💬 "I’m glad my data will play a role in bringing hope to more cancer patients" 💬
Precision oncology has given Dan Murphy new hope.
Now, he's sharing his story – and his data – to bring that hope to other patients.
🍁 Full story ▶ https://t.co/82yelY1rTw
PASS-01 trial #PDAC#ASCO24
➡️rand ph2 mFFX vs.GnP
➡️WGS/RNA/PDO/CTCs/ctDNA
✅PP PFS 5.5 (GnP) vs. 4.0mths (mFFX)
➡️PP ❌gBRCA/PALB2 >KRASWT in GnP
➡️MTB directed 2nd line
➡️ GnP remains a backbone for drug dvp
➡️basal-like unmet need
Proud @AmberHabowski as translational leads
A special evening today: Dr. Pamela Munster gets endowed with Mariam Moghadam Safinia distinguished professorship in hereditary cancer research
@UCSFCancer#breastcancer#Oncology#researchers
🍁 MAESTRO: A Pan-Canadian project to accelerate #precisionmedicine for #pancreaticcancer🍁
🩺 Sadly, #PancreaticCancer is one of the deadliest cancers
🩺 Today, patients have very few treatment options, and those that exist are often ineffective
@pmcancercentre looking forward to Cancer Genomics - Tumor Immunotherapy Program Annual Symposium on Friday Nov 10 in MaRS auditorium. Amazing line up of speakers 👏🔥 https://t.co/kSaT2O8kr6
RMC-6236 RAS-MULTI (ON) inhibitor
➡️promising activity in heavily pre-treated PDAC pts
➡️ORR 20% in 46 pts
➡️median time to response 1.4mths
➡️median time on tx 3.3 mths
✅ctDNA clearance >50% in 92%
➡️likely to need combinations but +exciting for PDAC #ESMO23#PancreaticCancer
PREOPANC-2
➡️FFX vs Gemrads in resectable/
early BR #PancreaticCancer
➡️no diff in resection rates/OS/toxicity
❓recurrence patterns
➡️Nb full dose FFX
#ESMO23
"Deciphering the Pathways to PARP Sensitivity in Pancreatic Cancer" commentary by Dr @EricaTsangMD and Dr Gallinger on our (@KReissMD) recent paper in @CCR_AACR
https://t.co/cUv4J1GDXl
Always a treat to hear @Aiims1742 describe RAS signalling and differences in KRAS mutant alleles in #PancreaticCancer pathogenesis
➡️ integration of transcriptomics to interrogate TME and metabolomics #abstract4020
✅ Differences certainly in G12D vs G12R
A great opportunity to support the next generation of cancer research @AACR the Undergraduate Student Poster Competition is open until 4PM #AACR23#AACRGlobalScholars
I had the best of times hearing about the research projects presented in the undergraduate student caucus and poster competition. So much enthusiasm and talent packed in a room! Thank you to the #AACRAMC judges @KristinAltwegg @waynerlawrence @MathiasSeviiri@safamajeed
Happy International Women’s Day! Come join us Women-in-Cancer for our new series “Strengthening through Perspectives” and engage with our growing international community! Register at https://t.co/RFN9lah8v9 @DrCESimmons@DrCBrezden@HinaSaeedMD@IshwariaMD@belinda_campbe
Just published! A phase Ib trial of the PI3K inhibitor alpelisib and weekly cisplatin in patients with solid tumor malignancies. Read more in this study by @EricaTsangMD et al.
https://t.co/WYCtvMfSYp
@UCSF#openaccess