Excellent overview by @JordiRemon on the latest developments in uncommon EGFR mutations... very interesting efficacy of 3rd generation EGFR TKIs! #EGFR#ESMOASIA25
Il male del nostro tempo sta tutto in questa domanda mostruosa: “definisci bambino”
dinanzi a chi denuncia il massacro di decine di migliaia di bimbi Palestinesi a Gaza.
E sta anche in chi permette di fare una tale domanda in TV, in nome del “contraddittorio”.
HARMONi: Ivonescimab+CT ⬆️ PFS vs CT in post-osi EGFRm NSCLC.Qx:
-How and when to place this strategy based new SoC 1st line?
-Control arm trial was CT not CT+Ami
-Data support Ivonescimab in EGFRm (table)
-What EGFRm obtain higher benefit of IVO? Predictive biomarkers
#WCLC2025
FLAURA2 trial: Osi + CT improves PFS & OS (⬇️ 23% risk death) vs Osi alone in mEGFR NSCLC. Qx:
-Intensification for all pts? Benefit in some subgroups only (Brain)
-Chemo or ami for intensification?toxicity QoL, relevant for decisions
-Cost
-Is Osi alone no more valid?
#WCLC2025
❗️BREAKING❗️Rescuers killed in line of duty.
Scenes like this unfold every moment in Gaza, often unseen, largely undocumented. I beg STATES: how much more must be witnessed before you act to stop this carnage?
🔴Break the blockade
🔴Impose an Arms Embargo
🔴Impose Sanctions.
@TobiasHuch@FranceskAlbs Disgusting. Children are starving to death in this genocide planned by Israel, and you’re thinking about how to explain to the people of Gaza that maybe they shouldn’t be marrying within their own families. There’s no need to worry—IDF is exterminating them all anyway
This is not business as usual.
My new UN report, From Economy of Occupation to Economy of Genocide, is out today.
It shows how corporations have fueled and legitimised the destruction of Palestine.
Genocide, it would seem, is profitable. This cannot continue, accountability must follow.
https://t.co/PV5wgeLpr2
#EconomyofOccupation #EconomyofGenocide
Israeli settlers, shielded by the #IDF, are deliberately destroying humanitarian aid meant for refugee camps.
An entire people raised from childhood to hate Palestinians.
#Genocide
Boicottare Israele si deve perché è l’unica cosa che noi possiamo fare per opporci al genocidio dei palestinesi.
E dobbiamo farlo perché i Governi continuano a finanziarlo e non mettono sanzioni a Israele nè bloccano i rapporti con quei criminali.
#BoycottIsraeliProducts
#lcsm: while small numbers from this phase 2 @JTOonline study, 5-year OS data seems to support 1L lorlatinib (76%!)
With this & updated CROWN data, is it time to universally prescribe 1L lorlatinib for all?
Triple targeted therapy is effective for pts with EGFR-mutant NSCLC with acquired BRAF alterations, mainly among pts with BRAF class I mutations @ESMO_Open@myESMO#BRAF#NSCLC
🔥Press Release: Ph III IMforte trial shows PFS+OS benefit for maintenance lurbinectadin + atezo post chemo-immunotherapy for ES SCLC
ADRIATIC, DELPHI, IMForte…finally, the SCLC landscape is changing
@OncoAlert #LCSM https://t.co/Na3HjXfg3t
Excited to share our new study @Nature. Very grateful for the support of our collaborators, pharma and biotech partners and members of the Skoulidis and Heymach labs. Special thanks to star fellow @_hanielaraujo and @minhtruongdo. Thankful to our patients. @MDAndersonNews
Biggest medical discoveries of the week (🧵)
1/10
A complete map of the fruit fly brain - the biggest and most detailed to date
140,000 neurons, which connect through 55 million synapses to permit vision, movement, and memory formation
(https://t.co/YTaJBwEhn2)