Deepak Shilkar

Editor at @Editage Generalised specialist. @UCL alumnus. Hakuna Matata!

[Deepak Shilkar @deepakshilkar]

निस्त्रैगुण्ये पथिविचरतः कोविधिः कोनिषेधः

The one who wanders in the path devoid of all the three qualities, for him there is no law and no prohibition.

#शुकाष्टकम्

[Deepak Shilkar @deepakshilkar]

@LocasaleLab All the best! Wishing you success.

[Deepak Shilkar @deepakshilkar]

@mbeisen Stoned?

[Deepak Shilkar @deepakshilkar]

@DuttShekhar

[Jim Haseloff @jimhaseloff]

Instructions for building EZ-Gels - cheap agarose mini-gels for DNA separation with 3D printed vessel, dams and comb, glass microscope slide base, conductive plastic electrodes and low ionic strength buffer. https://t.co/1CuqyaC55o

[Prof. Dr. Sezgin Bakırdere @SezginBakirdere]

İyi bir insan olmadan iyi bir akademisyen olunmaz, o-lu-na-maz!!!

Kural Net: Akademisyenlerin “H-indeks” (Hirsch indeksi) değerinden ziyade “i-indeks” (İnsani İndeksi) değeri yüksek olmalıdır!

Çünkü;
-Bir öğrencinin hayatına dokunabilmek çok sayıda makale yayımlamaktan daha önemlidir.

-Bir öğrencinin saygısını kazanmak binlerce atıf almaktan daha makbuldür.

-Yetiştirdiğiniz öğrenciler tarafından unutulmamak aldığınız patent sayısından çok daha kıymetlidir.

-Bir öğrencinin derdi ile dertlenmek alınan akademik ödüllerden daha değerlidir.

[Rikiya Takehi @rikiyatakehi]

We asked GPT-6 Astra to edit Qwen3.5-0.8B weights to improve math.
It directly changed only 0.016% of weights, fixing 0.8B's reasoning loops & improving math up to 6x and even instruction following 3x, without gradients or training.

We call this Weight-Space Programming: frontier LLMs can now natively read/write neural network weights! 🧵
Blog: https://t.co/bOWCcFhCVq

[Wojtek Stawski @StawskiWojtek]

Just got 3 peer review reports and they are NOT generated by AI! If the referees are reading my tweet - thanks for your unpaid work and all the comments, really appreciated! 🥰

[mar! @fwtospatho]

a good professor will change your life

[Hannes Believer @BiotechHannes]

@mbeisen Same conclusion after two decades in and around labs: culture beats format every time. And culture is usually set by how genuinely the PI engages with each project. (The pastries point stands too.)

[Deepak Shilkar @deepakshilkar]

@dinomanu @india_plus_ I also think businessess should nore frequently incubate ideas from within their institution if they cannot flourish and grown in the existing structure as spin offs. Then it is upto them to absorb or let them fly.

[Dinesh Modi @dinomanu]

Valid point!

[Deepak Shilkar @deepakshilkar]

@manojpandey66 When I was a JRF, I did not receive stipend for almost 1 year. I finally received it 2 years after quitting the position.

[Nassim Nicholas Taleb's Wisdom @TalebWisdom]

"How much you truly believe in something can be manifested only through what you are willing to risk for it." - Nassim Nicholas Taleb in Skin in the Game

[Deepak Shilkar @deepakshilkar]

@LocasaleLab This answers most of my questions.

[Deepak Shilkar @deepakshilkar]

@PrinceArihan @DrPramodPSawant This is near Osia? Have come across them a couple times I think

[Deepak Shilkar @deepakshilkar]

small caveat though. endogenous translation of the mitochondrial ORF is not firmly proven

[rico meinl @ricomnl]

mfw
>biology is just a data problem
>collect enough omics, simulate the whole cell
>read about humanin
>peptide encoded inside the mitochondrial 16S rRNA gene
>the same sequence is also a structural part of the ribosome
>24 aa if the cytosol translates it, 21 aa if the mitochondria do
>because mitochondria run a different genetic code
>and start translation with N-formylmethionine instead of plain methionine
>nobody's fully sure which one actually makes it
>also 13 nuclear copies that might make their own versions
>gets secreted into the blood
>hits cell-surface receptors
>one of them is literally a mitochondria detector
>also gets taken back up
>binds Bax inside the cell to block apoptosis
>discovered by screening surviving brain tissue from an alzheimer's patient
>open my cell model schema
>compartment: yes
>molecule_type: rRNA, peptide, hormone
>length: depends who's asking

[Nathan @nathan_liow]

Physics is hard to visualize through static images alone, so I turned my 174 pages of high school physics notes into an interactive website.

It covers mechanics, electricity, and magnetism, breaking down complex concepts into intuitive visualizations, real-world scenarios, and interactive problems.

Check it out here: https://t.co/8wUqbiwA1k

[Tobias Wenzel 👨🏼‍💻👨🏼‍🔬🧫🔬⚙️ @MakerTobey]

🎉 New preprint! We built a fully open-source, 3D-printable droplet microfluidics platform with strobe-enhanced microscopy — sharp images of fast-moving droplets without a high-speed camera. All files on GitHub. #OpenScience #Microfluidics #OpenHardware
https://t.co/22G3wEsJEF

[Parmita Mishra 🔬 @parmita]

i made an atlas of all diseases in the world and what's left to solve

and it is a LOT. a LOT is left to solve.