Edoardo Sozzi

Postdoc @ETH_en @TreutleinLab | PhD @lunduniversity @ParmarLab | Human brain development, single cell sequencing, cell replacement therapy 🧠🧫🧬

[Edoardo Sozzi @edo_sozzi]

🎉 Happy to share that my main PhD project is now published in EMBO Journal!

How do human dopamine neurons connect with their striatal targets, and how does that influence their development and maturation?

Full story here: https://t.co/7FiMjL2XAk

#Neuroscience #DOPAMINE

[Edoardo Sozzi @edo_sozzi]

🔬 I’m happy to share our new preprint on bioRxiv, where we introduce connectoids — a human stem cell–based, compartmentalized model to reconstruct the nigrostriatal pathway in vitro.

📰 Read more here: https://t.co/kXUVC0nhHH

[Edoardo Sozzi @edo_sozzi]

Out now in Stem Cell Reports! ✨

In this work we present a 3D co-culture system for the generation of human somatostatin (SST) interneurons 🧠

📄 Read the full paper here:
https://t.co/NbQPMYmUeA

[Edoardo Sozzi @edo_sozzi]

Exciting news in Huntington’s disease research! Transplanted human striatal progenitors can functionally integrate and modulate host brain circuits in a Huntington’s disease animal model - a promising step toward cell based therapy!

Full story: https://t.co/9t3CycsGSn

[Edoardo Sozzi @edo_sozzi]

6 months ago I defended my PhD thesis, and looking back it feels both close and far away - so much has happened since then! Thanks to everyone who shared this journey with me, especially my supervisors Malin, Alessandro and Daniella, and also my opponent Gonçalo.

Onwards!

[Edoardo Sozzi @edo_sozzi]

Our review "Advances, challenges, and opportunities of human midbrain organoids for modelling the dopaminergic system" is out now on @embojournal 🧪🎉

With @Fiorenzano555 , @ParmarLab and the special contibution of @ArlottaLab 🧠

Read more here: https://t.co/M8nlXiBY80

[Alessandro Fiorenzano @Fiorenzano555]

Another piece added to the human mesencephalon puzzle: uncovering dopaminergic neuron identity based on their axonal target with transplantation, retrograde barcoding, and single-cell technologies 🧩🔬@ParmarLab @petter_storm @edo_sozzi @Bjorklund | PNAS https://t.co/lhAIUecM70

[Edoardo Sozzi @edo_sozzi]

Enjoyed presenting my work at #ISSCR2024 in the PSC-based cell therapy session co-chaired by Benedikt Berninger and @TabarViviane ! @ISSCR #ISSCR

[Edoardo Sozzi @edo_sozzi]

If you are at @ISSCR and want to discuss cell replacement therapy for Parkinson’a Disease, dopaminergic organoids or single cell RNA seq reach out! 🐭🧠Tomorrow Hall 3 at 1.30 🎙️
Today poster 181 at 3.45 with German Ramos Passarello 🧫

[Alessandro Fiorenzano @Fiorenzano555]

"Don't Miss Out! 🎉 Tomorrow, July 12: @edo_sozz Talk! Great science on Dopaminergic Neuron Transplants, cografts for Parkinson's, and lots of fun! 🧠✨ #ISSCR2024 @ParmarLab

[ISSCR @ISSCR]

Congratulations to the #ISSCR2024 Travel & Merit Award Winners! Thank you to all of our supporters.

[Brain @Brain1878]

Björklund & Barker summarize experimental data in support of the idea that transplants of cholinergic neurons could be used to restore cognitive function in patients with Parkinson´s disease. https://t.co/69vr7hr0hQ

[The Knoblich Lab @Knoblich_lab]

We are excited to share our latest work on developing a model of the human dopaminergic system with functional dopaminergic innervation, which we use to study Parkinson’s cell therapy as well as the reward system, published today in Nature Methods (https://t.co/2Xf6JyG3K2).

[Alessandro Fiorenzano @Fiorenzano555]

It was truly amazing to be a part of this @naturemethods Explore the innovative modeling of the Human Dopaminergic System using assembloid🧠🧠 Check out here for an insightful journey 👉https://t.co/E0bN86PZkj @Knoblich_lab @ParmarLab @CnrIgb @CNRsocial_ @Lund_Stem @MultiparkL

[Alessandro Fiorenzano @Fiorenzano555]

Multiple brain organoid culture in a fluidically interconnected 3D printed wells: all in one plat 🧠@Biofabrication @jankokaj @edo_sozzi @ParmarLab @CnrIgb @CNRsocial_

[Edoardo Sozzi @edo_sozzi]

Enjoyed presenting my work @ISSCR 2023! Thanks again to all the organizers for the beautiful meeting! @ParmarLab #ISSCR2023 #neuroscience #phdlife

[Medicinska fakulteten, Lunds universitet @medfak_LU]

On 13th of February, a transplant of stem cell-derived nerve cells was administered to a person with Parkinson’s at @skanesus, Sweden. The product has been developed by researcher @lunduniversity . #cambridgeuniversity #imperialcollegelondon #novonordisk #Parkinson

[Alessandro Fiorenzano @Fiorenzano555]

Check our latest paper "Human Fetal brain organoids"🧠🧠🧠🧠🧠🧠🧠😎 @ParmarLab @edo_sozzi @petter_storm @jankokaj @MarcellaBirtele
Out in @Dev_journal 👇 https://t.co/xMzG9LIFWr

[Lund University @lunduniversity]

Swedish Medical Products Agency grants approval for clinical study of new stem cell based Parkinson’s Disease treatment: https://t.co/mRChEFvhSM #parkinsons #parkinsonsdisease #medicine @Cambridge_Uni @ParmarLab @MichaelJFoxOrg

[Johan Jakobsson @JakobssonLab]

Dont miss our anniversary conference. Outstanding lineup. Registration is open now! @Lund_Stem

[Daniella Rylander Ottosson @Ottossonlab]

Cheers and congratulations Dr Jessica Giacomoni @ParmarLab @Ottossonlab for your well deserved PhD degree. Great defence with Faculty opponent Marisa Karow and committee members @CellReproLab @Iben_Lundgaard and Ulrika Englund.