Edwin Ross

[GU Pathology Society (GUPS) @GU_Path_Society]

Happening next Thursday, Nov 5 at 12 PM Eastern time.

Register now: https://t.co/7424UCBYiX

[Isidro Machado MDPhD @MachadoIsidrin]

See you in the upcoming N.O.D.E session, thanks

[Craig Horbinski @CraigHorbinski]

One look at this intraoperative smear prep and you can diagnose this brain tumor. #pathology #neuropath #pathtwitter

[RC of Pathologists @RCPath]

Discover Dermatopathology on the #PathologyPortal! Learn through real cases, digital whole slide images, and expert-led videos by Dr Jerad Gardner, designed for all levels. Topics include tumours, inflammatory conditions, and congenital disorders. Visit:
https://t.co/xtCP7dY4vi

[Cirugía Pediátrica Javeriana @cirupedjavecali]

Club de Residentes Iberoamericanos de Cirugía Pediátrica 🌎
Martes 13 de octubre

Invita:
Pontificia Universidad Javeriana, Cali, Colombia
Asociación Iberoamericana de Cirugía Pediátrica

Link: https://t.co/jfjFqYsNT8

[Dr. Arkadip MD @pathognosis22]

Probably the most important table so far. #MMR #PDL1 #HER2 #IHC #FISH #pathognosis #pathtwitter

[rajEndiran @rdpatho]

🔬 Not Clear Cell RCC… So What Is This? 😱 (63F, HBV+, Cirrhosis)

[International Society of Gynecologic Pathologists @ISGynP]

Announcing a free @ISGynP sponsored live virtual slide session on Oct 8 @ 12 noon US ET by Dr. Kabbach - "A Practical Approach to Vulovovaginal Non-Squamous Tumors". Register now @ https://t.co/Q2UBdsCCsy
#gynpath #gynaepath #PathTwitter

[GU Pathology Society (GUPS) @GU_Path_Society]

Join us for our next Distinguished Lecture Series session featuring Dr. Jesse K. McKenney

Topic: Spindle Cell Lesions of the Genitourinary Tract

Moderators:Dr. Emily Chan @chemily7, Dr. Rohit Mehra @drmehrarohit

Nov 5, 12 PM Eastern time

Register here: https://t.co/uPaNYi7XxD

[Brain Pathology @brainpathol]

Gliomas with pleomorphic and pseudopapillary features (GPAP) are circumscribed tumors with targetable mutations, prolonged survival, and frequent tumor predisposition
https://t.co/7CXOiZspzg

[Pathological Society @pathsoc]

2 WEEKS TO GO UNTIL OUR NEXT PATHOLOGY GRAND ROUND LECTURE!!

Dr Sarah Aitken, recipient of the Wyllie Lecture and Medal 2026, on "Genomic Pathology: from DNA mutations to cancer evolution" 🔬

📅14 October 2026, 13:00 - 14:00 (UK time)

🔗Register: https://t.co/9e8oYyUmrr

[GU Pathology Society (GUPS) @GU_Path_Society]

Join us on Thursday, Oct. 1 for our next Virtual Education Series: Bridges in Genitourinary Oncology- From Pathology Phenotypes to Clinical Realities.

Speakers: @TingZhaoPathdoc, @DrSwatiBhardwaj, Dr. Gabriela Quiroga-Garza.

🕛 12–1:30 PM EST

Register: https://t.co/tLl1bGJri3

[Janira Navarro @Janiranavarro]

Crowded Gleason pattern 3

Glands are back-to-back and can look cribriform
Pitfall: calling it pattern 4
A keratin stain will highlight the architecture and show they are individual glands

Dr. McKenney. Prostatic Adenocarcinoma Grading: 2026 Update #USCAP #pathology #PathX

[Janira Navarro @Janiranavarro]

Gleason pattern 4- Anastomosing cords pattern

Represents the other 5-7% of prostate carcinomas associated with highly aggressive disease

Dr. McKenney. Prostatic Adenocarcinoma Grading: 2026 Update #USCAP #pathology #PathX

[Janira Navarro @Janiranavarro]

Gleason Pattern 4: Poorly formed glands

None of these glands have lumina, this is not tangential section .
Probably you could think this is grade 5. Do not call it grade 5
Across all clinical outcome groups, this morphologic pattern is NOT associated with metastatic potential.

Dr. McKenney Prostatic Adenocarcinoma Grading: 2026 Update #USCAP #pathX #pathology

[Dr.hou @DrHou_pathology]

Diagnostic Approach to Sinonasal Small Round Blue Cell Tumors

For the initial immunohistochemical evaluation of sinonasal small round blue cell tumors, a screening panel including AE1/AE3, p40, synaptophysin (Syn), SOX10, CD45, CD99, and desmin may be employed to assess epithelial, neuroendocrine, neural crest/melanocytic, hematolymphoid, and myogenic differentiation.

[C.Alberto Ortega @albertoortegana]

What is your diagnosis for this 45-year-old patient with erythematous-violaceous papules and annular plaques, with biopsy showing neutrophil-rich palisading granulomas surrounding necrobiotic collagen?
Dr. Harinder Sandhu

[C.Alberto Ortega @albertoortegana]

What is your diagnosis for this patient with multiple erythematous-violaceous nodules and plaques, with histology showing a dense dermal follicle-centered B-cell infiltrate?
Dr. Harinder Sandhu

[Janira Navarro @Janiranavarro]

Prostate - Gleason pattern 3

Well-formed individual glands; some may have a small lumen (pic 1, yellow arrow)

Occasional glands without a lumen and focal branching are acceptable

Evaluate at low power

Dr. McKenney. Prostatic Adenocarcinoma Grading: 2026 Update #USCAP #pathology #pathX

[Dr.hou @DrHou_pathology]

Diagnostic Approach to Large B-Cell Lymphoma

Large B-cell lymphoma (LBCL) is the most common type of aggressive mature B-cell lymphoma. In the 5th edition of the WHO Classification of Haematolymphoid Tumors, LBCL has been further refined into as many as 17 distinct specific subtypes. Cases that do not fit into any defined subtype are classified as diffuse large B-cell lymphoma, not otherwise specified (DLBCL, NOS). The increasing precision of LBCL classification requires pathologists to adopt more accurate and comprehensive diagnostic strategies. Meanwhile, the continuous development of novel therapeutic agents and the diversification of treatment approaches have placed higher demands on precise LBCL subclassification and the identification of clinically relevant molecular alterations.

The diagnostic workup typically includes an immunohistochemical panel consisting of CD20, PAX5, CD3, CD5, CD10, BCL2, BCL6, MUM1, CD138, Cyclin D1, CD30, p53, MYC, Ki-67, and Epstein–Barr virus (EBV)-encoded RNA (EBER) in situ hybridization. In addition, fluorescence in situ hybridization (FISH) analysis is performed to detect genetic rearrangements involving MYC, BCL2, BCL6, and IRF4, among other relevant molecular abnormalities.