Cancer Dependency Map Sanger

[Cancer Dependency Map Sanger @DepMapSanger]

The data is now available.

[Cellosaurus @Cellosaurus]

@rebecca_poulos @biorxivpreprint @CMRI_AUS @Garnettlab @sangerinstitute @DepMapSanger @emanuelvgo When is the data going to be in PRIDE?

[Cancer Dependency Map Sanger @DepMapSanger]

The latest contribution to #depmap from the team. Enjoy.

[Garnett Lab @Garnettlab]

Congratulations to the team. We hope the community find these data useful @DepMapSanger. I'd like to make special mention of the skilled & dedicated scientific technical staff @sangerinstitute and #Procan that make possible generation of these large datasets. @TechsCommit.

[Garnett Lab @Garnettlab]

We're recruiting a Senior Staff Scientist to map genetic interactions to understand epistasis in health and disease. Come help lead a multidisciplinary team to tackle this fundamental challenge in our understanding of genes and genomes. https://t.co/bzN64j3MNS #sangerinstitute

[Garnett Lab @Garnettlab]

Grateful to have contributed to this study mapping dependencies in OSCS from Asian patients as part of @DepMapSanger. Phenomenal work from Annie Wei & Sok Cheong @reversecancer and @sangerinstitute team @fiona_fb3 @emanuelvgo stacey price @ultanmcd @jgrgilbert #depmap

[Garnett Lab @Garnettlab]

(1/5) We are delighted to share the updated Project Score database (https://t.co/PU6EPimYrE) and accompanying paper @NAR_Open (https://t.co/heUl4g2uyE). The Project Score database uses CRISPR screens to investigate cancer dependencies and prioritise candidate targets.

[Garnett Lab @Garnettlab]

Elegant analysis of the mechanism underpinning WRN dependency in MSI tumours and great to see the field moving forward so rapidly. congratulations to the team involved.

[Cancer Dependency Map Sanger @DepMapSanger]

If you like DepMap this opportunity could be for you!

[Garnett Lab @Garnettlab]

Don't miss this opportunity! Opening for Head of Data Science at Mosaic Therapeutics. Mosaic is a new spin-out from the Sanger using advanced computational methods and next-generation cancer models to find new synthetic-lethal cancer targets. Please RT
https://t.co/gy66BOV2U2

[Garnett Lab @Garnettlab]

Good protocols are critical for advancing science. Thanks to the work of the technical team @sangerinstitute to produce these beautiful SOP for deriving and culturing tumour organoids. Includes tips, images and videos, all freely available. @TechsCommit #depmap @CancerDepMap

[Garnett Lab @Garnettlab]

Nice to see this summary on using @DepMapSanger to study drug MoA from @boehmjesse and @DrFranVazquez. #depmap.

[Garnett Lab @Garnettlab]

The GDSC website (https://t.co/IBaBFz6NN7) has been upgraded with two new features to enhance your analysis. GDSC hosts differential drug sensitivity data across 1,000 human cancer cell lines for hundreds of anti-cancer drugs, together with genomic biomarkers of drug sensitivity.

[Garnett Lab @Garnettlab]

This is great work by @DepMapSanger @CancerDepMap working collaboratively to bring together an integrated dataset for 800 cell lines. Have fun everyone who, like us, enjoys working with these rich datasets! #depmap #CRISPR

[Garnett Lab @Garnettlab]

Our review on "Genomics-guided pre-clinical development of cancer therapies", published with @SpringerNature in @NatureCancer is now out! SharedIt link: https://t.co/BJ45tVeNkb [https://t.co/7A7hMECNM3]. Many thanks to coauthors @HayleyFrancies @ultanmcd. #CancerResearch

[Garnett Lab @Garnettlab]

CELLector is useful new tool that mines clinical data to define molecular sub-types and then maps these onto in vitro cancer models. This can help you find the right cell model for your work. Congratulation to @HannaNajgebauer @Francesco_i0ri0 and team. Part of @DepMapSanger

[Garnett Lab @Garnettlab]

My webinar on using functional genomics for cancer drug discovery is now available to view here: https://t.co/y3iPNbDZOq. Join me for a live Q&A at 1pm today. @DepMapSanger #depmap

[WesselsLab_NKI @wesselslab_nki]

Open position for a Junior Group Leader in AI for Oncology at the Netherlands Cancer Institute. Feel free to get in touch ! @hetAVL @NKI_nl
More info here: https://t.co/xFa1QGvyT9

[Cancer Dependency Map Sanger @DepMapSanger]

We'll be showcasing some of the different ways we're using #depmap data for drug discovery. @Garnettlab

[Garnett Lab @Garnettlab]

Please come along if you're interested to learn how we're using functional genomics data - including CRISPR screens - to inform multiple aspects of drug discovery including target discovery and drug mechanism of action.

[Cancer Dependency Map Sanger @DepMapSanger]

This is important work to track and prevent further transmission of #COVID19. It leverages world-class capabilities for DNA sequencing and analysis built up over decades. Thanks to the dedicated team @sangerinstitute and across the UK making this possible.

[Wellcome Sanger Institute @sangerinstitute]

In response to the ongoing #COVID19 pandemic, we will deploy our large-scale genome sequencing platform, alongside regional sequencing centres, to better understand the coronavirus outbreak in the UK
https://t.co/AEOSdhR75r

[Garnett Lab @Garnettlab]

Great career opportunity as a Senior Staff Scientist in our lab (https://t.co/3dh2hOkeSV). Help lead our efforts using functional genomics to study genetic epistasis in cancer. A diverse and challenging role with opportunity for development. Closing date March 26th. Please RT.

[Cancer Dependency Map Sanger @DepMapSanger]

New data release from GDSC project includes 60,434 new IC50 values from 70 additional compounds. The total dataset now includes 446,000 dose response curves for 565 drugs. All available through the GDSC data portal: @https://www.cancerrxgene.org/ #Depmap

[Gosia Trynka @GosiaTrynka]

I'm delighted to share that I have joined @targetvalidate team as Experimental Science Director and I look forward to working more closely with the fantastic Open Targets community.
https://t.co/OwhGcWGC2c