Denic Lab

The Denic lab studies selective autophagy, proteostasis, tail-anchored proteins, and more! It is what it is @MCB_Harvard
Account run by Vlad and students

[Denic Lab @denic_lab]

Check out Vlad's ASCB Award Essay: "Advice to a young scientist (by someone who doesn’t know how to give it)"
https://t.co/LAvh2MZeEF

[Denic Lab @denic_lab]

The 26S Proteasome Utilizes a Kinetic Gateway to Prioritize Substrate Degradation
https://t.co/kCinZt9yHy

[Denic Lab @denic_lab]

Ubiquitination of ABCE1 by NOT4 in Response to Mitochondrial Damage Links Co-translational Quality Control to PINK1-Directed Mitophagy
https://t.co/v0nbyyyto2

[Molecular Cell @MolecularCell]

Probing the Global Cellular Responses to Lipotoxicity Caused by Saturated Fatty Acids https://t.co/qVWJrmsuWw

[Denic Lab @denic_lab]

"Yeast waits for no man"
-Vlad Denic

[Shoemaker Lab @shoemaker_lab]

Our CRISPR/autophagy/TMEM41B manuscript is finally out at PLOS Biology. https://t.co/6VQHM41Jxw

[Denic Lab @denic_lab]

Visualization of Compartmentalized Kinase Activity Dynamics Using Adaptable BimKARs https://t.co/hmDrZkokrG

[Denic Lab @denic_lab]

Systematic analysis of ribophagy in human cells reveals bystander flux during selective autophagy
https://t.co/KBnpLTcNtg

[ShorterLab @ShorterLab]

The AAA+ ATPase TorsinA polymerizes into hollow tubes with a helical periodicity of 8.5 subunits per turn: https://t.co/3M2YuTAZt7

[Rachel Lily Terry @rlilyterry]

Very excited to share that this work with @GabrielNeurohr & @AngelikaAmon is now online in @CellCellPress!
What happens if cell size increases but DNA content stays constant?

"Excessive Cell Growth Causes Cytoplasm Dilution And Contributes to Senescence"
https://t.co/oHHnfIk1QZ

[Denic Lab @denic_lab]

Disruption of the beclin 1–BCL2 autophagy regulatory complex promotes longevity in mice https://t.co/2YacyuJhTj

[Denic Lab @denic_lab]

Genome-wide CRISPR Analysis Identifies Substrate-Specific Conjugation ... https://t.co/FJ4HuCPqfY

[Denic Lab @denic_lab]

Great initiative @CdeCBo @MCB_Harvard

[Oscar Hernandez Murillo @Oahm95]

CdeBo19 has been an amazing experience! Club 8 students have learned so much; now they know more about biochemistry and protein engineering. I think their favorite protein might be Hsp104. Thanks, Amber, Jim and Shorter lab for the help! @ShorterLab @DaTDP43aboutFus @CdeCBo

[Denic Lab @denic_lab]

Vlad Denic aka Mission Hipster!

[Dyche Mullins et al. @MullinsLab]

Scientist photo challenge. #7scientistchallenge 7 portraits of 7 scientists posted over 7 days. Photos must be your own. Nominated by MYSELF and nominating @ryochem.

Day #7 (I fell behind): Vlad Denic, 2007
(Canon PowerShot G7)

[Denic Lab @denic_lab]

Distinct proteostasis circuits cooperate in nuclear and cytoplasmic protein quality control https://t.co/OvUhWkoWPs

[Denic Lab @denic_lab]

A Membraneless Organelle Associated with the Endoplasmic Reticulum Enables 3′UTR-Mediated Protein-Protein Interactions https://t.co/XFgILtcNQb

[Denic Lab @denic_lab]

Congrats to grad student Andrew on earning a fellowship from the American Federation for Aging Research!

[MCB_Harvard @MCB_Harvard]

MCO Student Wins Fellowship https://t.co/G021zM8OGz

[Denic Lab @denic_lab]

CAN1 Arginine Permease Deficiency Extends Yeast Replicative Lifespan via Translational Activation of Stress Response Genes https://t.co/4nYZgrPwqO

[Denic Lab @denic_lab]

A Novel Class of ER Membrane Proteins Regulates ER-Associated Endosome Fission https://t.co/85nu2JPvKg

[Denic Lab @denic_lab]

MARCH6 and TRC8 facilitate the quality control of cytosolic and tail‐anchored proteins https://t.co/6tRHhMDkrg

[Denic Lab @denic_lab]

NUFIP1 is a ribosome receptor for starvation-induced ribophagy https://t.co/yyWaeHvCck