Essentials by Nature

Wholistic minded retired health professional interested in all things organic

[Sama Hoole @SamaHoole]

There is now a serious, well-funded plan to vaccinate every cow on earth, twice a year, so it burps less politely. Bill Gates is behind it. So is the New Zealand government. Somewhere a marketing department is very proud.

The company furthest along calls its methane vaccine the holy grail of livestock emissions, a phrase that should make you reach for your wallet and check it is still there.

The pitch is gloriously simple. Train the cow's own immune system to turn on the microbes in her gut, so she belches less methane, with a single jab lasting months. Early results suggest a cut of ten to fifteen per cent. Trials run through 2027, launch around 2030, by which point the dream is a needle in the neck of every cow they can corner.

Pause on that. Not a feed tweak. A plan to medicate an entire species, forever, across the whole planet, to fix a problem with how we count its burps.

Because methane from a steady herd cycles out of the air within about a decade. It does not pile up like fossil carbon. A stable national herd adds no new warming whatsoever, whatever the headlines shriek. The cow was convicted by an accounting method, and the sentence is a lifetime of injections.

And follow the money, because it does the confessing for you. The cash floods in from billionaire climate funds and the food giants chasing their own supply-chain targets, the very people who need the cow to look guilty so their spreadsheets come out green. Not a penny from the farmer, who just inherits the syringe and the bill.

So the grass-fed cow, quietly turning rain and sunshine into food on land that grows nothing else, is now a wellness patient with a biannual appointment. Marvellous. The cow was never the emergency. The people insisting she is just happen to have a vaccine to sell.

[𝕐o̴g̴ @Yoda4ever]

Weighing foster kittens..they understood the assignment..🐈🐾😍

📹julidixonmath

[Lucy @TheLucyShow1]

Watching this will remind you just how beautiful life can be 💫💕🎶

[John Cleese @JohnCleese]

This means a cultural wipe-out for a complete commuity

Madness

[Give A Shit About Nature @giveashitnature]

Flaco the Eurasian Owl escaped Central Park Zoo in February 2023 when an unknown person cut the stainless steel mesh of his enclosure. For a year, he survived among the Manhattan skyscrapers. In February 2024, he was found dead on a sidewalk.

The necropsy found four different rat poisons in his body.

We know Flaco's story because he had a name and a reputation, but unfortunately, this story plays out among hundreds, if not thousands of birds of prey every year.

A 2020 Tufts study found anticoagulant rodenticide in 100 percent of 43 red-tailed hawks tested across the northeastern US. In California, 92 percent of tested predatory birds showed exposure. In Massachusetts, 86 percent of dead raptors tested positive. In 2024, an entire great horned owl family in Lincoln Park died of rodenticide poisoning.

The mechanism is the same every time. A poisoned rat doesn't die right away. It takes up to ten days, stumbling around in the open, slow and easy to catch. The owl eats it. Then another. Then another. The poison accumulates up the food chain until it kills the animal that was doing your rodent control for free.

A barn owl family eats between 1,000 and 3,000 rodents a year at no cost to you. The rodenticide under your sink does the same job and kills the barn owl too.

Flaco survived a zoo escape, a Manhattan winter, and a year of hunting in one of the densest cities on Earth. The thing that killed him was the poison on the shelf of your local hardware store.

[Dr. Jennifer Irwin @drjenirwin]

Long-term neurological & cognitive impact of COVID-19: systematic review & meta-analysis in over 4 million patients

Findings included:
fatigue 43.3%
memory disorders 27.8%
cognitive impairment 27.1%
sleep disorders 24.4%
concentration impairment 23.8% https://t.co/Mldydwj5M3

[Dana Parish @danaparish]

🚨 More big accounts spreading dangerous misinformation. Have to wonder if they are being paid to do so. This one-dose doxy rec is verifiably false!!! Here’s top expert MD calling it “malpractice” & EXPLAINING THE SCIENCE!! One-dose DOESN’T PREVENT LYME!!

[Afshine Emrani MD FACC @afshineemrani]

I'm a cardiologist. For months I've been telling you that inflammation is the fire behind heart disease — not just cholesterol. That we've been treating the smoke while the fire kept burning.

Penn Medicine just built the fire extinguisher.

They took the most powerful immune technology in cancer medicine — CAR T-cell therapy — and flipped it. Instead of engineering killer cells to destroy tumors, they engineered regulatory T cells to suppress the chronic arterial inflammation that causes heart attacks.
Published in Circulation. The results stopped me cold.
In CAR T cancer therapy, doctors extract your T cells, genetically engineer them to recognize a specific target, and infuse them back into your body as precision-guided missiles. It has cured previously terminal blood cancers. The technology won its developers a Nobel Prize.

The Penn team asked a question no one had asked before: what if we aimed this at the arteries?
They engineered regulatory T cells — Tregs, the immune cells whose job is to calm inflammation rather than cause it — to specifically target oxidized LDL. OxLDL is the molecule that starts the entire atherosclerotic cascade. It infiltrates your artery wall, triggers macrophages to gorge on it and become foam cells, releases inflammatory cytokines, recruits more immune cells, and builds the plaque that eventually ruptures and causes a heart attack.

OxLDL is the match that lights the fire. These engineered CAR Tregs are designed to find that match and snuff it out — at the arterial wall itself.

The results in mouse models of atherosclerosis:
Blocked macrophage foam cell formation — the cellular process that builds plaque. Dramatically reduced arterial wall inflammation. Prevented over 70% of plaque buildup compared to untreated controls. And critically — preserved normal immune function everywhere else.

That last point is essential. Previous anti-inflammatory approaches to atherosclerosis failed because they suppressed the entire immune system — leaving patients vulnerable to infections and other complications. Colchicine works modestly. Canakinumab in the CANTOS trial reduced events but increased fatal infections. The immune system is a sledgehammer. You can't just turn it down globally.
CAR Tregs solve this by being targeted. They don't suppress your whole immune system. They patrol your arteries specifically, calming the inflammation at the exact site where it's causing damage — and leaving the rest of your immunity intact.

One infusion. Targeted. Precise. The cells do the work.
Lead author Robert Schwab of Penn Medicine put it directly: "If we can get the immune system to see OxLDL and provoke an anti-inflammatory response, it would reduce inflammation and essentially stop the pathogenesis in its tracks."

Senior author Avery Posey: "Our study shows for the first time how CAR T cell technology could be used to treat the underlying cause of the most common form of heart disease — the leading cause of death worldwide."
As a cardiologist who has spent twenty years treating the downstream consequences of arterial inflammation — the stents, the bypasses, the cardiac rehab, the second heart attacks — I need you to understand what this represents.

Every treatment I currently have manages the damage after the fire has burned. Statins lower the fuel supply. Blood pressure meds reduce the mechanical stress. Stents prop open arteries that have already narrowed. These save lives. I use them daily.
But none of them put out the fire itself.
CAR Tregs are engineered to extinguish the inflammation at its source — inside the artery wall — before the plaque builds, before the vessel narrows, before the rupture, before the heart attack.
This is the shift from managing disease to correcting the biological process that causes it. At the cellular level. With living medicine.

This was demonstrated in mice, not humans. The leap from mouse models to human cardiovascular trials is enormous and filled with failures. Manufacturing CAR T cells is currently expensive — roughly $400,000 per treatment in cancer. Scaling this for a disease that affects billions would require a manufacturing revolution. Long-term safety of engineered immune cells patrolling human arteries for years or decades is completely unknown. Human trials are likely years away.
But 70% plaque reduction. With preserved immune function. Targeting the exact inflammatory mechanism I've been writing about for months. Published in Circulation — the flagship journal of the American Heart Association.
The trajectory is unmistakable.
Gene editing to permanently lower cholesterol. Personalized mRNA vaccines to hunt cancer. GLP-1 drugs rewiring metabolism. Cellular reprogramming to reverse aging. And now — living immune cells engineered to extinguish the inflammation that causes the number one killer on earth.
Every one of these treats the root cause instead of managing the downstream damage. Every one of them was impossible a decade ago. Every one of them is in trials or approaching trials right now.
I've held dying hearts in my hands in the cath lab at 3 AM. Hearts that were destroyed by inflammation I could see but couldn't stop.
The day I can infuse a patient with cells engineered to stop that inflammation before it ever builds the plaque — that's the day cardiology changes forever.
We're not there yet. But the fire extinguisher just passed its first test.

[Eric Verhaeghe @Verhaeghe]

Bruxelles vous interdit d'échanger vos graines (et même un greffon) avec votre voisin
À partir du 30 juin 2026, les micro et petites exploitations agricoles entrent à leur tour dans le champ du règlement européen contre la déforestation (EUDR). En parallèle, les nouvelles règles européennes sur le matériel de reproduction des végétaux encadrent drastiquement les échanges de semences et interdisent ceux de greffons d'arbres fruitiers entre particuliers. Une accumulation de normes qui nourrit le sentiment d'un fossé grandissant entre Bruxelles et le monde paysan.
#UE #agriculture

https://t.co/vIG9UBDQkJ

[C.L.A.U.D.I.A @DaAcervo]

A fumaça de alecrim no galinheiro é um método antigo que ainda funciona.

🌿 Antes dos desinfetantes industriais, os camponeses italianos e os seus homólogos franceses, queimavam molhos de alecrim seco no estábulo e no galinheiro uma vez por mês.
Não era um ritual. Era uma técnica.

O alecrim queimado liberta em fase gasosa cânfora, cineol, alfa-pineno e ácido rosmarínico.
Em espaço fechado, estes compostos atingem concentrações letais para os artrópodes: moscas, mosquitos, ácaros, pulgas e piolhos, sem afetar mamíferos e aves, que toleram concentrações muito superiores.
É esta seletividade que tornava a técnica viável num galinheiro cheio.

— O ácaro vermelho (Dermanyssus gallinae) é o parasita mais temido na avicultura.
Esconde-se nas fendas da madeira dos poleiros durante o dia e suga o sangue das galinhas à noite.
Uma infestação forte provoca anemia, queda na postura e mortalidade dos pintos.
Os camponeses fumigavam o galinheiro vazio (galinhas fora), deixando a fumaça penetrar em cada fenda durante uma hora. O efeito durava 2 a 3 semanas.

As moscas dos estábulos; Stomoxys calcitrans e Musca domestica, caíam em poucos minutos.
A fumigação mensal interrompia progressivamente o ciclo reprodutivo.

A tradição não se limitava ao alecrim:

• Sálvia seca: mesmos princípios ativos, usada onde faltava alecrim.

• Zimbro seco: fumaça resinosa eficaz contra moscas e mosquitos, clássica nos estábulos alpinos.

• Lavanda seca: fumigação dos quartos contra percevejos; o linalol queimado tornava as fendas da madeira inabitáveis.

🌿 A fumigação com ervas também tinha um papel de desodorização.
A fumaça aromática mascarava o amoníaco do estrume; um irritante respiratório real para bovinos, suínos e aves.
Reduzir essa concentração melhorava concretamente o bem-estar dos animais.

🌿 Hoje, para quem gere um pequeno galinheiro biológico onde os tratamentos químicos não são desejáveis, queimar um molho de alecrim seco no galinheiro vazio uma vez por mês continua a ser um tratamento complementar contra o ácaro vermelho: sem resíduos, sem contaminação dos ovos e com o custo de um ramo.

[Harshi Peiris, Ph.D. @Neuroscope_mp]

BREAKING 🧵

A gut bacterium is showing up — or rather disappearing — across all three phases of COVID-19.

Severely ill patients have less of it.
Recovered patients get it back.
Long COVID patients don't.

Its name is Faecalibacterium prausnitzii. And what it does explains a lot. 👇

[Liam's LC/ME Journey @liamsLCjourney]

@Wunderlust_100 I've found @SalvMattera's https://t.co/ifIwDVqVcU to be a great doctor listing for the USA!

Best to check the "providers with reviews only button" to cut down on the auto-imports.

[Liam's LC/ME Journey @liamsLCjourney]

Until now, there has not been a list of recommended UK Long COVID and ME doctors all in one place... so we decided to make one!

https://t.co/NnYarA6rEq 🇬🇧

We painstakingly collated hundreds of comments from Reddit, Twitter, and group chats with only the most-rated doctors, pricing, and pros and cons from real patients.

25 doctors and clinics are listed, from NHS to private specialists, pharmacies for LDN and ketotifen, and even a link-out to @ChronicLiving1 for therapy options!

This is a living document and will be continually updated. Suggestions and updates welcome!

[Dr LG @subversivepsych]

University of oxford are doing a study #MECFS #LongCovid #pwME #pwLC

[Vance 🌞⚡️ @VanceE]

My bad, let me speak plainly.

If you have depression or anxiety and are spending thousands on talk therapy and not $50 on probiotics, you might not make it.

But it’s bad depression?

“L. rhamnosus may have a more pronounced effect on individuals with more severe depressive symptoms”

How long?

“Moludi et al. found a 12-week L. rhamnosus supplement significantly reduced moderate to severe depression cases from six to zero”

I am blown the fk away again.

[Dr. Zakaria MD @ZakariaMDv3]

Many patients have inquired about the need to use Ivermectin, Fenbendazole, and Mebendazole simultaneously. This will clarify the situation for you. Each of these substances operates through distinct mechanisms and targets cancer in unique ways.

Ivermectin vs. Fenbendazole vs. Mebendazole
🔬 Ivermectin vs. Fenbendazole vs. Mebendazole: 12 Powerful Anti-Cancer Mechanisms Each Uses to Attack Tumors
These repurposed medications were originally designed to fight parasites — but research and real-world use have shown they do much more. Each one attacks cancer on multiple biological fronts, helping shut down tumor growth, starve cancer cells, boost the immune system, and more.
Here’s a breakdown of how each works:
✅ IVERMECTIN – 12 Known Anti-Cancer Actions
1. Inhibits WNT/β-catenin pathway – stops cancer cell proliferation
2. Induces apoptosis – triggers programmed cancer cell death
3. Blocks importin α/β transport proteins – prevents cancer cell replication
4. Inhibits PAK1 enzyme – reduces inflammation and tumor progression
5. Anti-angiogenic – stops formation of new blood vessels in tumors
6. Immune system modulator – enhances recognition of cancer cells
7. Autophagy disruptor – interferes with cancer cell survival strategies
8. Targets glioblastoma stem cells – effective in brain cancers
9. Inhibits mitochondrial respiration – cuts off energy supply to tumors
10. Disrupts mTOR signaling – slows cell growth
11. Overcomes chemotherapy resistance – makes chemo more effective
12. Antiviral properties – potentially helpful for virus-related cancers (like HPV)
✅ FENBENDAZOLE – 12 Known Anti-Cancer Actions
1. Microtubule disruption – prevents cancer cells from dividing
2. Inhibits glucose uptake – starves cancer cells of energy
3. Activates p53 tumor suppressor gene – helps kill damaged cells
4. Triggers apoptosis (cell death) – particularly in lung, colon, and prostate cancer
5. Inhibits metastasis – prevents cancer from spreading
6. Enhances oxidative stress in cancer cells – makes them more vulnerable
7. Immune modulator – may help immune system target tumors
8. Blocks angiogenesis – stops tumors from building blood supply
9. Depletes glutathione in tumors – weakens their defense
10. Suppresses AKT signaling pathway – involved in cell survival
11. Restores normal cell cycle regulation – prevents uncontrolled growth
12. Synergistic with other natural agents (e.g., CBD, curcumin, vitamin D)
✅ MEBENDAZOLE – 12 Known Anti-Cancer Action
1. Microtubule destabilization – similar to fenbendazole
2. Inhibits angiogenesis blocks new blood vessel growth
3. Triggers apoptosis – causes cancer cell death
4. Inhibits VEGF signaling – blocks tumor blood supply signals
5. Crosses blood-brain barrier – useful for brain cancers
6. Activates caspase-3/7 enzymes – involved in programmed cell death
7. Reduces MYC oncogene expression – slows tumor growth
8. Inhibits Bcl-2 protein – lowers cancer cell survival
9. Anti-metastatic – reduces spread of cancer
10. Disrupts mitochondrial function – energy production in tumor cells fails
11. Improves chemo sensitivity – helps standard treatments work better
12. Low toxicity + long safety record – used in humans for decades
🌱 Each of these medications targets cancer through different biological pathways.
#Ivermectin
#Fenbendazole
#Mebendazole
#Cancercure.

[Denis - The COVID info guy - @BigBadDenis]

A new study finds the dementia drug Donepezil helps treat Long COVID fatigue and depression. The virus triggers a protein that drops brain acetylcholine; Donepezil restores it to clear brain inflammation and symptoms.

https://t.co/RKaTjOq2f0

[Afshine Emrani MD FACC @afshineemrani]

I'm a cardiologist. After 40, stop guessing about your health. These numbers tell you whether you're building a long, vibrant life — or quietly declining without knowing it.

I run these on myself. I run them on every patient I care about. Most are cheap bloodwork. All are available now. And together, they paint a picture no standard annual physical will ever give you. Print this. Bring it to your next appointment. Your 60-year-old self will thank you.
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𝗙𝗮𝘀𝘁𝗶𝗻𝗴 𝗜𝗻𝘀𝘂𝗹𝗶𝗻
Target: below 5 μIU/mL. Ideal: 3-4.
This is the 10-year warning bell your standard panel completely misses. Your glucose and A1c can look "normal" for a decade while your pancreas is working overtime to keep them there. Fasting insulin catches insulin resistance 5-10 years before your A1c moves. By the time A1c rises, the damage is already extensive.

𝗛𝗢𝗠𝗔-𝗜𝗥
Target: below 1.0.
Calculated from fasting insulin and fasting glucose. The single best measure of insulin sensitivity. Above 1.0 and your metabolism is already under strain. Above 2.5 and you're insulin resistant — even if every other number looks fine.

𝗛𝗯𝗔𝟭𝗰
Target: below 5.4%.
Not below 5.7% — that's the threshold where medicine calls you "prediabetic." By then you've been metabolically compromised for years. Optimal is below 5.4%. Blood sugar mastery is longevity mastery.

𝗧𝗿𝗶𝗴𝗹𝘆𝗰𝗲𝗿𝗶𝗱𝗲 : 𝗛𝗗𝗟 𝗥𝗮𝘁𝗶𝗼
Target: below 2. Ideal: below 1.
Your metabolic health crystal ball. This ratio predicts insulin resistance, cardiovascular risk, and metabolic syndrome better than any single lipid number alone. A ratio above 3.5 is a red flag regardless of what your total cholesterol says.

𝗔𝗽𝗼𝗕
Target: below 80 mg/dL for moderate risk. Below 60 for high risk.
I've written about this extensively. ApoB counts every atherogenic particle hitting your artery walls. A 2024 analysis found 54% of patients had dangerous levels that standard LDL testing completely missed. If you only know your LDL, you're driving with one eye closed.

𝗟𝗽(𝗮)
Test once in your lifetime.
100% genetic. 1 in 5 Americans are elevated. Triples heart attack risk independently of everything else on this list. Diet and exercise cannot lower it. The 2026 ACC/AHA guidelines now recommend everyone be tested. Most never have been.

𝗵𝘀-𝗖𝗥𝗣
Target: below 1.0 mg/L.
You can have perfect cholesterol and inflamed arteries silently preparing to rupture. hs-CRP measures the fire behind the plaque. The JUPITER trial proved that finding and treating inflammation saves lives — even when lipids look fine. If this number is elevated, your mouth, your gut, your metabolic health, and your visceral fat are the first places to investigate.

𝗩𝗶𝘁𝗮𝗺𝗶𝗻 𝗗
Target: 50-80 ng/mL.
Not the bare minimum of 30 your doctor accepts. Suboptimal vitamin D is linked to higher inflammation, weaker immunity, increased cardiovascular events, worse mood, and poorer outcomes across nearly every disease I treat. Supplement D3 with K2 — without K2, calcium deposits in your arteries instead of your bones.

𝗧𝗲𝘀𝘁𝗼𝘀𝘁𝗲𝗿𝗼𝗻𝗲 (𝗧𝗼𝘁𝗮𝗹 + 𝗙𝗿𝗲𝗲)
Men: optimal range 600-1000+ ng/dL total.
Declining testosterone is an independent predictor of cardiovascular death in men. It's tied to insulin resistance, arterial stiffness, visceral fat accumulation, and systemic inflammation. DHEA-S drops 10-20% every decade after 30. Tracking these isn't about vanity — it's evaluating your body's systemic resilience.

𝗕𝗹𝗼𝗼𝗱 𝗣𝗿𝗲𝘀𝘀𝘂𝗿𝗲
Target: below 120/80. Aim closer to 110/70.
Every point above optimal is cumulative arterial damage. Buy a home cuff. Measure morning and evening, seated quietly for five minutes, arm at heart level. White-coat readings in the office miss what's really happening. The smartest $40 investment in cardiac self-care.

𝗩𝗢𝟮 𝗠𝗮𝘅
Men over 40: above 40 mL/kg/min. Women over 40: above 35.
Cardiorespiratory fitness is the single strongest predictor of all-cause mortality — stronger than smoking, diabetes, or heart disease as individual risk factors. A landmark study in JAMA found that extreme fitness was associated with the lowest mortality with no upper limit of benefit. You can estimate VO2 max with a timed mile, a rower test, or a wearable. Get faster every year.

𝗡𝘂𝗺𝗯𝗲𝗿 𝗼𝗳 𝗠𝗲𝗱𝗶𝗰𝗮𝘁𝗶𝗼𝗻𝘀
Target: as few as possible.
Every medication you're on should be earning its place. I just wrote about five commonly prescribed drugs that do more harm than good with long-term use. Bring your full medication list to every appointment. Ask: "Do I still need this?" Deprescribing is one of the most powerful and underused tools in medicine.
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Thirteen numbers. Most available through cheap bloodwork and simple tests. Get them once or twice a year. Here's what I want you to understand: these numbers don't just tell you where you are. They tell you where you're heading. A fasting insulin of 8 today becomes diabetes in five years. An ApoB of 120 today becomes a heart attack in ten. An hs-CRP of 3 today means your arteries are inflamed right now — regardless of how healthy you feel. The standard annual physical checks a fraction of these. It was designed to find disease that's already there. This panel finds the disease that's coming — years before it arrives.

What gets measured gets improved. Optimize with the foundation I write about every week on this platform:
Zone 2 cardio plus resistance training 3-4 times per week. High-protein whole-food nutrition. Sleep 7-9 hours — non-negotiable. Morning sunlight. Stress management. And the targeted supplements I've covered in detail — creatine, magnesium, CoQ10, D3+K2, glycine, omega-3, psyllium husk.
The breakthroughs coming in the next decade — gene editing for cholesterol, cellular reprogramming, senolytics that clear senescent "zombie" cells driving inflammation and aging, GLP-1 drugs rewriting metabolic medicine — will be most powerful for people who've already built the metabolic foundation to receive them.

The future of medicine is personalized. But it starts with knowing your numbers today. Print this list. Book the bloodwork. Own the data. Prevention isn't passive. It's the most aggressive thing you can do for the decades ahead.

[Essentials by Nature @essentialnature]

@JayGenXer @BenMulroney https://t.co/2ftXQf5uZ0

[Jonathan Choe @choeshow]

A majority Muslim city council in Michigan voted to permanently ban the LGBTQ Pride Flag on public property.
White liberal women who welcomed refugees from Islamic countries are now wondering what happened.
Consequences of suicidal empathy coming to a leftist town near you.