Exciting progress in BCG-unresponsive NMIBC. Our @TheLancetOncol commentary explores the promise of cretostimogene, balancing impressive durability and safety data with the key questions that still need answers.
https://t.co/UhOKACeUJE
EV-302 reshaped the landscape of metastatic urothelial carcinoma.
However, two critical methodological aspects warranted deeper scrutiny and were addressed in our recent paper:
https://t.co/nR2JD6RRE4
Most retrospective studies comparing trimodal therapy and radical cystectomy are at high risk of informative censoring a bias that can artificially favor one treatment over another. @CHematology@ChristianRolfo@OncoAlert
https://t.co/HI0hcXAuGl
🔬 Our latest study dives into laser lithotripsy with a novel in-vitro setup to explore thermal effects. Using a glass pipette model of a renal calyx, we measured temperature changes and thermal doses under varied conditions. #UrologyResearch#MedicalInnovation
📊 Results are in: Higher laser power correlates with increased thermal risk. Maintaining a 'thermal safety distance' effectively reduces the likelihood of tissue damage. Recommended power: ≤10W in the ureter, ≤20W in the kidney with irrigation. #Urology#PatientSafety
🌡️ By integrating thermal camera images and the Sapareto-Dewey formula, we quantified the safe distances from laser fiber to prevent tissue damage. #Thermalsafety#Urology