Tbh, if you get something like Lembo and you mitigate the insomnia, you most likely won't experience any side effects. You can just take one pill and sleep 12 hours without problems. I think right now we have a lot of opportunities to run tren with very little to no side effects, which doesn't mean to run mega dosages because it's still a lot of damage, but looking into the perspective of 50-100 mg, it's pretty high ROI on that.
The funniest part about Tren discourse is everyone knows the horror stories but almost nobody knows the actual pharmacology.
There is basically ONE old human clinical study of injectable Trenbolone acetate.
Krüskemper, Morgner & Noell Arzneimittelforschung, 1967.
PMID: 5632439
Humans received 5–10mg Tren A IM every other day for ~14 days.
At 5mg EOD, Tren produced measurable nitrogen retention, exactly what an anabolic steroid is supposed to do.
A reconstruction of the individual nitrogen-balance data gives the 2 responders roughly ~41–44% retention ratios.
For context, several older anabolic drugs measured using similar nitrogen-balance methodology clustered around ~22–25%.
That does NOT prove Tren is “2x as anabolic.”
n=3.
Only 2 responded.
Different studies/diets cannot be perfectly compared.
But the signal is still insane considering the dose.
And the rest of the pharmacology points in the same direction:
• extremely strong AR agonism
• very high anabolic potency per mg
• increased nitrogen/protein retention
• strong skeletal-muscle anabolic signalling
• anti-catabolic potential
• increased bone/anabolic signalling
• reduced adiposity in animal models
• does not aromatize into estradiol
A later preclinical paper found Tren increased androgen-sensitive muscle mass ~35–40% while partially preventing bone loss and visceral-fat accumulation.
Tren has serious cardiovascular, endocrine and neuropsychiatric liabilities. None of this makes it safe.
But “Tren is cattle poison with no positive pharmacology” is equally stupid.
The interesting scientific position is that Tren appears to be an extraordinarily potent anabolic molecule with an extraordinarily bad risk profile.
Both can be true.
@roidsand2dfoids You are Black, and you have no right to speak. Little boy can't handle some weights at the gym. I can smell the Indian shit through my monitor
Modafinil and bromantane are the golden duo; they should work, the half-life is shorter, there are fewer sleep issues, and so on. I don't think it's too much dopamine; it just depends on what your dose is, and maybe it's just too much stimulation for you, which L-theanine could help with to get away with the jitteriness and so on, or alpha GPC. plenty more things out there
TAK-653 is something you’d usually take daily. It’s mainly interesting for mood and synaptic plasticity, and there’s research around depression and other cognitive/psychiatric effects. I think it’s currently in clinical trials.
You could run it alongside modafinil. Adding something more dopaminergic like 9-Me-BC or bromantane would make it a pretty interesting combination
As for memantine, it has some interesting mechanisms too, but it’s a very different drug and I wouldn’t treat it as a direct modafinil replacement.
Not medical advice, obviously.
I'm literally taking less than a g of gear lol.
And that's not for even a long time. I think you know that you just don't explode and become a 300 lb dude after injecting gear.
Whatsoever, I don't want to be obese, even if it's muscle.
My goal is to stay 200 lbs and that lean. But whatever you think, idc. I am healthier, younger, and better looking than you all day long.
You are literally obese, lmao. Where is your fucking waist? You are build is the same as from an obese guy. won't even knew if you did go to the gym