Diego Pesce

Synthetic biologist, evolutionary biochemist, overall a natural philosopher. Sometimes musician, dancer, and teacher. Tweet also for @RNAMaker.

[David Bikard @dbikard]

If like me you've run hundreds of minipreps but never bothered to read up on why they extract plasmid but not chromosomal DNA, a recent tweet by @joel_rosenbaum finally motivated me to look it up. From Biennium and Doly 1979:

[Haelixa @haelixa]

Facing New Heights!: Last week we took a team trip to neighboring canton Schwyz.
We were able to take a step back from the usual day-to-day business, reset, and nourish our team relationship. Now we are back and as fresh as a daisy! 🌼

#teambuilding #transparencyisinourdna

[Diego Pesce @diepesce]

Race to survival during antibiotic breakdown determines the minimal surviving population size https://t.co/WGoOHaQb3f

[bioRxiv Evobio @biorxiv_evobio]

The fitness landscape of TEM-1 β-lactamase is stratified and inverted by sublethal concentrations of cefotaxime https://t.co/V1Rm14P0ey #biorxiv_evobio

[Diego Pesce @diepesce]

Machine learning-aided engineering of hydrolases for PET depolymerization | Nature https://t.co/5sc70MfVCF

[Diego Pesce @diepesce]

https://t.co/zli1enBmz9

[Diego Pesce @diepesce]

Co-evolution of interacting proteins through non-contacting and non-specific mutations https://t.co/Y1OCYlpZWm

[Diego Pesce @diepesce]

https://t.co/rk3Zi6H1Pq

[iDEC @iDEC2026]

The registration is now open for iDEC2022! https://t.co/nnDzUrQoN9
We invite all students from high-school to PhD to compete in the 3 directed evolution areas:
-Molecular⚛️
-Pathway🔁
-Genome🧬
Teams will present their solution at the iDEC2022 festival with great talks and prices

[iDEC @iDEC2026]

The 1st iDEC Festival opens! @ProfTomEllis @nadanai263 @zakir_tnimov @FrostJiangShan @Corbicula1 Thanks to all the teams, judges, volunteers! @imperialiDEC @DrLeoRios @meeeeechigan @diepesce @SvenjaVinke @FankangMeng @StefanBassler @HuandiXu @MingzheChen3 @alexis_zeng

[bioRxiv @biorxivpreprint]

Evolutionary transition from a single RNA replicator to a multiple replicator network https://t.co/vs3NhAtWQq #bioRxiv

[Joshua L. Payne @joshualevipayne]

Open postdoc position in our group @ETH_en. Please RT.

https://t.co/ILjkMjTBI3

[bioRxiv @biorxivpreprint]

Evolution of a minimal cell https://t.co/q256woLBnI #bioRxiv

[Diego Pesce @diepesce]

Towards an engineering theory of evolution | Nature Communications https://t.co/k8KgIc3MHB

[JoeThornton @JoeThorntonLab]

Our new paper on experimental evolution of reconstructed ancestral proteins: Historical contingency is the dominant factor in evolution of protein sequence variation, even under strong selection. Out today in @eLife. 1/
https://t.co/AiPd4Jga9s

[Chris Knight @knightjjar]

Our complete landscape of antimicrobial peptides: https://t.co/uK1NY8h4AF work of @PsamClark with @curtisbdobson @Lynda_K_Harris plus Tom Jowitt and me in @CommsBio Thanks to @uom_bbsrc_dtp
not to mention @dbkell for setting up the collaboration!

[Diego Pesce @diepesce]

https://t.co/EmnI0rnnrt

[Stefan O. Bassler @StefanBassler]

I would like to invite all students to apply for the first International Directed Evolution Competition 2021! @iDEC2021 @EdinburghUni
Teams will compete in the tracks of molecular, pathway or genome directed evolution with a focus on methods or output.
https://t.co/tYgORvSLjY

[Life Science Alliance @LiSciAlliance]

Interested in directed evolution? Check out the @iDEC2021 comp for students (undergrad, masters, high school) to compete in teams on projects in 1/3 tracks: enhancing molecules, optimizing pathways or designing new strains.

PhD students & postdocs can sign on as advisors too!

[Diego Pesce @diepesce]

Metabolic fitness landscapes predict the evolution of antibiotic resistance | Nature Ecology & Evolution https://t.co/cacexxnoXC