Deep Genomics

Transforming #genomics with #deeplearning

[Deep Genomics @deepgenomics]

4/4: P104:  DeepMirBind: A Deep Learning Approach for MicroRNA Target Site Prediction and Design of Upregulation Oligonucleotides

[Deep Genomics @deepgenomics]

We're at the #OTS23 Meeting this week -- excited to share updates on our application of #AI to the discovery and development of #oligonucleotide and #RNA therapeutics.

Stop by to learn more at the following 4 posters.

https://t.co/mCM9aAxpS6

[Deep Genomics @deepgenomics]

3/4: P041:  BigRNA: A Large Neural Network Enabling Accurate Oligonucleotide Design and Variant Effect Predictions

[Institut Vecteur @InstitutVecteur]

Découvrez ce nouveau travail étonnant du sponsor bronze de Vecteur @deepgenomics et du cofondateur de Vecteur, Brendan Frey. Comme indiqué ci-dessous, l'équipe a développé le premier modèle de base pour les thérapies ARN 👇

[Vector Institute @VectorInst]

Check out this amazing new work from Vector Bronze Sponsor @deepgenomics & Vector co-founder Brendan Frey. As outlined below the team developed the first foundation model for RNA therapeutics 👇

[Eric Topol @EricTopol]

The first foundation #AI model for RNA
https://t.co/aNsRMbEuAu
Predicting protein and microRNA binding sites, tissue-specific expression, variants -> gene expression and splicing ++
@deepgenomics @frey_brendan and colleagues

[Deep Genomics @deepgenomics]

16/16 We hope that our model BigRNA, and more RNA foundation models like it, will continue to transform the fields of disease variant interpretation and personalized therapeutics

[Deep Genomics @deepgenomics]

We are thrilled to share our manuscript ‘An RNA foundation model enables discovery of disease mechanisms and candidate therapeutics’ as a preprint! 🧵

https://t.co/izQ0eV9bzc

[Deep Genomics @deepgenomics]

15/16 Here it’s important to have accurate predictions to lower the number of drugs screened. We analyzed variants in ClinVar that are amenable to this approach.