Dominic Kaul

Stress(ed) Researcher | | Previously obsessed with glia | All opinions are my own 🧠

[Dominic Kaul @domkaul]

[1/6] Buckle in for the story of a big chunk of my PhD: In our recent preprint, we explore the molecular impact of severe stress on the human brain. A thread:

[Dominic Kaul @domkaul]

A moment that felt both like it came all too quickly and was also long overdue. Thanks to everyone for the support along the way especially the @mindbehindMINDS gang❤️

[mindsbehindtheMINDS @mindbehindMINDS]

SQUAD 🔥

[Dominic Kaul @domkaul]

Bittersweet to close this chapter and say farewell to glia for now ❤️

[Max Planck Institute of Psychiatry @mpi_psychiatry]

Exciting new results from single nucleus RNA sequencing of 800,000 nuclei from 90 post mortem brain samples showing converging effects of ageing and #Alzheimer disease and other #psychiatric disorders.👇https://t.co/NriayHyzLj

[Mitchell St Clair-Glover @stem_mitch]

Thrilled to share the first major publication from my thesis, huge thanks to all who were involved! If you’re interested in neural bioprinting, check out our open access manuscript below 👇

[Dominic Kaul @domkaul]

@natalie_matosin Very much full circle! And onto new beginnings

[Dominic Kaul @domkaul]

[7/6] If you’re interested in reading more on this, check out the preprint here!: https://t.co/uVtRJ6SdeK

[Dominic Kaul @domkaul]

[1/6] Buckle in for the story of a big chunk of my PhD: In our recent preprint, we explore the molecular impact of severe stress on the human brain. A thread:

[Dominic Kaul @domkaul]

[6/6] Finally, we wanted to see whether human astrocytes could directly respond to stress. We activated cortisol receptors in hPSC astrocytes. Activation directly shaped the glutamate clearance and the calcium response to excitatory neurotransmitters, such as glutamate and NMDA.

[Dominic Kaul @domkaul]

@DrCriCru @natalie_matosin Thanks Cristiana!

[Dominic Kaul @domkaul]

@JPablo_Neuro @natalie_matosin Thanks Pablo!

[Juan Pablo Lopez @JPablo_Neuro]

Congratulations @domkaul, @natalie_matosin and team on this beautiful story!

[Cristiana Cruceanu @DrCriCru]

Fantastic preprint out from the great lab of @natalie_matosin led by the very talented @domkaul. Congrats to all the authors for this beautiful work. A great read for anyone interested in glial biology and the role these fascinating cells play in stress.

[Dominic Kaul @domkaul]

More than excited to finally have this story on my favourite cells out! An enormous thank you to everyone involved.

[Dominic Kaul @domkaul]

I can't say enough positive words about this opportunity. Great people, great vibes, great science - what more could you want!

[Dominic Kaul @domkaul]

@debs_sophie @natalie_matosin @mindbehindMINDS @NeuralOoi Thanks Sophie!

[Dominic Kaul @domkaul]

Beyond excited to have finally submitted my thesis!!!!! A huge thank you to everyone who has helped me out along the way especially @natalie_matosin, the lab @mindbehindMINDS, @NeuralOoi, Sibylle and Naguib for all your support