Ellen Horste

golden doodle PhD

[Ellen Horste @EllenHorste]

@xiuzhenchen @ule_lab @Mayr_Christine @MervinFansler Congratulations Xiuzhen! Very elegant and so cool :)

[Christine Mayr @Mayr_Christine]

Our new paper!
mRNAs play structural roles in the cytoplasm.
The longest mRNAs bound to FXR1 generate an mRNA-protein assembly that plays an essential role in cellular signaling by enabling proximity of proteins without RNA binding domains.
https://t.co/UtNTjM0LGX

[Ellen Horste @EllenHorste]

@MervinFansler Fantastic Merv! Congrats

[Ellen Horste @EllenHorste]

@MervinFansler @xiuzhenchen

[Ellen Horste @EllenHorste]

Just as the trajectory of a person’s life is heavily influenced by the neighborhood they grow up in, we found that the protein output of an mRNA is highly influenced by its location of translation. Ho ho ho🎅🏼 ⁦⁦@Mayr_Christine⁩ ⁦ https://t.co/QImKhHk5v3

[Ellen Horste @EllenHorste]

@paolocifani 😂

[Christine Mayr @Mayr_Christine]

New preprint! We (@xiuzhenchen) found a new mRNP network that covers the whole cytoplasm. We call it the FXR1 network, as it is formed through packaging of exceptionally long mRNAs by FXR1.

[Ellen Horste @EllenHorste]

@Mayr_Christine @xiuzhenchen Congratulations @xiuzhenchen !! Printing now🤓

[Ellen Horste @EllenHorste]

@shelbynewsad ����‍💨

[Ellen Horste @EllenHorste]

@shelbynewsad @CompoundVC Congrats Shelby!

[Ellen Horste @EllenHorste]

@ezgi_hsuleyman @UFScripps @darnelr Congratulations Ezgi!

[Ellen Horste @EllenHorste]

@MildredUnti Congrats Millie!

[Ellen Horste @EllenHorste]

Register below if you love startups and snacks 😏

[OncoPrecision @OncoPrecision1]

Our CSO and CEO will be participating in a panel discussion alongside Dr. Stacy Blain, Co-Founder & CSO and Acting CEO of Concarlo Therapeutics, and Dr. Rayees Rahman, Co-Founder & CEO of Harmonic Discovery next Tuesday.

Register here: https://t.co/2NJDhl0Czu

[Ellen Horste @EllenHorste]

Come thru! Tri-I RNA is here to stay!

[Tri-I RNA Club @Tri_I_RNA]

We had a great symposium with fantastic speakers, awesome audience, fun trivia, and food and drinks afterwards!! We thank our sponsors @ACDbio @AzentaSciences @TwistBioscience for making it possible! 👏👏

[Ellen Horste @EllenHorste]

@WeiruiMa Finishing revisions now- fingers crossed😅🤞🏻

[Ellen Horste @EllenHorste]

@WeiruiMa Beautiful! In a whole organism🤯

[Ellen Horste @EllenHorste]

🚨pre-print alert🚨mRNAs bind IDRs to control protein activity, effectively acting as post-translational modifications🤯🧬. Congrats @VickyLuo0223 !

[Christine Mayr @Mayr_Christine]

New preprint from us!

mRNAs act as chaperones for IDRs.

mRNAs often bind to IDRs. This changes their conformational ensembles to drive protein complex assembly, and controls protein activity.

Thank you @VickyLuo0223!

https://t.co/0LeTA2bjXv

[Ellen Horste @EllenHorste]

@DrSynbio ��

[Ellen Horste @EllenHorste]

@BeccaWeisz @RuPaulsDragRace 💖💖💖

[Ellen Horste @EllenHorste]

@WeiruiMa Thanks Weirui!!

[Ellen Horste @EllenHorste]

A lot of people (my parents) have been asking what I’ve been up to for the past 5 yrs…just working out how mRNAs stay organized!
Check it out🧬🤓:
https://t.co/dn8rDxB1Oy