DEEPTHI RAMESH

Postdoc Scholar @UCSF
Medicinal chemistry, Oncology, Virology, Infectious diseases, NTDs, Biopolymers, Small molecule drug discovery, Organic synthesis

[Guillaume Laconde @Glaconde34]

Workflow for E3 Ligase Ligand Validation for PROTAC Development | ACS Chemical Biology https://t.co/KyJEOxQvpJ

[Darryl B McConnell @D_B_McConnell]

Here are the ten approved HIV protease medicines. The first nine all used the same design strategy to address the flap water. The last took the alternate approach and replaced it. https://t.co/r5hpB7GbpK

[DEEPTHI RAMESH @deepthiramesh92]

Celebrating new publication.
We demonstrate novel #imidamide based linkage for attaching #smallmolecules based on #drugdesign principles to #chitosan.

https://t.co/nGk0oqkLWg

#polymer #biomaterial #Researchpaper #postdoc #Chemistry #biopolymer

[JCIM & JCTC Journals @JCIM_JCTC]

DEL-Dock: Molecular Docking-Enabled Modeling of DNA-Encoded Libraries #MolecularDynamics
https://t.co/B0McyTMMTR
@KShmilovich @Tkaraletsos
Vol63 Issue9 #JCIM #compchem

[DEEPTHI RAMESH @deepthiramesh92]

Seeking postdoc position #polymer #medicinal #biomaterial #postdoc
Please feel free to reach out if you have any inquiries or potential opportunities to discuss.
https://t.co/rvqYSnv88i
https://t.co/0qgSIpBNwU
https://t.co/H6KgrbGLTo
https://t.co/gCRxw29eZs

[Aedin Culhane (@[email protected]) @AedinCulhane]

Incredibly useful "cheatsheet" on cancer chemotherapy classes.

From Cell Press
https://t.co/A19G0Weag5

[Pengyu Yang @Pengyu19]

Discovery of an Oral, Beyond-Rule-of-Five #Mcl-1 Protein–Protein Interaction Modulator with the Potential of Treating Hematological Malignancies https://t.co/sM9HteJMk6

[Cell Press @CellPressNews]

First woman possibly cured of HIV by transplanting HIV-resistant stem cells from umbilical cord blood.
@persaud_deborah @UCLA

Read more in @CellCellPress

[Science Magazine @ScienceMagazine]

Over the last 10 years, the #CRISPR toolbox and its applications have profoundly changed biological research, enabling advances through applications in plants, animals, and humans.

A recent #ScienceReview highlights a decade of the technology: https://t.co/AptQ1SwlXW

[Marwin Segler @marwinsegler]

Lipinski’s Rule of 5 has been highly influential in guiding Med Chem in the past 25 years. What does it offer for the next 25 years of drug discovery? @HartungIngo and colleagues provide answers here: https://t.co/T86SMVlEg4

[Corey S. Powell @coreyspowell]

Researchers have discovered the first known "virovore," an organism that feeds on viruses. Probably there are many others like it -- an entire, previously unknown food chain.
One day into 2023, and already things are going topsy turvy.
https://t.co/OvYfKM45Fm #ecology #life

[Darryl B McConnell @D_B_McConnell]

Here's the slide that took me 6 months to make. The six classes of molecular interactions for drug design. Clearly H-bonds are the first thing to master as a drug designer followed by pi-pi and sigma-sigma interactions.

[Ingo Hartung @HartungIngo]

This is in my eyes the most important annual paper for students preparing for a job interview in medicinal chemistry (or process chemistry): provides a great overview about representative drug structures, their targets & synthetic routes used. @ACSBioMed https://t.co/DtjIBLEPXZ

[T Govindaraju @govindaraju_tgr]

PERSPECTIVE in Journal of Medicinal Chemistry-
Mechanistic Insights for Drug Repurposing and the Design of Hybrid Drugs for Alzheimer’s Disease https://t.co/jYiK9eGYeJ
@Drug Repurposing @Repurposing @drug development @Alzheimer's disease @demnetia @ACSPublications

[RSC Chemical Biology @rsc_chembio]

🔥 New advance article for RSC Chemical Biology! 🔥 Nathan W. Luedtke et al @mcgillu exploring [4 + 2] and [2 + 4] #cycloaddition reactions on single- and double-stranded DNA! #chembio #bioorthogonal

🧐Read the #OpenAccess article 👉https://t.co/iz7YXHXvjy

[V. G. Balaji (Ph.D.) @VGBalaji2]

Latest article: Chitosan with pendant (E)-5-((4-acetylphenyl) diazenyl)-6-aminouracil groups as synergetic antimicrobial agents
https://t.co/DVIv7hNHGd
@JMaterChem @RoySocChem @deepthiramesh92

[Matthew Clark @Matthew_BaTiSiO]

The Stimulator of interferon genes (STING) is key to the innate immune system's response to pathogenic DNA. STING dimers in the ER change shape upon binding the secondary messanger cGAMP (green), and this allows them to oligomerize and move to the Golgi. #blender #b3d #sciart

[V. G. Balaji (Ph.D.) @VGBalaji2]

@Arch_Pharm

[DEEPTHI RAMESH @deepthiramesh92]

Glad to have latest publication @Wiley @Arch_Pharm.
https://t.co/suYTd3XVP3