For somebody working on the gut #microbiome, the responses ("gross", "embarrassment", "pseudoscience", etc.) to this @Nature article on the treatment of C-section babies with their mother’s poo are quite sobering. So, I thought I would provide a perspective in the thread below.
Our most complex biologic system—immunity—is reviewed in 3 new @CellCellPress papers, open-access
Adaptive
https://t.co/rJRBnV7u8I
Innate
https://t.co/PMKA6KgL7R
New insights
https://t.co/rJRBnV7u8I @RMedzhitov
This Cell paper on the 'cancer microbiome' repeats all the mistakes that gave us the so-called 'fetal microbiome'. Inadequate contamination controls, no culture data, no microscopy. And is it really ecologically plaucible that 165 genera colonize tumors?
https://t.co/Kiwl1rIWl1
Great occasion for my 1st tweet! Proud contributor to this @Nature perspective on the ongoing debate questioning a fetal #microbiome. With 46 experts in #microbiome#science and related disciplines, we assess the evidence. The answer, an unambiguous ‘No’ https://t.co/AK9JOyQGvs
Expert analysis refutes claims humans are colonised by bacteria before birth. @Pharmabiotic Prof @JensWalter15 and a global team of leading experts evaluated the evidence for microbes in human foetuses.
Published in @Nature today. - Read more at https://t.co/EYajei2qc9
Innate Immune Responses to Human Gut #Microbiota from Phylum to Strain: @MatthewSpindl13@jeremiahfaith1 examine how innate immune system responds to 277 human gut commensal #bacterial strains. Taxa induce signatures w/predictable immune phenotypes in mice https://t.co/FwQvtt09iL
One of my all-time favourites. Stare at the red dot on the woman's nose for 30 seconds, then look at an empty wall while blinking quickly. Promise it's worth it... https://t.co/jsmr9VtTjj
Gut bacteria linked to cognitive dysfunction. Age-related shifts in gut #microbiome increase isoamylamine (IAA) in humans. Same shifts in mice cause cognitive decline via S100A8. Blocking IAA binding to S100A8 promoter reverses memory/learning loss in mice https://t.co/k8aDQDNEhv
With all we've learned in recent years about the gut #microbiome, what is healthy eating now?
https://t.co/ashCdpiVzp A tour de force review @cellhostmicrobe
Rethinking healthy eating in light of gut microbiome: This review examines how diet-#microbiome-host interactions can validate, refine & innovate #dietary guidelines. Integration of microbiome science into #nutrition research will improve healthy eating https://t.co/XOYiskCSKF
Gut bacteria linked to cognitive dysfunction. Age-related shifts in gut #microbiome increase isoamylamine (IAA) in humans. Same shifts in mice cause cognitive decline via S100A8. Blocking IAA binding to S100A8 promoter reverses memory/learning loss in mice https://t.co/k8aDQDNEhv