Systematic review 14 studies assessed Lung ultrasound (LUS) (vs HRCT) to detect RA-ILD (using threshold of ≥ 5 B-lines) found sensitivity was 86.8% (95% CI 80.1–91.4), specificity 75.4% (95% CI 62.3–85.1), and AUC 0.890 https://t.co/GlNpsPBwtS
Life Essential 8 (LE8) score studied in RA & SLE was neg. corrlated w/ DAS28 (r −0.96) & SLEDAI (r − 0.81) & assoc w/ 10 yr survival. LE8 score: smoking, sleep, physical activity, diet, BMI, non-HDL, BP, fasting glucose, & HgbA1c. https://t.co/DCpWKzmt80
Lung is involved in pre-clinical ACPA+ RA! Lung-resident B cells from BAL of 12 untreated at-risk or Dx early RA pts found T cell–driven B cell differentiation resulting in local class switching and somatic hypermutation B cells, esp w/ ACPA+ https://t.co/ZPwRf3ZWAl
✅ Check the latest findings about the pathogenesis of #Rheumatoid#vasculitis ⬇️ our recent paper with @MertzP@drALINAdima@FChasset & ClaraW. Just as for #Lupus, the deleterious role of tobacco #smoking is immense 😭
📥 DOWNLOAD LINK: https://t.co/mHFMlLhVDy
Our paper about lung ultrasound in SSc-ILD is finally online! 3 years work: glad of what we have created, proud of what @davidemrb has honed!
#systemicsclerosis#SSc-ILD #lungultrasound
https://t.co/UKX4LSSn5r
2023 SLE Recommendations
🔹Lower GC dose (5 mg instead of 7.5)
🔹 Early use of biologics for corticosparing
🔹 Cyclophosphamide if life-threatening
🔹 MMF: new in hemato manif
🔹Lupus nephritis: VCL vs BEL???
🔹Maintain trt for 3 years then taper, except HCQ
#EULAR2023
NZ
#Behcets Disease by the lovely Gulen Hatemi #EULAR2023
1/2
🍃Sensitivity of the pathergy test has ⬇️! PCV23 vax to ⬆️⁉️
🍃AZA works for most manifestations, as do TNFi, ⬆️ing use of TNFi as 1️⃣st line
🍃Anticoagulation is controversial, use in special situations, ❌ if aneurysms
2023 update @EULAR recommendations imaging in GCA
What's new:
1. US = first line imaging test
2. Axillary arteries should be included in standard examination
3. Alternative imaging FDG-PET or MRI
4. Takayasu: MRI preferred CT or FDG-PET alternatives
@Rheumnow#EULAR23 LB0008
⏰ Welcome to the 4th day of #EULAR2023#congress!
Do not miss the last session on #scleroderma this year “New and latest Targets in Systemic Sclerosis and Localised Scleroderma”, from 12:45 - 13:30 CEST (Gold Room)
@Worldsclerofnd
👉https://t.co/Wp7geUn78x
⏰ #EULAR2023#congress 2nd day is starting!
📌Do not miss the session dedicated to new insight on the pathogenesis of #scleroderma and # myositis
that is scheduled 1st June 10:30-12:00 CET (Space 2)
@Worldsclerofnd
👉https://t.co/wDSu1YesfV
⏰ #EULAR2023#congress#Milan is starting today!
Do not miss the first lecture on #scleroderma in the session “Everything is difficult to treat?”, which is scheduled for 31st May from 15:00-15:15 CET (South Hall, Session room 1)
@Worldsclerofnd
👉https://t.co/Wp7geUn78x