Denuja Karunakaran, PhD 👩🏽‍🔬🔬🧬🫀

🇦🇺🇨🇦Lab Head @MonashBDI @VicHeartInst|Director @atheroaussie| Atherosclerosis,Obesity,macrophage inflammation| #macrophage_yogi|#positive_mentor| my opinion

[Denuja Karunakaran, PhD 👩🏽‍🔬🔬🧬🫀 @denujak]

👇🏽Research @NatMetabolism https://t.co/lputXT3FIs

An inflammatory gene, RIPK1, increases obesity risk.

Our follow-up intervention study @IMBatUQ also shows promise...watch this space for more updates! 👍🏽

#obesity #genetics #RIPK1 #inflammation

@UQ_News @HeartInstitute

[7NEWS Queensland @7NewsBrisbane]

A Queensland scientist is leading a world study that uncovered an inflammatory gene responsible for obesity. Blocking the gene could stop weight loss in its tracks, helping millions of Australians. https://t.co/VZ3A1cpmr5 @BrittanyCLane #7NEWS

[Waggoner Lab @LabWaggoner]

Macrophages can engulf targets whole (phagocytosis) or nibble them in small fragments (trogocytosis), a decision controlled by cortical tension in the targets (high tension favors former, low latter)
https://t.co/bWqUvSxpRs
https://t.co/eBZHkmmHb6
@NatureCellBio @UCBerkeley

[Monash Victorian Heart Institute @MonashVHI]

What if the future of treating heart disease could be a 'one-and-done' therapy?

A first in human gene-editing study, led by @ProfSNicholls, showed a reduction in LDL by up to 50% and triglycerides by 55% - with a single infusion.

🎥 Watch @AHAScience tv: https://t.co/eHViuoxfJc

[Hanrui Zhang @hanrui_zhang]

🚨 Our new publication in Nature Communications!
 Macrophage WDFY3 protects against autoimmunity by boosting efferocytosis and dampening T cell activation.

🛡️ A safeguard for immune homeostasis.
https://t.co/Uk6mxPny5I

[Denuja Karunakaran, PhD 👩🏽‍🔬🔬🧬🫀 @denujak]

@hanrui_zhang Whoah!!! Congratulations @hanrui_zhang 👏🏽👏🏽👏🏽🎉🎉🎉🎉 Great work! 👍🏼

[Denuja Karunakaran, PhD 👩🏽‍🔬🔬🧬🫀 @denujak]

@AWeinstock So well deserved!!! Congrats @AWeinstock 🎉🎉🎉🥳🥳🥳🥳🥳

[AAS @atheroaussie]

Abstract submission is open for our annual scientific meeting!
Submit via: https://t.co/sTWiLKzT5Z

[Denuja Karunakaran, PhD 👩🏽‍🔬🔬🧬🫀 @denujak]

Great writing tips for students #positive_mentor

[David Sinclair @davidasinclair]

12 lessons students learn in the Sinclair Lab:

Lesson 1. Write the way you speak

[Leslie Vosshall PhD @leslievosshall]

Reminder that our obsession with journal names as a lazy proxy for "impact" is new.

Here are the key papers that led to the GLP-1 Lasker Award for Svetlana Mojsov:
Mojsov et al JBC 261:11880 1986
Mojsov et al JCI 79:616 1987
Mojsov et al JBC 265:8001 1990

Journal of Biological Chemistry
Journal of Clinical Investigation

[PHD Comics @PHDcomics]

How long it takes...

[The Nobel Prize @NobelPrize]

In 1928, Alexander Fleming discovered the mould he was working with produced a substance that could kill many common bacteria. He called this new, exciting substance "mould juice". Only after a couple of months did he name it penicillin.

#WorldAntibioticAwarenessWeek

[Monash Victorian Heart Institute @MonashVHI]

Victorian Heart Institute and Hospital Director @ProfSNicholls is leading world-first trials for genetic high cholesterol, expanding potentially life-saving treatments for those at risk of heart attack and stroke, presented at @American_Heart.

Read: https://t.co/OW8GpHS5Ha

[Dr Michael J Houghton @mjhoughton89]

Day 2 at @BDI_MDOP #MDO2024 and we have @denujak from @MonashVHI presenting her work on the therapeutic knockdown of the RIPK1 pathway to reduce diet-induced obesity and improve insulin sensitivity 🤩👏🏼

[Denuja Karunakaran, PhD 👩🏽‍🔬🔬🧬🫀 @denujak]

True purpose - ‘what’s next? What can I do?”

[The Nobel Prize @NobelPrize]

Demoted four times and threatened with deportation, 2023 medicine laureate Katalin Karikó's journey in science was difficult but she persevered: "You have to channel all your energy into seeking out 'What's next? What can I do?'"

Listen to her interview: https://t.co/0m7AY99uLz

[Denuja Karunakaran, PhD 👩🏽‍🔬🔬🧬🫀 @denujak]

Well done @emma_solly!! Very well deserved! An excellent talk! 👏🏽👏🏽👏🏽Must be a proud supervisor @jotan80 ❤️

[AAS @atheroaussie]

The ECR Rising Star Award Winner at the #AASASM24 was Dr Emma Solly. Congratulations on a fantastic contribution and exciting data. Thanks to CSL for sponsoring our Rising Stars.🌟

[Hudson Institute of Medical Research @Hudson_Research]

Our Director & CEO, Prof Elizabeth Hartland AM is among an impressive group of health & medical leaders named Fellows of the Australian Academy of Health & Medical Sciences. Congratulations @ProfHartland! 🥳

#AAHMSFellow @AAHMS_health

Read more here: https://t.co/ArCchd31mv

[EMBL Australia @EMBLAustralia]

Huge congratulations to our Scientific Head, Prof James Whisstock, on his election as an #AAHMS Fellow for his contributions to the field of #immunology & beyond!

[Denuja Karunakaran, PhD 👩🏽‍🔬🔬🧬🫀 @denujak]

#proudPI. My Postdoc presented some exciting work within 3 mths of starting! Very exciting times. Congrats Narmadaa at being an AAS ECR Finalist @MonashVHI @MonashBDI

[AAS @atheroaussie]

One of the highlights of the meeting is always seeing our Rising Stars shine and this morning it was the ECRs who did the shining! Dr Dragana Dragoljevic, Dr Emma Solly, Dr Jordyn Thomas & Dr Narmadaa Thyagarajan.

[AAS @atheroaussie]

Fantastic talk on TRAIL by Dr Sian Cartland from ⁦@KavurmaMary’s group⁩! There’s still so much we don’t know. Also, congratulations to Dr Cartland who’s a new Group Leader ⁦@HRIAust⁩ 👏🏽👏🏽👏🏽

[Denuja Karunakaran, PhD 👩🏽‍🔬🔬🧬🫀 @denujak]

#proudPI @atheroaussie

[AAS @atheroaussie]

PhD student Han Xu delivered a great flask talk on RIPK1 in macrophages and regulation of inflammation. @denujak

[Denuja Karunakaran, PhD 👩🏽‍🔬🔬🧬🫀 @denujak]

Very exciting and interesting talk @KerryRye @atheroaussie! #T1D #atherosclerosis

[AAS @atheroaussie]

Our first national plenary was delivered by long time AAS member and lipoprotein expert, Prof Kerry-Anne Rye who talks us through their recent data in therapeutic options to reduce cardiometabolic disease.