DD

Early to #crypto, late to Twitter. Red Sox + Pats Nation lifer. #fintech #blockchain. CSO / CoS / COO

[Barry @BarryOnHere]

The last time the Knicks had a lead in the NBA Finals was June 17th, 1994.

Yes, the same day as this:

[Jessica S. Tisch @NYPDPC]

Beautiful day marching up Fifth Avenue with @MikeBloomberg for the annual Israel Day Parade.

The NYPD was not messing around with security: this was the most extensive security plan that the NYPD has ever put together for this event so that everyone could celebrate safely.

Thank you to every member of the NYPD who was out today protecting our city.

[Rapid Response 47 @RapidResponse47]

.@SecScottBessent: "A nation that cannot manufacture, mine, ship, or refine its needs gradually cedes its strength and sovereignty to others. That is a dangerous dependency for any country; it is an unacceptable one for the United States of America."

[The White House @WhiteHouse]

Weekly reminder: Decline is a choice.

[Juan Benet @juanbenet]

Episode 3 of my new podcast features Dr. Jacques Carolan (@JacquesCarolan), a founding Program Director at ARIA (@ARIA_research), the UK’s Advanced Research and Invention Agency. He directs two neurotech programs aimed at one of the most important opportunity spaces: developing tools and systems to interface, at scale, with the human brain.

One program is built on the idea that brain disorders are circuit problems, and funds tools to target those circuits with molecular precision across the whole brain. The other aims to deliver high-performance neurotech to the brain non-invasively or at most in a 30-minute outpatient procedure.

We dig into the engineering and biology behind both programs, potential scaling unlocks for the field, how ARIA programs drive breakthroughs, Jacques background, the role of media in shaping the future, and much more. I hope you enjoy the conversation!

Other links to this episode and references below.

Chapters
00:00:00 Introduction
00:01:22 Why 20 years of neurotech breakthroughs haven't reached patients
00:04:08 The two variables that determine whether any medical technology gets adopted
00:09:17 Brain disorders cost the UK £100B/year and we're barely treating them
00:16:15 Using stem cells and gene therapy to build better brain interfaces
00:21:40 Self-regulating gene therapy that helps the brain quiet its own seizures
00:24:03 The non-technical reasons transformative neurotech fail to reach patients
00:31:34 Watching a 30-second brain ablation stop severe tremors
00:38:11 The case for delivering brain implants and therapies without opening the skull
00:50:56 Why high technical uncertainty makes distributed teams better than vertical integration
01:02:55 Why the UK keeps producing world-class neuroscience but not world-class neurotech companies
01:11:04 What AI-driven hypothesis generation means for breakthroughs per pound
01:20:40 From quantum computing to improv comedy to running £119M government brain programs

[Kevin O'Leary aka Mr. Wonderful @kevinolearytv]

We uncovered something far bigger than I ever expected. After seeing coordinated false attacks against the Utah data center project, we brought in an advanced data science team to trace where the content was coming from and the results were shocking. What we found led back to organized networks, political activist groups, and funding trails tied to massive international entities. We dug through IRS 990 filings, tracked IP data from around the world, and uncovered what appears to be a coordinated campaign targeting energy and data center projects across multiple regions.

I shared 90 pages of evidence with federal law enforcement and raised concerns directly with contacts at the White House. This isn’t speculation. The filings, funding records, dates, and connections are documented. There’s a coordinated PR war happening around energy infrastructure and data centers, and we’re not going to ignore it.

[Lacey @lacey_wisdom]

Congrats to our portfolio company @zama on their acquisition of @TokenOps_xyz 🥳

[DD @ddedde10]

@lacey_wisdom @plcapital fascinating as always!

[Lacey @lacey_wisdom]

At @plcapital we believe the GPT moment for robotics is closer than many believe, with innovation in the sector rapidly advancing and we see cryptographic and decentralized primitives as central to this narrative 🧵 1/5

[Crewkerne Man @CrewkerneMan]

Kemi Badenoch just ripped into Keir Starmer at PMQs, exposing how he is prioritising Russian oil over the North Sea, she went on to accuse him of getting ‘further into the bunker’ before rightly declaring the Labour Party as Britain’s number one problem.

Fantastic!

[James Maslow @jamesmaslow]

I’m Jewish. I have family history that makes what’s happening in NYC right now impossible to ignore. This past week, mobs targeted synagogues in Brooklyn. A child was attacked. This is not politics, this is hatred, in plain sight, and too many people are scrolling past it. I made this video because silence has a cost. History has proven that. “Never Again” is not a slogan. It’s a responsibility. And that responsibility is yours too, whether you’re Jewish or not. Watch this. Share it. Say something. #neveragain

[DD @ddedde10]

@MrMikeBlake @RashidaTlaib @RepRashida you should read some history.

[Josh Wolfe @wolfejosh]

20. All excerpted from the BRILLIANT must-read article by @RoyKAltman
https://t.co/GFGgGZABN7

[Josh Wolfe @wolfejosh]

20. All excerpted from the BRILLIANT must-read article by @RoyKAltman
https://t.co/GFGgGZABN7

[GRANDPA’s FREE ADVICE @GOP_is_Gutless]

It took less than 24 hours for brokers to tighten the belt after the Supreme Court ruled that brokers could be held liable for carrier accidents WOW!

#Truckers #trucking #truckinglife @topfans

[Bianna Golodryga @biannagolodryga]

“‘In my 18 years in government, I have not seen a threat environment quite like this one,’ Ms. Tisch said…In 2025, 330 of the 576 recorded hate crimes in New York City targeted Jewish people, according to Police Department data.”
https://t.co/7LbZrEL2Wo

[Kevin O'Leary aka Mr. Wonderful @kevinolearytv]

Why is there suddenly such an aggressive push against American data centers and AI infrastructure? After seeing a major spike in coordinated opposition campaigns around our Utah projects, we conducted a digital audit and traced a large amount of the activity back to an organization called Alliance for a Better Utah, which has been pushing misinformation throughout Box Elder County about our data center developments. What’s even more concerning is where the funding appears to originate. After reviewing IRS Form 990 filings and tracing the network behind it, the money appears tied to Chinese linked funding channels connected through an organization called Arabella. Think about the incentive, if China is racing to dominate AI and compute capacity, why wouldn’t they want to slow American infrastructure down?

[Gad Saad @GadSaad]

💯

[DD @ddedde10]

@CptAllenHistory this fact stuff sure is becoming an inconvenient trend …. cc: @NYCMayor

[John Kennedy @SenJohnKennedy]

You don't have to be a senior at Cal Tech to figure out why inflation rose to 9% under President Biden.

He spent billions of dollars and threw money around like it was confetti.

This gutted the middle class like a fish.

[DD @ddedde10]

@MOSSADil more history for you @NYCMayor