🧵 Is #Tocilizumab a disease-modifying treatment for #SystemicSclerosis?
In a real-world French-Italian cohort of 197 patients:
✅ ILD stabilised and progression fell from 43% to 24%
✅ Skin fibrosis improved in dcSSc
✅ Digital ulcers, arthritis and cardiac biomarkers improved
✅ Acceptable safety profile
Raised CRP predicted better treatment persistence, supporting a more personalised approach to therapy.
🔗 https://t.co/hGSkUTWbnO
#SSc #ILD #Rheumatology
Progressive pulmonary fibrosis is increasingly recognized as a key determinant of outcomes in SSc-associated ILD.
New Expert Perspective in Arthritis & Rheumatology discusses current definitions, risk factors, screening strategies, and evolving therapeutic approaches, with a focus on practical management challenges and treatment escalation in progressive disease.
https://t.co/bwLCJxNcUS
@jan_novantuno Concordo…già divorata la quarta. Per quanto ci siano delle inverosimiglianze a livello di trama, ha ritmo e ci sono dei personaggi indimenticabili…tipo ted lasso e shrinking
Our ability to achieve immune tolerance to prevent autoimmune diseases keeps expanding, now with 2 new reports on use of T reg cells (last week's @NobelPrize) @ScienceTM@ScienceMagazine
https://t.co/6x2hidX6f0
🎉 Celebrating Research Excellence at #EULAR2025!
EULAR proudly recognises the exceptional contributions of researchers, medical students, health professionals, and patient advocates.
Congratulations!
#Rheumatology#ScientificExcellence#Innovation
Parti a razzo su una cosa di cui si sa poco; ma parti così a razzo che, se la realtà ti smentisse, non potresti tornare indietro se non al prezzo di una figuraccia. E così ogni discussione razionale è compromessa.
N.B. Vale per tutti i casi, e per tutte le fazioni impegnate
Ciò che dice Walter Siti sulla letteratura (invero anche su altro) andrebbe fatto leggere come introduzione allo studio della stessa a tutti gli studenti; soprattutto oggi, tempo in cui perfino le teorie scientifiche devono essere moralmente buone, educate, democratiche.
👉Algorithm for the management of Raynaud’s phenomenon and digital ulcers in SSc, in https://t.co/EyOihnpS6W
#esclerosesistemica#raynaud#digitalulcers#ulcerasdigitais#systemicsclerosis
Exciting results by Greg Deener showing complete immune reset after CD19/BCMA compound CarT cell treatment, leading to long term remission in lupus nephritis. After 6 month no patient received IVIG supplementation. #SLE#EULAR2024
MS
"A radically new approach to replacing the haematopoietic [blood cell] system.....the potential to be used for other diseases that benefit from depleting lymphocytes and replacing a diseased immune system, such as severe autoimmune diseases, and maybe even HIV infection. @Nature
https://t.co/6ypRWqQLMO
@SGaraude@UniBasel
📣 Big Changes, Same Mission!
🌐 After months of dedication and hard work, we are proud to launch our redesigned website, a vital step in our journey of innovation and engagement with the scleroderma Community.
https://t.co/IiaqEmNjnc