC12. 2nd Gloomy sunday, ideal to review errors (promised @Venkateshgilly2 ). 75 y/o woman with a skull lesion. A carcinoma is obvious. Reasoning: first consider lung and breast. TTF1 (shown), GATA3 was -. My diagnosis was met adeno, most probably pulmonary #cytology#CytoPath
A 68-year old male presented with arthralgias and skin rashes. A complete blood count performed shows MCV of 80 fl and low platelet count. Peripheral smear and bone marrow images are shown. Which mutation is likely to be identified in this condition? #pathoboards#pathtweetorial
Burkitt lymphoma, EBV+, HIV setting
Per 5th edition of the WHO, a three-part nomenclature is now recommended:
1) Name of lesion
2) virus status
3) Type of immunodeficiency
Navigate the slides: https://t.co/hKLI92Q3YR | Case 3
#hemepath#lymsm#pathtwitter
(1/2) Please join us in an educational event to mark the retirement of Dr. Steve Swerdlow
===> Monday 11/14, 11am-5:15pm EST <===
*Link to join on Microsoft Teams:
https://t.co/0MIPBRddle
Can you make the diagnosis from this pic? Only one tumor looks like this (ok, maybe 2).
WSI digital slide 🔬 https://t.co/WBuuWU9cA9.
Answer & DDX ✅ https://t.co/ZGPtZVODD4.
Video ⏯️ https://t.co/io7WsRFKdA
#BSTpath#pathologists#pathology#pathTwitter
Circulating neuroblastoma in peripheral blood, flagged as "blasts" by Sysmex. Concurrent bone marrow exam showed extensive involvement by disease. #PathTwitter#hemepath
#WHOHEME 🧵#3 is dedicated to the ever-elusive IgG4-related disease
IgG4-RD is an immune-mediated disease w/mass-forming lesions w/a lymphoplasmacytic infiltrate⬆️IgG4+ #PlasmaCells &“storiform fibrosis” typically w/ ⬆️serum IgG4 titer. Image source https://t.co/wFm0CmUX5p