Our new paper showing synaptic gene expression changes in frontotemporal dementia due to the MAPT 10 + 16 mutation is out now in Neuropathology and Applied Neurobiology - well done team!! https://t.co/iogJwJoKOh
Huge congrats to @TSpiresJones (UK DRI at Edinburgh) who has been elected as a Fellow of the @acmedsci today!👏
Prof Spires-Jones is one of 58 exceptional scientists recognised for their remarkable contributions to advancing biomedical & health sciences👉https://t.co/5I4P4Xw9ve
Very glad to share these negative results beautifully presented by @ScotsFriction @ClaireDurrant1 and team. Fly neurons in our hands are very resistant to trans-synaptic spread of human tau! 🪰
https://t.co/QyTcBq2RbA
This May I’m running the Edinburgh Marathon fundraising for @alzscot. If you have the means to donate every pound makes a difference and would be greatly appreciated! Thank you! 🥰 https://t.co/MySgmtRZDt
Co-first paper from my work with @ClaireDurrant1 led with @Rob_McGeachan looking at physiological & pathological manipulation of Abeta in living human brain slices, and comparisons of patient characteristics and pathology w Abeta and tau.
@EdinUniNeuro
https://t.co/oPNS3OgoZW
Such cool data from the amazing @ClaireDurrant1 lab! Glad I was able to help a bit with this important work showing opposing roles of physiological and pathological amyloid-β on synapses in live human brain slice cultures
https://t.co/cZIZsNao2P
Check out our work studying the affects of amyloid-β on living human brain slice cultures! This work was very much a team effort, so big thanks to everyone involved! @DrSorayaM @ClaireDurrant1 @TSpiresJones @ScotsFriction @L_W_Taylor
https://t.co/euzxn3eIN1
Very excited to share our preprint investigating mechanisms of synapse loss and disease progression in progressive supranuclear palsy. This work wouldn't have been possible without the expert guidance of @TSpiresJones and @ClaireDurrant1
https://t.co/qZbym3gxYm
Check out our latest preprint from the brilliant @Rob_McGeachan co-led with my science buddy @ClaireDurrant1 Evidence for trans-synaptic spread of tau in PSP and live human brain slices! #TeamTau
https://t.co/BJocYsqBwl
Yay our latest paper is out! TMEM97 and abeta are close enough to generate a FRET signal in human synapses. Led by amazing Dr Marti Colom-Cadena and a great collaboration with colleagues @CogRx https://t.co/0J44IPSkwD
#ICYMI: A new study by @TSpiresJones (UK DRI at Edinburgh) has uncovered insight into how misfolded tau spreads through the #Alzheimers brain🧠
The research reveals clues as to how disease progression could be slowed👉https://t.co/LRHKWJYRVs
Very proud to share our latest paper out today showing oligomeric tau is a potential culprit in the spread of pathology through the brain in #Alzheimers - look at all of the lovely synapses! Strong work team! #tematau@NeuroCellPress https://t.co/5qUHLw9itg
Publication from our researcher Prof Tara Spires-Jones @TSpiresJones on how toxic proteins- Tau spread through the brain in dementia. The team discovered clumps of tau in the synapses of people who died of Alzheimer's disease https://t.co/RZjz38x3rL
#DementiaActionWeek#dementia
Strong work by our scientific editorial team member @elizabethsimzer writing this excellent editorial on the #Brain meeting for @braincomms https://t.co/tCHdQvMXiP