Dr Emma-Jane Mallas

Cognitive Neuroscientist • Postdoctoral Researcher @ImperialCollege @UKDRI

[Dr Emma-Jane Mallas @e_mallas]

🚨New fMRI paper out in @Brain1878 🧠 We show that methylphenidate alters corticostriatal network function in TBI patients, increasing caudate-ACC connectivity while decreasing caudate-DMN connectivity. https://t.co/thw9LmBrKG @Neurosharp @nialljbourke @michaelcbdavid

[Michael David @michaelcbdavid]

🧠 Our new paper!
We show brain state entropy—derived from dynamic resting-state fMRI—captures the loss of network flexibility after traumatic brain injury.
It reflects injury severity, is profoundly affected by propofol sedation, and predicts recovery.

https://t.co/buu5fDYjqN

[Michael David @michaelcbdavid]

A chapter of my PhD has now been published in @braincomms "Pupil-linked arousal, cortical activity, and cognition in Alzheimer’s disease".

https://t.co/BHNyxwcgyy

Quick 🧵 on what we found.

@PareshMalhotra @Neurosharp @NeuroDocLucia @peterjlally @e_mallas

[Brain @Brain1878]

Mallas and De Simoni et al. show that methylphenidate modulates connectivity between the caudate nucleus and large-scale brain networks after traumatic brain injury, and propose that this may be the mechanism by which the drug enhances cognitive function. https://t.co/Ucx2XXy9N6

[Charlotte Luff @CharlotteLuff]

Happy to share our paper, out this week in Cell Reports. We show that a neuron can act as a frequency mixer, and describe a new method for detecting higher-order frequency mixing interactions in brain activity. Always a pleasure to work with @RobertPeach15

[Dr. Maria Balaet @emmsskyyy]

New publication alert!

Check out the whole paper published in @eClinicalMed here: https://t.co/lv9Y2syF8J

Really excited to share this piece of work which has been in the making for many years. It was an immense collaborative effort between clinicians, psychologists and neuroscientists, and also one of the core projects I contributed to since my early days at Imperial College.

We present an observational study where we use our bespoke computerised cognitive testing tasks to assess cognition in a traumatic brain injury (TBI) patient population.

We illustrate that online cognitive assessment of TBI patients is feasible, sensitive, and efficient. When combined with normative sociodemographic models and autogenerated reports, it has the potential to transform cognitive assessment in the healthcare setting.

Shout out to @ProfHampshire @Neurosharp & the entire team for the massive amount of work that went into this over the years!

[Michael David @michaelcbdavid]

Tireless effort by Martina and the team to get this paper out after years of work:

"Computerised cognitive assessment in patients with traumatic brain injury: an observational study of feasibility and sensitivity relative to established clinical scale"

https://t.co/8qDw7fV4k0

[Michael David @michaelcbdavid]

Our new paper on 'Remote Monitoring of Physiology in People Living With Dementia' published here!

https://t.co/FGqIs7PPeC

@UKDRI @Daniell19244313 @Neurosharp @PareshMalhotra @NeuroDocLucia

[Nikos Gorgoraptis @neurognosia]

A wonderfully eloquent article by the brilliant Greg Scott on how personal experience of a neurological condition can be positively transformational @PracticalNeurol https://t.co/trZUsVZ11h

[Dr Emma-Jane Mallas @e_mallas]

We show that this binding disruption occurs transiently during a period of #PTA and is associated with a shift towards lower frequency power on #EEG. These findings provide mechanistic insight into PTA and working memory binding failures following TBI.

[Dr Emma-Jane Mallas @e_mallas]

How do we remember what was where? New paper with @Neurosharp @neurognosia @So_Dautricourt @pertzov in @SfNJournals explores transient misbinding during a period of post-traumatic amnesia (#PTA) following traumatic brain injury (#TBI) https://t.co/TFtc3BZCrY

[Dr Emma-Jane Mallas @e_mallas]

Information about how an object appears and where it is in space must be bound together to form a complete representation in memory. The ability to bind the ‘what’ and the ‘where’ can be temporarily disrupted after #TBI and may be due to electrophysiological changes in the brain.

[Nikos Gorgoraptis @neurognosia]

New paper out on post-traumatic amnesia in #TBI in @sfnjournals #JNeurosci with @e_mallas @Neurosharp @pertzov @So_Dautricourt #GregScott https://t.co/MdZ0zEUjjq

[Alina-Irina Serban @alina_i_serban]

Our paper on “The effect of COVID-19 on the home behaviours of people affected by dementia” is now available to read in npj Digital Medicine. Thank you everyone who’s contributed to this paper.

[nahid zokaei @nzokaei]

We are now in the 4th week of protests in Iran. Despite the news fatigue we all may be feeling, here are some reason’s as to why I think this movement is different than those that came before (in Iran), and why they deserve our sustained attention. #Mahsa_Amini #مهسا_امینی

[Sarah Marzi @sj_marzi]

Back to school today to learn about the super neat single cell processing pipeline scFlow from @drcombiz @FancyNurun and @EugenePDuff 🤓😍

Check out the preprint here: https://t.co/sI56eA5vKM
R package: https://t.co/PCz4h8qeNs
nf-core pipeline: https://t.co/4ujKl9qkKg

[Dr Emma-Jane Mallas @e_mallas]

@British_Airways I’m already checked in for flight BA0995 from Berlin to LHR but have no seat allocated. Does this mean I am not guaranteed to fly? How can I get a seat allocation?

[Dr Emma-Jane Mallas @e_mallas]

@NeuroDocLucia demonstrates that real-world at home monitoring can provide a wealth of clinical information during recovery from traumatic brain injury #INTS2022

[Dr Emma-Jane Mallas @e_mallas]

@nialljbourke shows that we need to look beyond focal injuries to understand cognitive problems after traumatic brain injury #INTS2022

[Dr Emma-Jane Mallas @e_mallas]

@HazelGMay1 presents interesting preliminary data on potential biomarkers for blast induced brain injury at #INTS2022