Amani Mohsen

[Michael Albert, MD @MichaelAlbertMD]

I had a patient last month who did everything right. 60 lbs down on tirzepatide. A1c from 6.4 to 5.3.

She told me: "I'm scared my body is just waiting to take it all back."
Six new papers just proved her right.

Weight regain isn't moral failure. It's cellular memory.

[Reads with Ravi @readswithravi]

15 books recommended by Daniel Kahneman:

1) Nudge by Richard H. Thaler and Cass R. Sunstein

[Amani Mohsen @dramohsen]

@Realjabulanijnr @Mary_ork Yes done
Available on kindle unlimited for free to read
https://t.co/6l1Hv1CwBe

[Reads with Ravi @readswithravi]

Reading 10 pages a day = 3,650 pages a year.

That’s about 10–12 books a year.

Schedule time for reading and learning in your daily routine.

[Words of Wise | Mindset Coach @Wordofwise_]

“If you're brave enough to say goodbye, life will reward you with a new hello.”

— Paulo Coelho

[Reads with Ravi @readswithravi]

“It’s impossible to live without failing at something, unless you live so cautiously you might as well not have lived at all.”

— J.K. Rowling

[James Anthony 💎 @JamesMartirq7p]

“One beautiful heart is better than a thousand beautiful faces." ~William Shakespeare

[Alex & Books 📚 @AlexAndBooks_]

Brian Tracy on how to change your life:

"Get up early enough to read for 30-60 minutes in something that is motivational, something that is inspirational, something that is educational. Something that uplifts your mind, what we call mental protein."

[Alex & Books 📚 @AlexAndBooks_]

Learning how @naval reads books will permanently change the way you read:

[Yash @DoctorBhavsar]

HbA1c is not used for diagnosing gestational diabetes 🤔‼️

Why ?

Because in a pregnant individual the A1c levels you are going to get NOW, i.e. at screening time (2nd trimester ~ 24th week gestation) are reflective of almost 10-12 week ago.

It does not reflect CURRENT ongoing effects from HPL hormone, progesterone and cortisol — the notorious trio to induce insulin resistance and gestational DM in an effort to provide more glucose to baby 👶🏻🍼

So what should i use that has higher sensitivity and specificity in this case ?

Answer is — oral glucose tolerance test

OGTT at 24-28 weeks is recommended as the best test to rule in or out gestational diabetes

Get the patient come in fasting — give 75 grams of PO glucose and then, measure BSG 1 and 2 hr mark, and diagnoses is made if any if the following happens :

— Fasting BSG > 92
— 1 hr > 180
— 2 hr > 153

#MedTwitter #MedX #Endocrinology

[Amani Mohsen @dramohsen]

@kiragriffoo Hi

[Amani Mohsen @dramohsen]

@Andrew_Baltasar Thank you so much. I will consider the revvue lubrary.

[Amani Mohsen @dramohsen]

@Andrew_Baltasar Thank you so much. I have joined many facebook groups for ARCs without answers. Any link would you suggest?

[CME INDIA @CMEINDIA1]

New ACC/AHA Lipid Guidelines 2026 — Practice-Changing Insights:At a glance..
📌 Core Philosophy

“Lower LDL-C, earlier and for longer → better lifetime ASCVD reduction.”

🔬 1. Start Early – Think Lifetime Risk

Lipid screening should begin at ≥19 years, with repeat every 5 years or earlier in high-risk individuals.
Statin therapy can be initiated as early as 30 years if LDL-C ≥160 mg/dL, strong family history, or high 30-year risk—even if 10-year risk is low.
🎙️Key shift: Move from “10-year risk” to lifetime cumulative exposure model

🧮 2. PREVENT Risk Calculator Replaces PCE

New AHA PREVENT tool improves ASCVD risk prediction and starts risk estimation from age 30.
Includes 30-year risk estimation, crucial for younger patients.

📊 3. Recalibrated Risk Categories

Low: <3%

Borderline: 3–5%

Intermediate: 5–10%

High: ≥10%

👉 Clinical implication: Statins now justified at lower thresholds (≥5%)

🎯 4. LDL-C Targets Are Back

<100 mg/dL → Low/intermediate risk

<70 mg/dL → High risk

<55 mg/dL → Established ASCVD

👉 Shift: From % reduction → absolute target-driven therapy

🧬 5. Universal Lp(a) Testing

One-time Lp(a) measurement for ALL patients is now recommended.

≥125 nmol/L → ↑ ASCVD risk

≥250 nmol/L → ~2× risk

≥430 nmol/L → ~4× risk

👉 Intensify LDL lowering even if Lp(a) cannot yet be directly treated

🧪 6. ApoB & CAC — Precision Risk Tools

ApoB reflects total atherogenic particle burden and helps detect residual risk.
CAC score acts as “tiebreaker” in borderline/intermediate risk.

⚠️ 7. Expanded Risk Enhancers

Now includes:

PCOS, early menopause, adverse pregnancy outcomes

South Asian and Filipino ethnicity

CKM syndrome, inflammation markers

👉 Clinical message: Take detailed reproductive & ethnic history seriously

🩺 8. Special Populations – Stronger Statin Mandate

All patients (40–75 yrs) with:

CKD stage 3–4

HIV infection

→ Should receive statins irrespective of LDL-C

🍔 9. Triglycerides – Lifestyle First

Statins remain foundational even in hypertriglyceridemia.
Refer to dietitians if TG ≥150–1000 mg/dL with CKM features.

💊 10. Supplements – Clear Negative Recommendation

Non-prescription supplements (e.g., fish oil) are NOT recommended for ASCVD risk reduction due to lack of benefit.

🔥 CME INDIA Take-Home Messages

Atherosclerosis begins early → intervene early

LDL exposure = cumulative toxin → duration matters as much as level

Lp(a) is now a universal risk marker, not optional

Risk assessment is shifting from short-term to lifetime biology

Precision lipidology = LDL-C + ApoB + Lp(a) + CAC

🏷️

“From numbers to lifetime exposure: Lipidology has entered the era of precision prevention.”

https://t.co/HU2Fcucaf3

[Amani Mohsen @dramohsen]

@Sylvia147225911 Here is an early access free copy of my new parable, The Sages of the Hidden Road: https://t.co/RviiEBLv7d
If you do enjoy the read, I would be incredibly grateful if you could share your thoughts via a review on Goodreads and Amazon (on 11 May).

[Amani Mohsen @dramohsen]

@Zuliovna @RuthSummie Would you like to share some few words about the novel ...your honest thoughts ...even by private msg ...i would like to hear from you.

[Nutrition Science @NutrioSci]

🎯NICE guideline 2026

Type 2 diabetes in adults: management