Please have a read of our newest paper "Increased Replication Stress Determines ATR Inhibitor Sensitivity in Neuroblastoma Cells": https://t.co/pj7myCBj9e. Thread explaining it below 1/n
@kls_kat@DennisRenMD@DFTBubbles@Damian_Roland And as an anecdote saw a neonate once crying/unsettled. Admitted for obs. Did bloods - all normal but sent a blood culture. Didn't start abx. Seen on morning w/r, had been well and was going to be d/c'd until lab phoned through blood culture ? Strep (was GBS bacteraemia).
@kls_kat@DennisRenMD@DFTBubbles@Damian_Roland I've seen a lot of people 'hold' them until starting abx. Depends on whether you think BC stand alone as a useful investigation without necessarily treating. I think they do.
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@mstotty88@ldwijesinghe@NHSE_WTE Totally. But if one SHO is on a NWD and one is post nights who else is there to do the routine stuff. It's an imperfect system. I've been through it.
@mstotty88@ldwijesinghe@NHSE_WTE Yes, it's consultant led and delivered. But it's probably not the role of the consultant to be doing ward admin, routine procedure lists, clerking chemo admissions etc. Generally consultant expansion would be justified by increased activity not covering other roles.
@mstotty88@ldwijesinghe@NHSE_WTE Do you think that sort of consultant expansion is required in your specialty? Eg. radiology might accommodate but my own probably doesn't. But we need more people to staff the rotas.
@mstotty88@ldwijesinghe@NHSE_WTE I suppose it's 20% people who are post CCT. The concern would be ending up like neurosurgery with lots of people unable to get consultant jobs and having to do lots of fellowships etc.
@DrDonSharkey @RCPCHtweets Problem is trainees always provided vast majority of service esp. at middle grade level. LTFT breaks this link. But we don't necessarily need more CCT holders. So who covers the service? Fellows, SAS doctors etc are hard to find.
@jonathan_davis3@drbretty So in certain units in the UK, CRP>40 = LP. NICE say > 10 or used to, which I followed for a while. It's a low yield investigation for sure.
Our newly funded project looking at the role of copy number alterations in embryonic development/paediatric tumour initiation (a collaboration with @bryantlab1) has just kicked off-we are grateful to @CCLG_UK/@LPTrustUK for their continuous support: https://t.co/hRsEt5zMny
@jakepmann This is all very true. The only other thing I'd add, is that it needs to be fundable, however that is defined. You can't do research without money.