🆕target🎯identified for the treatment of childhood #leukemia. Research team👩🏼🔬👨🏿🔬 led by Prof. Jan-Henning Klusmann @JHKlusmann@JhKmann from LOEWE-@FCI_health discovers gene🧬essential for the growth of leukemia cells➡️https://t.co/wfimV3ejOy @goetheuni@mpi_hlr@UK_Frankfurt
Researchers have developed a strategy to deliver #mRNA directly into bone marrow stem cells where it can edit genetic defects and help repopulate the bone marrow with healthy blood cells.
Learn more ⬇️
📄: https://t.co/umJEIySWd4
#SciencePerspective: https://t.co/z1mhDoGwTb
Online Now: Yvas @UniofOxford, Heckl Klusmann & co. perform genetic and functional analyses to uncover mechanisms of progression of myeloid preleukemia to myeloid leukemia in children with Down syndrome. https://t.co/kOOe4znmAR
and providing a general approach to study transformation from a precancerous lesion. Huge thanks to: Klusmann lab,@dirkheckl lab, Roberts lab,Constantinescu lab,@PapaemmanuilLab,Peter Campbell, I-BFM, COG and Japan. International collaboration wins; an tonic in uncertain times.
Mechanisms of Progression of Myeloid Preleukemia to Transformed Myeloi... https://t.co/8EGZFtNw1o
Finally, our work on TAM to ML-DS trasition is out #CancerCell
Our new #CRISPR sgRNA on-target prediction CRISPRater is out (https://t.co/7fLJOOJTnE). Combined with off-target prediction in #CCTop#sgRNA design is as easy as it could be. Have fun and good luck for your #GenomeEditing experiments!