Wubin Ding

Postdoc at Salk Institute for Biological Studies, working in computational epigenetics, machine learning, deep learning, software, and algorithm development.

[Wubin Ding @DingWubin]

Excited to share our new bioRxiv preprint. We profiled DNA methylation + 3D chromatin interaction in 197k+ nuclei from 8 human basal ganglia subregions using snm3C-seq, integrated to a 261k-cell atlas revealing cell-type & region-specific epigenomes.
Link: https://t.co/fHmJb50BnH

[Wubin Ding @DingWubin]

· We identified specific non-MSN neuronal cells that differ in distribution and in transcriptional and epigenetic identity across the matrix-striosome boundary

[Wubin Ding @DingWubin]

Excited to share our new bioRxiv preprint. We profiled DNA methylation + 3D chromatin interaction in 197k+ nuclei from 8 human basal ganglia subregions using snm3C-seq, integrated to a 261k-cell atlas revealing cell-type & region-specific epigenomes.
Link: https://t.co/fHmJb50BnH

[Wubin Ding @DingWubin]

· Medium spiny neuron subtypes show regionally organized epigenomic and 3D genome signatures aligned with dorsal–ventral identities
· Integrated regulatory maps link cell-type–specific enhancers to disease-associated genetic risk in the human basal ganglia

[Wubin Ding @DingWubin]

Key highlights:
· A multimodal single-cell atlas maps DNA methylation and 3D genome architecture across human basal ganglia cell types and subregions
· Neuronal and non-neuronal cells exhibit distinct chromatin compartmentalization, looping, and methylation landscapes

[Qiurui Rachel Zeng @zengqiurui]

Why are older individuals more prone to neurodegenerative diseases?

Very excited to share our new #bioRxiv from @JoeEcker. We study age-related epigenetic changes in the brain, highlighting on cell-type-specific transposon demethylation and TAD remodeling. We also present a deep learning framework that predicts and interprets age-related transcriptional changes using multi-modal epigenetic data.

Link: https://t.co/McBq5nZgwr

[SciePro @SciePro]

Experience the skull and brain anatomy like never before! Our exploded view animation dissects each part for detailed study.

Perfect for #MedEd and professional use. Visit https://t.co/QAcRyJL3jz

#AnatomyInMotion #SciePro #anatomy #physio #neurology #skull #meded #science #3d #sciart #medical #med

[Wenliang Wang @wenliang272]

We are thrilled to release our manuscript titled "Human Immune Cells Epigenomic Signatures in Response to Infectious Diseases and Chemical Exposures", which was led by my colleague @h_manoj and me. https://t.co/lE5yzHdfjg

[Yong-Xin Liu @YongXinLiu7]

iMeta | PyComplexHeatmap: A Python package to visualize multimodal genomics data @iMetaScience @Innov_Medicine @wileyinresearch https://t.co/d1ysa42mv0 https://t.co/uwpfSGYyzw

[Wubin Ding @DingWubin]

Check out these example outputs generated by PyComplexHeatmap:

[Wubin Ding @DingWubin]

Looking to create a Complex Heatmap using Python? Look no further than PyComplexHeatmap, a handy tool available at:https://t.co/iniOY8vQ7s. Now you don't have to switch between Python and R for machine learning or single-cell data analysis projects.

[Wubin Ding @DingWubin]

Our paper has been published on iMeta. Access it here: https://t.co/JPnPuFnc6X

[Wubin Ding @DingWubin]

Looking for user-friendly documentation? Check our comprehensive site at: https://t.co/lDMj8Zk9bt. It's packed with helpful resources to assist you with PyComplexHeatmap.

[Wubin Ding @DingWubin]

@iMetaScience @wileymicrobio @wileyinresearch @WileyBiomedical Link on the Github: https://t.co/iniOY8vQ7s

[iMeta @iMetaScience]

PyComplexHeatmap: A Python package to visualize multimodal genomics data
https://t.co/OXTFXWpCZi
#Bioinformatics #Python #ComplexHeatmap #Heatmap #visualization #DataScience
@wileymicrobio @wileyinresearch @WileyBiomedical

[Wubin Ding @DingWubin]

@UCSanDiego Hello. @UCSanDiego Two months ago, my wife applied for a job (RESEARCH DATA ANALYST 4/STATISTICIAN - 121959). But there has yet to be a response. Could you please tell us the recruiter so we can send an email to query the application status?

[Wubin Ding @DingWubin]

@jokergoo_gu Take good care of yourself.

[Wubin Ding @DingWubin]

@tangming2005 Thanks for your attention. I am the one who developed PyComplexHeatmap. Please give me some feedback after trying it.

[Wubin Ding @DingWubin]

@jokergoo_gu Thank you, Zuguang. I will keep updating it.

[Wubin Ding @DingWubin]

@gmorales85 @jokergoo_gu @YongXinLiu7 @iMetaScience Please give me some feedback about this package after you try it.

[Wubin Ding @DingWubin]

@krassowski_m @jokergoo_gu @lgautier You can try the python version of ComplexHeatmap. Recently, I developed a python version of ComplexHeatmap, named PyComplexHeatmap: https://t.co/iniOY8vihU