Eric Aird

Postdoctoral Researcher in the Corn lab at ETH Zurich. CRISPRing by weekday, skiing by weekend.

[Jacob Corn @jcornlab]

Proper organelle regulation during mitosis is a must, but how do membrane-less condensates like PML bodies behave during cell division? In work led by @eric_aird, we found the balance of speckled proteins SP110 & SP100 to be the key. https://t.co/MkNBfYPxcJ

[Jacob Corn @jcornlab]

Many genome-editing tools work by cutting DNA - but the shape of the cut matters. Using #CRISPR screening, we show ERCC6L2 is specifically required to maintain #DNArepair fidelity at staggered DNA breaks, but not at blunt ends.
https://t.co/MbW8DTjIre

[Jacob Corn @jcornlab]

Amazing postdoc Eric Aird asked how #CRISPR gRNAs & interferon regulate innate #immunity. He found a wild partnership that balances appropriate response w/ cell death. SP100 builds filaments that kill cells, and SP110 breaks them to keep things in line. https://t.co/xJ4Xi3W8m8 🧵

[Joana Ferreira da Silva @FerreiraSilvaJ]

Today in @bioRxiv, we describe Click Editors (CEs) which combine DNA-dependent DNA polymerases, HUH endonucleases and RNA-programmable nickases for versatile genome editing without double-strand breaks 🧬. A study co-led with @connorjtou. A 🧵 (1/14):
https://t.co/lSO6Kk0Rk9

[Kevin Holden @KevinHoldenSF]

WORLD CRISPR DAY is back!
We'd love for you to join us at @Synthego's amazing, virtual, free scientific symposium that brings together genome engineering scientists, clinicians, and thought leaders from around the world!

Please register for free at https://t.co/vq2yHM0oMt

[D-BIOL @ ETH Zurich @ETH_DBIOL]

The @jcornlab reports on Recursive Editing, a way to drive high levels of #CRISPR-mediated precise genomic modification without manipulating cell factors or state. An accompanying easy-to-use software designs experiments to optimize target selection. https://t.co/eLf7CorruW

[ETH-Zukunftsblog @ETHZukunftsblog]

The latest #CRISPR-​based genome editing systems are safer for patients who will soon benefit from gene therapies, as @eric_aird explains in the latest #ZukunftsBlog @ETH_en @ETH_DBIOL #GenomeEditing
https://t.co/f1qvFBR8AR