Dad | Physiologist | Postdoc @KatsuFunai studying Alport Syndrome (XLAS) | PhD @UMassO2MLab | Mitochondria are my first love | Views are my own, no endorsements
So proud of these two! It's been an exhausting road to get this clinical trial off the ground, but it was great to finally showcase off our pilot work on weight loss/GLP-1 agonists on mitochondrial efficiency! @ACSMNews
I'm grateful to have been awarded the "Outstanding Postdoctoral Scholar" award for @uofunuip! More great things to come in the world of mitochondria, GLP-1 (esp with Elizabeth on my team, who won Outstanding MS Student), and Alport Syndrome!
New preprint! This was the first project I took on when I started my postdoc. It took some twists and turns, but it turned out to be great!
https://t.co/rGn8bUu5N0
My life as a bald person and a dad to a 4-year-old girl in one post: I nicked myself shaving my head this morning and was bleeding. My daughter used up all of the normal Band-Aids, so I had to use one of her mermaid Band-Aids.
@Chrest_brett I have the same qualms with "aging"
I've yet to be convinced that aging, per se, is a problem. Age-related disease is a problem, but healthy aging? Yet to be convinced. Why the fixation to avoid death?
@MitoPsychoBio I'm not convinced that we need to. Why is living an optimal life a necessity?
I think it's great for the people that are able to figure it out, and perhaps it's necessary for people who are athletes/performers/etc. but I don't know why it's so emphasized for the average Joe?
@CAS_ReproLab@MitoPsychoBio Living systems spend their entire existence trying to reverse change, and biological turnover (DNA repair, protein turnover, etc) is likely an attempt to maintain a single entropic state. Homeostasis, by definition, opposes thermodynamic increases in entropy.
@CAS_ReproLab@MitoPsychoBio Sure, it's a tricky (arguably impossible) set of observations to quantify. There are far too many variables to account for.
But I think when it boils down to some philosophical concepts, what truly separates biological life from other universal objects is entropic maintenance
@CAS_ReproLab@MitoPsychoBio This also means that death is the inability to maintain the thermodynamic state required for life, and the energy contained within living systems then must dissipate throughout the universe, in accordance with thermodynamic law
@CAS_ReproLab@MitoPsychoBio The way we measure energy expenditure actually reflects the release of energy from our intact thermodynamic system. Thus, the observation that increased EE negatively correlates with lifespan is actually due to LOSS of entropy within the body
@CAS_ReproLab@MitoPsychoBio In that perspective, what separates life from other objects in the universe is the unique ability to capture and stabilize energy within a contained system.
Or, in other words, life depends on the ability to store energy and resist the distribution of energy
"Your claim is denied because congenital disorders aren't covered after age 26"
Oh, because my cleft lip and palate magically took care of themselves once I turned 26. How stupid of me.
Heading out to #KidneyWeek with my faithful travel companion!
I'm so honored to have been awarded a People's Choice Award for the @ASNKidney Basic Science Forum! This will be such an exciting trip!