djreed

partner engineering lead @ youtube, part time small biz owner

[djreed @djreed]

@LocasaleLab @akoz33 Weird take. We should want to hear from experts of all fields on what they view as the potential limits of current technology. She also didn’t contradict anything you said here.

[Ihtesham Ali @ihtesham2005]

Jennifer Doudna won the Nobel Prize for gene editing and went on Bloomberg to say the chatbots everyone is betting on cannot innovate at all. Every promise Silicon Valley is making about AI curing disease just hit the one person qualified to check it.

She has spent her whole career inside the actual frontier of curing disease.

So when she talks about what AI can and cannot do in biology, she is not guessing. She is reporting from inside the lab.

Her words were blunt. She is not seeing chatbots innovate. They summarize data. They write reports. They do not come up with a brand new idea nobody has ever had.

Then the interviewer pushed. So you're saying AI can't innovate?

Doudna did not flinch. She does not know if it can't. She just does not see it doing it right now.

This lands harder when you remember who is making the opposite case. Sam Altman says AI will eliminate disease within five years. Larry Ellison says AI will cure cancer in a 48 hour window.

An OpenAI executive even floated that the company should get a cut of sales on any drug discovered through ChatGPT. Doudna answered that in two words. Good luck.

Even the cancer specialists Altman is selling to keep warning that cancer is not one disease but hundreds, each needing its own cure, and that compute does not skip the years of lab work.

Her reason is simpler. Biology is hard. You cannot simulate your way to an understanding of the human body.

The people promising cures are the ones selling the tool.

The person who actually won a Nobel building them is telling you it has not happened yet.

Source: Bloomberg Originals

Watch the full video on their official channel.

[djreed @djreed]

@aubrey_huff @sfchronicle @MLB My (now husband) and I love the Giants! We've been going to games for decades, and have always felt welcomed! We love Bay Area sports. 2 years ago, I got my dad 49ers season tickets for Father's Day so we could spend time together. Our son joined his first tailgate this year!

[djreed @djreed]

Nixon literally recorded himself using his office to obstruct the investigation, conceal evidence, and protect the people involved.

He resigned under bipartisan pressure.

[Aaron Rupar @atrupar]

JD Vance: "I think Nixon's historical legacy is enjoying a bit of a renaissance, and deservedly so. I joked that if Watergate happened tomorrow, it would be like a 12 hours news story. The idea that it took down a presidency is crazy."

[djreed @djreed]

“Without human direction, you have compute running in circles.
This means the real opportunity is not in picking the best model but instead in building a learning loop on top of models where human capital and token capital compound.”

[Satya Nadella @satyanadella]

https://t.co/vLmiBKTtX3

[NOBUNAGA🇯🇵🏯_夏樹蒼依 @japan_nobunaga]

USA. A Mexican restaurant. We had not yet ordered anything, and the food was already arriving.

Chips. Salsa. Unrequested. Free.

I stopped the waiter. "We have not earned these."

"They just come with the table, man."

They come with the TABLE. In my land, hospitality is a debt. Every gift creates an obligation, weighed carefully, returned in the proper season with interest of feeling. Here, the gift arrives before you have even proven you can pay for dinner.

This is not an appetizer. This is a declaration: we trust you. Eat.

I ate with the gravity the moment deserved. And then — I must report this calmly — the basket emptied, and a new one appeared.

"Did we…?"

"Refill," the waiter said. "It's bottomless."

Bottomless. They have wells of salsa. The supply lines of this nation are beyond anything my ancestors imagined.

My friend warned me. "Don't fill up on chips, dude."

Too late. I had accepted three baskets. Honor demanded each one be finished — an unfinished gift is an insult. By the time my actual food arrived, I was a ruined man.

I was not hungry. I was not comfortable. I had been defeated by a courtesy.

Generosity that arrives before the request cannot be repaid. It can only be survived.

I know the rule now. I have made my peace with the basket. One basket. Two at the most.

Who am I deceiving. There is no number of baskets I would refuse. The trust of a nation is in that salsa, and I intend to honor all of it.

[Swaggy Unc, IQ 267 @swaggyunc]

Eating in Mexico coming from England or Scotland has got to be a transcendent experience. Like seeing colors for the first time

[Anne Applebaum @anneapplebaum]

Amazing: KPMG wrote a report describing the successful use of AI by businesses. But the case studies turned out to be AI hallucinations.
https://t.co/s3LE8vedNi

[djreed @djreed]

@giveashitnature daddy longlegs can also refer to cellar spiders, very common around here. they’re true spiders, can bite (but are docile and do rarely). definitely not the most venomous spider (less potent than a bee sting).

[djreed @djreed]

@avstorm It looks like it’s installing on ios. No hate here, just caused confusion. Would think designers might care about that.

[djreed @djreed]

@stevy_smith @farzyness same

[djreed @djreed]

@JamesTate121 But the hard part is passing a law…

[djreed @djreed]

@full_kelly_ @SpiritAirlines This. It’s a huge loss actually.

[djreed @djreed]

@fractal_friend Not universally.

[djreed @djreed]

8/
Companies that treat this as a headcount reduction exercise, especially at the senior level, will look back on it as a major strategic error.

[djreed @djreed]

1/n Prediction: The current corporate reaction to AI is backwards.

[djreed @djreed]

7/
The smartest companies will lean into this by:

• Upskilling teams to use AI effectively
• Maintaining or growing headcount to use the increased capacity
• Protecting senior talent who guide systems, architecture, and strategy