Devis Benfaremo

MD, PhD | Internal medicine and clinical immunology | Marche Polytechnic University

[RMD Open @bmj_rmdopen]

🧵 Is #Tocilizumab a disease-modifying treatment for #SystemicSclerosis?

In a real-world French-Italian cohort of 197 patients:
✅ ILD stabilised and progression fell from 43% to 24%
✅ Skin fibrosis improved in dcSSc
✅ Digital ulcers, arthritis and cardiac biomarkers improved
✅ Acceptable safety profile

Raised CRP predicted better treatment persistence, supporting a more personalised approach to therapy.

🔗 https://t.co/hGSkUTWbnO

#SSc #ILD #Rheumatology

[ACR_Journals @ACR_Journals]

Progressive pulmonary fibrosis is increasingly recognized as a key determinant of outcomes in SSc-associated ILD.
New Expert Perspective in Arthritis & Rheumatology discusses current definitions, risk factors, screening strategies, and evolving therapeutic approaches, with a focus on practical management challenges and treatment escalation in progressive disease.

https://t.co/bwLCJxNcUS

[Devis Benfaremo @devismd]

@jan_novantuno Concordo…già divorata la quarta. Per quanto ci siano delle inverosimiglianze a livello di trama, ha ritmo e ci sono dei personaggi indimenticabili…tipo ted lasso e shrinking

[Eric Topol @EricTopol]

Our ability to achieve immune tolerance to prevent autoimmune diseases keeps expanding, now with 2 new reports on use of T reg cells (last week's @NobelPrize) @ScienceTM @ScienceMagazine
https://t.co/6x2hidX6f0

[World Scleroderma Foundation @Worldsclerofnd]

📊 Today at #EULAR2025 | 10:30–12:00 CEST
📍 Room 6.4
🗂️ Oral Abstracts: Insights from Registries in SSc
💡 Early indicators, antibody phenotypes, calcinosis, cancer risk, & AI-driven screening
Speakers: Di Donato | Colic | Moschetti | Guler | Tonutti
#Scleroderma #EUSTAR #WSF

[EULAR @eular_org]

🎉 Celebrating Research Excellence at #EULAR2025!

EULAR proudly recognises the exceptional contributions of researchers, medical students, health professionals, and patient advocates.

Congratulations!

#Rheumatology #ScientificExcellence #Innovation

[Devis Benfaremo @devismd]

@AndreaMinuz https://t.co/hLpCbeaKwY

[Devis Benfaremo @devismd]

@emmevilla Come votano quelli nati dopo il 1989?

[Devis Benfaremo @devismd]

@em1lystone It’s crazy…every 2024 movie deserved an Oscar more than this year’s ones

[Guido Vitiello @guidotweet]

Parti a razzo su una cosa di cui si sa poco; ma parti così a razzo che, se la realtà ti smentisse, non potresti tornare indietro se non al prezzo di una figuraccia. E così ogni discussione razionale è compromessa.

N.B. Vale per tutti i casi, e per tutte le fazioni impegnate

[Devis Benfaremo @devismd]

@TheCinesthetic True detective season 1

[Alfonso Lanzieri @alfo_lanzieri]

Ciò che dice Walter Siti sulla letteratura (invero anche su altro) andrebbe fatto leggere come introduzione allo studio della stessa a tutti gli studenti; soprattutto oggi, tempo in cui perfino le teorie scientifiche devono essere moralmente buone, educate, democratiche.

[Tânia Santiago @TaniaLSantiago]

👉Algorithm for the management of Raynaud’s phenomenon and digital ulcers in SSc, in https://t.co/EyOihnpS6W
#esclerosesistemica#raynaud#digitalulcers#ulcerasdigitais#systemicsclerosis

[ERN ReCONNET 🇪🇺 @ern_reconnet]

🧡@ern_reconnet joins t #WorldSclerodermaday 🌻
⚕️SSc is an orphan systemic #ConnectiveTissueDisease characterized by #autoimmunity, fibrosis of t skin n internal organs n vasculopathy
📰 Read t news for our ALL resources, links n info (freely available) https://t.co/wiRg8ImYDp

[Annals of the Rheumatic Diseases @eular_ARD]

Exciting results by Greg Deener showing complete immune reset after CD19/BCMA compound CarT cell treatment, leading to long term remission in lupus nephritis. After 6 month no patient received IVIG supplementation. #SLE #EULAR2024

MS

[Marta Mosca @MartaMartamosca]

Laurent Arnaud at EULAR2024
HOT: lupus what’s on the horizon?
@Lupureference @ern_reconnet @eular_org

[Annals of the Rheumatic Diseases @eular_ARD]

Insightful review on the use of CarT cells in autoimmune diseases from Prof Schett at #EULAR2024.
MS

[Annals of the Rheumatic Diseases @eular_ARD]

Car T cell to treat autoimmune diseases : a presentation from Pr Schett. #EULAR24 come join us Hall D

[Eric Topol @EricTopol]

"A radically new approach to replacing the haematopoietic [blood cell] system.....the potential to be used for other diseases that benefit from depleting lymphocytes and replacing a diseased immune system, such as severe autoimmune diseases, and maybe even HIV infection. @Nature
https://t.co/6ypRWqQLMO
@SGaraude @UniBasel

[World Scleroderma Foundation @Worldsclerofnd]

📣 Big Changes, Same Mission!

🌐 After months of dedication and hard work, we are proud to launch our redesigned website, a vital step in our journey of innovation and engagement with the scleroderma Community.

https://t.co/IiaqEmNjnc