Shrestha, Bag, Xing, @ychengsy & co analyze polymorphic mobile element insertions in human populations, chromatin marks, and HiC data to identify safe harbor regions to insert transgenes. They find 19 candidate loci in blood and 5 in brain https://t.co/mSfMnTmAVu
Our study on identifying tissue-specific Genomic Safe Harbors (GSHs) for gene therapy is out!
https://t.co/fbIqplpFWD
For gene therapy, the integrated transgene cassette needs to: 1. not affect endogenous gene function (safety), 2. have stable expression (efficiency).
1/4
A peculiar loss of a sense of smell or taste appears to be a common #COVID19#coronavirus symptom in reports from multiple countries, and is increasingly used to guide recommendations to self-quarantine. https://t.co/E87N9Dih8R
Everyone working remotely:
ZOOM monitors the activity on your computer and collects data on the programs running and captures which window you have focus on.
If you manage the calls, you can monitor what programs users on the call are running as well. It's fucked up.
It feels like even more of a special privilege these days to be a physician-scientist working with incredible lab members & colleagues like Jing Zeng, Yuxuan Wu, Chunyan Ren @JKeithJoung@lucapinello John Manis @scotwolfe1 & more who enabled this study
NEW in @genomeresearch: "Researchers from @HarvardChanSPH identified ribosomal DNA epigenetic features that may serve as clocks for estimating biological age in humans and other mammals." Full article --> https://t.co/OwLfyox0lc featured in @GenomeWeb --> https://t.co/CsO4AgRURj
@mattswain123 I’m extracting my own custom property, and it does extract the property that I am looking but the name of the compound that it is extracting is from some other paragraph