Creating human cells having 100Mb genome, 1/30 of the natural human genome. In this journey, I encounter many mysteries and new discoveries. Go together!
How much of the human genome is essential?
Two pieces out today from our lab: 1) a method to map essential genomic intervals at gigabase scale, and 2) an argument that it's time to consider synthesizing a minimal human genome.
https://t.co/iwyiZXKGdp
https://t.co/izJ2DzhgQC
This new review paper from Chris Voigt's lab is a must-read for #synbio researchers and investors. His keynote at #SEED2024 contained a lot of the case studies and thinking in this paper.
Systems and Methods for Continuous Evolution of Enzymes
"we summarize the working mechanisms of recently developed continuous evolution strategies, discuss examples of their applications focusing on enzyme evolution"
https://t.co/0xyFP198Kj