Anand Rohatgi

[Anand Rohatgi @dranandrohatgi]

Happy 50th to my best friend and life partner, @DrMatulevicius!! You're the most amazing person I've ever met, and I hope to celebrate many more birthdays with you! 50 and absolutely fabulous! A smattering of memories: https://t.co/EfNA2AuKYr

[South Asian Public Health Association (SAPHA) @SAPHAinfo]

February is American Heart Health Month, and we wanted to spread awareness about why this is so important in our community! Check out https://t.co/Gyi90TknoU and explore our resources and efforts to strengthen South Asian heart health! #PublicHealth #HeartHealthMonth #SAPHA

[Anand Rohatgi @dranandrohatgi]

Pakistan was the only #SouthAsian country where mortality from ischemic #heart disease was higher in #women vs. men. Intriguing! #Sex Disparities in Ischemic Heart Disease in South Asia: The Role of Dietary Factors | JACC: Asia https://t.co/1BQP5O9fEg

[Amit Khera @dramitkhera]

Our @utswheart #Prevention family celebrating with lead author Ann Marie Navar for the practice changing trial in @NEJM today- oral #PCSK9 inhibitor for potent LDL-C lowering https://t.co/kjinsEIQLn

[UTSW Heart @utswheart]

Thank you to everyone who joined us across the UT Southwestern campus for #WearRedDay! Stay tuned for more updates from the Heart and Vascular team throughout heart month. #GoRedForWomen

[Anand Rohatgi @dranandrohatgi]

Oral PCSK9 inhibitor is a total game changer for prevention! Congrats to esteemed colleague @utswheart Dr. Ann Marie Navar for her first author publication in @NEJM!! Enlicitide | New England Journal of Medicine https://t.co/IPp3CoLE2C

[Sonu Abraham, MD, FACC @SonuAbrahamMD]

4/ 💡 Clinical Implications
In HT pts:
Alirocumab = safe & powerful LDL-C lowering 
Short-term plaque impact unclear 
Possible reasons: low baseline LDL, inflammation-driven CAV, potent statins used
Longer follow-up may be required

#SoMeEditor @CircAHA

[Sonu Abraham, MD, FACC @SonuAbrahamMD]

2/ 📊 Trial Design
114 HT recipients: 57 alirocumab vs 57 placebo
All on rosuvastatin 
Invasive coronary assessment at baseline & 1 yr:
• angiography, NIRS-IVUS 
• FFR, CFR, IMR 
Primary endpoint: change in plaque volume

#SoMeEditor @CircAHA

[Sonu Abraham, MD, FACC @SonuAbrahamMD]

3/ Key Findings
LDL-C dropped: 73 → 32 mg/dL 💪
Total cholesterol, ApoB, Lp(a) ↓
No significant effect on: plaque volume, coronary physiology 
Well-tolerated ✅

[Sonu Abraham, MD, FACC @SonuAbrahamMD]

1/ 🚨 Cardiac Allograft Vasculopathy Inhibition with Alirocumab: The CAVIAR Trial
Tested early after heart transplant to see if alirocumab could slow plaque buildup while safely lowering LDL-C. 🧵👇
#AHA25 #SimPub @CircAHA #OHT #PCSK9 #CAV https://t.co/wpk4N31i8K

[Circulation @CircAHA]

#AHA25 In the NOTIFY-PICTURE trial, notification of providers/patients of undergoing non-gated chest CT imaging found to have elevated CAC using an AI algorithm was assoc w/ inc. statin use https://t.co/o4lvlQgkN7
@ATSandhu
@Mastrodicasa_MD
@FaRodriguezMD
@SnehaShahJain

[Anand Rohatgi @dranandrohatgi]

Congrats to my #postdoc Dr. Anamika Gangwar @utswheart on her poster at @AHAMeetings AHA25.

[Anand Rohatgi @dranandrohatgi]

Genome-wide polygenic risk score in premature coronary artery disease in India https://t.co/NS27iJ2Ih0

[Anand Rohatgi @dranandrohatgi]

Great highlight by @ACCinTouch of our Clinical Practice Statement on #SouthAsian Cardiometabolic Health published in @ASPCardio - Clinical Practice Guidelines For Improving South Asian Cardiometabolic Health - American College of Cardiology https://t.co/nqdncy6sI0

[Anand Rohatgi @dranandrohatgi]

Ethnic Differences in HDL Quantity, Quality, and potential association... https://t.co/cwRvtChAWB

[Anand Rohatgi @dranandrohatgi]

Interesting study in @masala_study linking hepatic fat but not other fat depots to albuminuria in #SouthAsians: Associations of Adiposity with Albuminuria in South Asian... : Journal of the American Society of Nephrology https://t.co/kyYaWh2AYL

[Anand Rohatgi @dranandrohatgi]

Nice summary study of #genetic diversity in #SouthAsians: Human genetic diversity across South Asian populations: A... : Medicine https://t.co/agBLsVy4LM

[Anand Rohatgi @dranandrohatgi]

Wow! What a great @utswheart presence at #ASPC2025 in Boston this weekend! Helen Hobbs, Darren McGuire, Spencer Carter, and Ann Marie Navar! Congrats to CV fellow Danh Nguyen, and @UTSWInternalMed residents Jimin Hwang (chief), Gabrielle Schwab, and Khush Kharidia!! So proud!

[Anand Rohatgi @dranandrohatgi]

Great work by @AAgarwalaMD and colleagues on establishing CAC percentiles in #southasians: Sex-Specific Coronary Artery Calcium Percentiles Across South Asian Adults: Combined Analyses From MASALA and DILWALE | JACC: Advances https://t.co/4jwpeygNZz

[UT Southwestern Internal Medicine @UTSWInternalMed]

We congratulate Dr. Joshua Beckman on his Award of Meritorious Achievement from the American Heart Association! https://t.co/YVyTVYLELi