Dr. Sachin Hingmire

Medical Oncologist at Deenanath Mangeshkar Hospital. pune, India. Emeritus Editor South Asian Journal of Cancer (SAJC)

[Supreeth @Supreeth_medonc]

Third one in the #Clinicalpearlsinoncology series. Today let's understand pseudo-AKI in Oncology, which is a very common yet under-discussed issue. I'm using a couple of cases I came across in my practice to walk us through the concept.

#CPOseries
#PseudoAKI
#Oncology
#NSCLC

[Dr. Sachin Hingmire @dr_hingmire]

https://t.co/Z0BGxkJNh4

[Dr. Sachin Hingmire @dr_hingmire]

https://t.co/GPtXJ5pwCP

[Dr. Sachin Hingmire @dr_hingmire]

Clinical Oncology Pearl

Not all metastatic prostate cancers with a normal PSA are androgen receptor (AR)-independent.

Recently reflected on two patients with metastatic high-grade prostate carcinoma and disproportionately LOW / NORMAL PSA levels—one with neuroendocrine differentiation and the other without.

Both achieved >6 years of progression-free survival following initial platinum-based chemotherapy, radiotherapy to the primary prostatic mass, and CONTINUED ADT.

Take-home message:

AR signaling may remain an important driver even in PSA-low/normal aggressive variant prostate cancer.

Sometimes the biology is more hormone-sensitive than the PSA would have us believe!

#ProstateCancer #GUOncology #UroOncology #MedTwitter

[Dr. Sachin Hingmire @dr_hingmire]

Clinical Oncology Pearl

A patient presents with breathlessness shortly after Cycle 1 of dual immune checkpoint inhibitor therapy.

Troponin-T is positive.

The immediate reflex may be ACS.

Pause and consider another important differential:

Myocarditis + myositis + myasthenia gravis overlap syndrome, a rare but potentially life-threatening immune-related adverse event.

Early recognition can be critical.

#Immunotherapy #Oncology #ClinicalPearls

[Dr. Sachin Hingmire @dr_hingmire]

Why do we practice medicine…Dr Dhananjay Kelkar shares his perspective…Best ever!

[Dr. Sachin Hingmire @dr_hingmire]

Higher access to Pertuzumab and TDM1 Her2 positive MBC with availability of low cost biosimilars … options beyond Trastuzumab Pertuzumab and TDM1

[Dr. Sachin Hingmire @dr_hingmire]

Classical radiological signs for 5 FU leukoencephalopathy… complete resolution and no recurrence with substituted capecitabine

[Dr. Sachin Hingmire @dr_hingmire]

It’s high time that we learn the complex interaction between insulin, glucose metabolism and pathogenesis of cancer

How many of us have seen a patient of insulin deficient/dependent diabetes ( IDDM) suffering from cancer…? ( At least none in my experience of 15 years )

[Dr. Sachin Hingmire @dr_hingmire]

Is PDL1 negativity a poor prognostic marker in TNBC?
In KN 522- Path CR rates appear to be significantly lower in PDL1 negative population as against PDL1 positive patients, both in chemotherapy only arm and Pembro arm.

[Dr. Sachin Hingmire @dr_hingmire]

Simplifying IO in esophageal, GE junction and gastric cancers

[South Asian Journal Of Cancer @sajconline]

https://t.co/Vrte2g5l2X

The new issue of SAJC is online.

Let us know which are your favourite articles of the issue 👍🏽

[South Asian Journal Of Cancer @sajconline]

Welcome New Associate Editors to SAJC.
Seven ⭐ s !!
@ShankarAbhishek
@lingarajnayak @ChowdaryStalin
@groundhogcs
@drsayanradonco
@NirmalyaDP
@pankajpanda86

Proud to have you on @sajconline Editorial board👏👏
@purvish1
@dr_hingmire
@onconikhil @sujithonco

[South Asian Journal Of Cancer @sajconline]

DM @sajconline @sujithonco to let us know your field of interest and if you are willing to be part of our esteemed reviewer panel.

Science knows no boundaries of nation and neither our panel has.

Clinicians esp from SAARC countries are very welcome 🙏🏼

#GLOBALONCOLOGY

[South Asian Journal Of Cancer @sajconline]

Being a Reviewer !

Some say, it is thankless job. Some say, takes too much of time.

But, those who are in research and are fascinated by science, love to know what's happening much more before others read and play a major role in enhancing scientific worth of article

Join us

[South Asian Journal Of Cancer @sajconline]

The latest issue of SAJC is all inclusive on COVID .

This epidemic has not left any dimensions of science and life untouched.

We present the latest guidelines and data , specific to COVID and Cancer pertaining to India and SAARC countries

https://t.co/Vrte2g5l2X

@dr_hingmire

[South Asian Journal Of Cancer @sajconline]

#ASCO2021 abstracts from India 🇮🇳 and all other SAARC countries 🇧🇩🇵🇰🇳🇵 in a single thread..

Captures the essence of the local need , the solutions and the goals ahead.
Happy reading 🙏

[South Asian Journal Of Cancer @sajconline]

SAJC indexed in Pubmed has the archives listed on Pubmed Central for review

Please 👇 the link below for journal issues from 2012 to 2020

@purvish1 @dr_hingmire
@PSKulkarni
@VanitaNoronha @venkymd
@MaheshSambhus
@TPSahoo1
@OncomedR
@sujithonco

https://t.co/5XKchjN1AM

[South Asian Journal Of Cancer @sajconline]

The New Avatar of SAJC -
Editorial in Dec 2020😊
@dr_hingmire
@purvish1

https://t.co/XeA0RpSxXZ

[docyogi @docyogi1]

Shared with permission. Imagine yourself in a chemotherapy day care ward for your chemo cycle. How would you keep yourself engaged? My good friend @dr_hingmire found his patient creating something very beautiful. Sometimes we learn a lot from these bravehearts ! #lifeisbeautiful