Ester

Biochemist. PhD in Neuroscience 🧠🔬

[Ester @estersanchezmar]

Cositas bonitas por el microscopio: precursores de oligodendrocitos 👶y oligodendrocitos en diferenciación 🧓
#phdlife #oligodendrocyte

[William A. Wallace, Ph.D. @WilliamWallace]

Our brain isn’t just made of neurons. It runs on a whole neighborhood of cells that can either protect your mind or quietly push it toward inflammation.

This diagram reveals how astrocytes, microglia, neurons and oligodendrocytes talk to each other during stress, illness, and injury. Their conversations shape memory, mood, cognition, and long-term brain resilience.

Here is what this graphic shows in plain language:

🧠 Astrocytes act as the central switchboard
They decide whether the brain environment becomes supportive or inflammatory. When they sense danger signals, they activate NF kappa B and release molecules that influence the other cells around them. When conditions are safe, they release factors that help neurons grow and help new oligodendrocytes mature.

🔥 Microglia can protect or damage depending on the signals they receive
They can release IL 1 beta, GM CSF, and other proinflammatory signals, or they can shift to a more supportive state depending on what they detect from astrocytes and neurons.

⚡ Neurons suffer when inflammation rises
Oxidative stress, nitric oxide, and loss of metabolic support weaken them. Glutamate handling becomes impaired, which increases excitotoxic stress.

🧩 Oligodendrocytes and their precursor cells respond to what the environment tells them
Inflammatory signals slow their support for neurons, while regenerative signals encourage new myelin formation and better neuron stability.

The health of your brain depends on how these cells interact, not just on neurons alone.

doi: 10.1126/scitranslmed.adi7828

[La Revuelta @LaRevuelta_TVE]

❌Sin ciencia, no hay futuro

"Tenemos un PIB mínimo dedicado a la ciencia"
"Queremos conseguir trabajos estables"

Ya no es que se reconozca a los científicos, es que con precariedad e inseguridad laboral se pueden ver obligados a abandonar los proyectos o irse a otros países

[Ester @estersanchezmar]

Some pics of my poster presentation at #FENSforum2024. Thanks everyone for coming and discussing some of my results 🤓🧠 PS01-26AM-340

[Ester @estersanchezmar]

@LauraDLHerasG Hoy en la sesión de la mañana 😊

[Ester @estersanchezmar]

At #FENSforum2024 ☺️🧠🤓

[Ricardo J. Peraza Tello @rjperazatello]

Joya…. 🤩 (los metros del mundo)

[Conchi Lillo🧠🔬👀 @ConchiLillo]

Pues nada, otra vez a cambiar los libros de texto! Nuevo orgánulo descubierto en algas marinas: el nitroplasto, que fija nitrógeno en estos organismos ayudado por el ATP que producen las mitocondrias, gracias al consumo de los azúcares generados en los cloroplastos.

[Saab, Aiman S. @aiman_saab]

Excited to announce that our paper on activity- and potassium-mediated metabolic coupling between oligodendrocytes and axons is now published @NatureNeuro congrats to Zoe Looser, @zainabfaik, the whole team and co-authors for this achievement!
https://t.co/qVVa2ZI4yW

[Ester @estersanchezmar]

@R_Moreno_Luna Enhorabuena!! 👏

[Blanca Ochoa @Blancx8ab]

Yesterday, @estersanchezmar and I were part of the #ScienceWeek2023, explaining our research lines. It was exciting to bring neuroscience closer to all types of audience and have the opportunity to show the role of women in this field! #ZientziaAstea

[Marsicano Lab @MarsicanoLab]

First Mato/Marsicano joint lab retreat about to end! Spent almost a whole week sharing exciting science in the beautiful Basque country 🏞️ @SusanaMato13

[Dr. Pablo Barrecheguren 🧠 @pjbarrecheguren]

Como hoy es el #DíaMundialDelAlzheimer, abro el tradicional #Neurohilo para hablar de su descubrimiento, neurobiología, prevención y casos históricos:
#Neurocosas #Neurociencia #Alzheimer #Cerebro

[Ester @estersanchezmar]

@R_Moreno_Luna Tuve buen maestro 🙂

[Ester @estersanchezmar]

Cositas bonitas por el microscopio: precursores de oligodendrocitos 👶y oligodendrocitos en diferenciación 🧓
#phdlife #oligodendrocyte

[Ester @estersanchezmar]

It was a great pleasure to attend and take part in the first Severo Ochoa Conference. Learning and sharing glial/neuronal metabolic works! #ISOConference @SEBBM_es

[Marina García Macia @Juanaloca2002]

Ester Sánchez-Martin from @SusanaMato13 lab is explaining her wonderful research #ISOConference @SEBBM_es @FFarmaciaUSAL

[José Mª Adsuara @JoseMAdsuara]

Fosforilación oxidativa

Créditos: Biodecofa

[Natalia Vartan @NataliaVartan]

Hoy hace 33 años que se obtuvo la que, probablemente, es la imagen más icónica de la historia de la astronomía. The Pale Blue Dot—el punto azul palido—como la bautizó Carl Sagan, el impulsor de que se hiciera. La obtuvo la sonda Voyager 1 el 14/2/1990

📸NASA/JPL-Caltech.

[Ʌʗʜʋʗɑɼɼʘ @AchucarroGlia]

#Kromatografia laborategiaren bitartez, mezu ezkutua argitu behar dute gure minizientzialariak.

[Ester @estersanchezmar]

@SoriaFN Gracias!! Live imaging 🙂

[Ester @estersanchezmar]

La tesis también te da ratitos buenos. Mitocondrias de un oligodendrocito 😍 #oligodendrocyte #mitochondria #phdlife