We have an opportunity for someone to join our fabulous bioinformatics team - https://t.co/2R4zxqUsjz - you will get to work with @nanopore@illumina @bionanogenomics @10xGenomics and more! Please retweet and dm for info!
Rapid #genome-wide copy number profiling using adaptive sampling on @nanopore by @mattloose and the amazing team @DeepSeqNotts
Real potential for clinical application.
This gif is from one sample of three run on a single @nanopore promethION flow cell. Frankly I'm super impressed at the performance though there is headroom for more improvements. We ran the same libraries as on gridION and have updated our preprint here. https://t.co/oZwRN8vji0
We've put out a short preprint today showing some updates in Readfish for @nanopore adaptive sampling. https://t.co/GQJJkIql33 @alexomics is giving a talk shortly at the #nanoporeconf about this - but a short thread here.
Earlier this week we put out a couple of preprints (https://t.co/tDtMuyAOLF https://t.co/RF3f3Tr5KE) describing minoTour https://t.co/veMHrXt2J2, an @nanopore tool we have been developing for several years. A bit of a 🧵
I still remember the first time I saw data from @scalene showing ultra long reads (N50>=100kb) were possible. Since then we and others (especially @DrT1973) have worked to get longer reads. This weekend we tested the @circulomics@nanopore ultra long kits. Wow! 19.49 Gb N50 143kb
So - our ReadFish paper came out on Monday https://t.co/LWx6m1HHXZ using GPU - but what if you only have a laptop? Here's an update from @alexomics to our tools that enable ReadFish on Mac, Linux or Windows with no additional GPU or compute. https://t.co/CgicPm4nUH for details.
So - our ReadFish paper came out on Monday https://t.co/LWx6m1HHXZ using GPU - but what if you only have a laptop? Here's an update from @alexomics to our tools that enable ReadFish on Mac, Linux or Windows with no additional GPU or compute. https://t.co/CgicPm4nUH for details.
Many application spin out of this on the fly selective sequencing. Tunable custom target panels to genome gap filling..... things get very interesting from here.
Great to see this paper out - loads of hard work from @alexomics and many others to get this completed - adaptive sampling on @nanopore sequencers targeting hundreds of genes to depths in excess of 40x on a single flowcell. https://t.co/LWx6m1HHXZ
Announcing the Visium Spatial Gene Expression for FFPE Scientific Challenge! Share how you’d use Visium Spatial to unlock the full story of your FFPE tissue samples to win an experiment performed by us. Enter by 12/23. Learn more: https://t.co/wvDmoiSCJd #spatial
About to start out 100th @nanopore run for covid samples with the team from @DeepSeqNotts . A sad milestone but amazing work by our local team including many from @TeamNUH and @PostdocPat all in support of the work of @CovidGenomicsUK .
@kirk3gaard@nanopore We recommend this for samples of “unknown origin”. Let’s say someone wants to run a large batch of samples that they’ve extracted. A check on a Flongle (or minion flowcell with a flush) can quickly reveal sample problems. Good sample in - great data out.
Massive achievement for @TeamNUH Microbiology lab, one of the first labs in the UK to obtain UKAS accreditation for SARS-CoV-2 PCR. A true testament to the hard work & dedication of the micro team, maintaining <24-hr TAT & high quality, end to end service for our patients.