Our work presents the first cryo-ET image of the authentic #Mpox virus and its 3D reconstruction. It's a huge virus. Details in: https://t.co/oNvKCdsbQK
Our new work is online in PNAS today. In this work, electron-beam & PFA inactivated Delta virions were imaged by cryo-ET and compared; homotypic fusion were found between the virions. In situ architecture and membrane fusion of SARS-CoV-2 Delta variant https://t.co/WFHaRcSNJ2
@SystemsVirology We think it is spike related, because the other structural proteins have not mutated much. we proposed a self-fusion theory for the invagination formation (fig 5b), but are open for suggestions
Looking forward to speak at the International conference "#COVID19, Advances and Remaining Challenges", 29 Sep.-1 Oct. 2021, organised by @institutpasteur @PasteurVirology https://t.co/bEnqxiARnD
I draw Fig.1 to pay tribute to T.Baker and S.Fuller, two pioneer&masters in cryoEM structural virology. S.Fuller was a founder of OPIC @OxfordStrubi, which cultivated #cryoET virology, @BriggsGroup, Guilia and many younger #cryoET generations, including me
https://t.co/8OdzSWHL24
My review is online today on @TrendsBiochem, highlighting the recent advances in in-situ structural virology and cryo-ET method developments. The efforts shed light on the assembly and intracellular activities for some most threatening viruses. https://t.co/8OdzSWHL24
@bengeliscious Hi Ben, 3 hours from the city. Only a fraction of great wall was restored, most, like this piece, were aged. The aged Walls are mostly built on very steep mountains, climbing it is like climbing a cliff