Matthew Stanbrook

Deputy Editor @CMAJ, Associate Professor @uoftmedicine, Respirologist @UHN, Affiliate Scientist @ICESOntario, dad of 2 amazing kids

[Matthew Stanbrook @drstanbrook]

@BukolaKSalami @PHAC_GC @WAGE_FEGC @JusticeCanadaEN @cityofcalgary @SSHRC_CRSH Congratulations Bukola!

[Matthew Stanbrook @drstanbrook]

@riyadlehebi In phase 2, they were looking at all COPD to see if tezepelumab needed to be targeted or not. Answer is it does - if it really works in COPD at all, which remains to be proven in phase 3, but signal from COURSE is interesting

[Matthew Stanbrook @drstanbrook]

Phase 2 COURSE study just presented at #ATS2024 by Dave Singh @OfficialUoM: tezepelumab did not significantly reduce #COPD exacerbations overall, but trends suggested greater benefits in those with higher Th2 inflammation. Suggests phase 3 study should target this population.

[Matthew Stanbrook @drstanbrook]

NOTUS trial just presented at #ATS2024 by @suryapbhatt @uabmedicine and published @NEJM: dupilumab reduced exacerbations by 1/3 in #COPD patients with eosinophils >300. Confirms prior BOREAS trial results.

[Matthew Stanbrook @drstanbrook]

ARISE study just presented at #ATS by @CLDaleyMD @NJHealth: liposomal amikacin as add-on to azithromycin + ethambutol was more likely to achieve microbiological clearance of MAC lung disease at 6 months. Also validated QOL-B RD as a PRO measure in MAC.

[Matthew Stanbrook @drstanbrook]

Huge congrats to Andrea Gershon @uoftmedicine, recipient of the @ATS_BSHSR Lifetime Achievement Award at #ATS2024!

[Matthew Stanbrook @drstanbrook]

Dmitry Rosenberg @uoftmedicine presenting pilot RCT of cognitive-physical home-based pulmonary rehabilitation right now at #ATS2024. Proud to be collaborating with him on this!

[Mindaugas Galvosas, MD @MGalvosas]

🚨@US_FDA stresses at the #ATS2024 session - there is NO technology/device cleared by the agency for counting coughs. The VitaloJAK system mentioned in the presentation is only cleared for audio recording, and NOT for cough counting.

[Matthew Stanbrook @drstanbrook]

Shows we need a nuanced approach in thinking about how to ensure equity for lung disease patients while considering the implications of practice changes

[Matthew Stanbrook @drstanbrook]

New study of implications of eliminating race adjustment in PFT equations just presented at #ATS2024 by @JamesADiao: race-neutral interpretation reclassified millions of patients with implications on work, disability eligibility and transplant priority but not clinical outcomes

[Matthew Stanbrook @drstanbrook]

BICS trial just presented at #ATS2024 by @doclip1 and published @JAMA_current: bisoprolol did not reduce exacerbations in GOLD E #COPD, but did not cause harm either. We should give beta blockers to COPD patients with cardiovascular indications but it won’t help their COPD

[Matthew Stanbrook @drstanbrook]

BEACON study just presented at #ATS2024 by Jadwiga Wedzicha @imperial_SoM: CT scans can find evidence of early #COPD in young smokers 30-45

[Matthew Stanbrook @drstanbrook]

UCAP study just presented at #ATS2024 bu Shawn Aaron @uOttawaMed and published @NEJM: case-finding and subspecialist treatment of asthma and COPD reduced healthcare utilization by half and improved quality of life and lung function. We need to find these patients!

[Matthew Stanbrook @drstanbrook]

ZEPHYRUS-1 just presented at #ATS2024 and published @JAMA_current: pamrevlumab did not slow FVC decline in #IPF. Disappointing that yet another biologic for IPF has failed

[Toronto Maple Leafs @MapleLeafs]

A moment for you, Leafs Nation! 👏

⭐️ 1 Retweet = 2 Votes Each ⭐️
#NHLAllStarVote John Tavares
#NHLAllStarVote Morgan Rielly
#NHLAllStarVote Mitch Marner
#NHLAllStarVote William Nylander
#NHLAllStarVote Leafs Nation 💙

[Matthew Stanbrook @drstanbrook]

How can Canada’s health systems improve care for people with chronic obstructive pulmonary disease? New commentary by ⁦@ablazermd⁩ and me ⁦@CMAJ⁩ https://t.co/e9GmRNN3xE

[Matthew Stanbrook @drstanbrook]

Our latest editorial: A new policy on the use of artificial intelligence tools for manuscripts submitted to ⁦@CMAJ⁩ https://t.co/bajq7qA0nh

[Matthew Stanbrook @drstanbrook]

@docschull @CMAJ @BukolaKSalami @hdrn_rrds @IPDLN @ICESOntario Thanks Mike! We look forward to continuing to feature @ICESOntario’s outstanding research in this area

[Matthew Stanbrook @drstanbrook]

@geetamehta0 @CMAJ @CCctg Great to see @CCCTG’s commitment to this, Geeta! Hope you will think of @CMAJ as a home for some of your excellent work

[Matthew Stanbrook @drstanbrook]

CMAJ has a new policy to encourage and standardize reporting of race and ethnicity in health research - check it out ⁦@CMAJ⁩ ! https://t.co/Z6YEMi94gr