EUbOPEN

Enabling and Unlocking Biology in the Open

[EUbOPEN @EUbOPEN]

Our #EUbOPEN consortium of 22 partners will work together on a 5 year 66M€ @IMI_JU
project @EUbOPEN
to generate open-access chemogenomics compounds and chemical probes! Find out more here: https://t.co/UgJ2NqRvPT #OpenScience

[EUbOPEN @EUbOPEN]

@EUbOPEN partner @AlessioCiulli, pioneers a molecule that targets a previously "undruggable" protein class! By ingeniously masking the molecule, it can enter cells paving the way for innovative disease treatments.
https://t.co/7TAR37mSIc
@IMI @UoDCeTPD

[Structural Genomics Consortium (SGC) @thesgconline]

In the last #20yearsSGC, we're thrilled to be part of the @EUbOPEN consortium, an endeavor dedicated to developing high-quality chemical tool compounds for 1,000 proteins. Over the past 3 years, our collective efforts have yielded remarkable achievements.

[Structural Genomics Consortium (SGC) @thesgconline]

The 2nd @EUbOPEN annual meeting was successfully held earlier this week. Among affiliated partners, SGC showcased a strong presence, by sharing updates on our progress toward the consortium's goal of generating chemical modulators for the entire druggable proteome.

[Target 2035 @target2035]

Register now for @target2035's upcoming webinar on February 21 and learn all you need for @XChem_DLS, a dedicated platform for crystallographic fragment screening. @Darenfearon @DiamondLightSou @KoekemoerLizbe @CmdOxford @EubOPEN https://t.co/2t3aryrwtW

[FAIRplus @FAIRplus_eu]

🙌 @EUbOPEN is fully committed to #OpenScience and aims to publish all its generated data open and fully #accessible to everyone.
Read our case study 📄 on EUbOPEN to find out our collaboration on making data #FAIR: https://t.co/wfOjySx0MS

[Structural Genomics Consortium (SGC) @thesgconline]

Don't miss your opportunity to take part in the second #CACHEChallenge! The target is the NSP13 helicase of #SARSCoV2. Submit your application to join the CACHE competition. Apply today! https://t.co/eYsw4knmVg
#DrugDiscovery #OpenScience #Target2035

[Target 2035 @target2035]

RT
@EUbOPEN #trainees #phdstudent #chemicalbiology

[Iffat @IfSumia]

Happy to share that they liked my flash talk enough to give me a prize at the #SeedpodsDay! Life pro tip, wear a baby bump as a good luck charm!

[EUbOPEN @EUbOPEN]

This Tuesday JUNE 14 10AM EDT/4PM CEST Target2035 Webinar: Towards Autonomous Bioactive Molecular Discovery! Register NOW https://t.co/3yGw0gqlWz

[Target 2035 @target2035]

cc: @EUbOPEN

[Chemical Probes Portal @Chemical_probes]

It's here: you can now download all the data on the Chemical Probes Portal! Use our new feature to download the full dataset, choose individual chemical probes or filter by protein target, target family, expert rating etc.
Find out more: https://t.co/hzXBGABjD9

[Matthew Todd @MatToddChem]

We're seeking inhibitors of #PLCzeta1 towards new, inexpensive, non-hormonal female contraceptives. You'll work with other target champions across the worldwide @thesgconline - a very strong, collaborative team funded by the Gates Foundation. #globalhealth 2/3

[Structural Genomics Consortium (SGC) @thesgconline]

Groundbreaking work from @CherylArrowsmi1, @thesgconline team @researchuoft, @PMResearch_UHN and research partners released today in @nchembio reveals MS023 induces #antitumor activity for #triplenegativebreastcancer.
Read more here: https://t.co/W9dBv6AbgO

[EUbOPEN @EUbOPEN]

Interested in a new challenge? Check out this role for a Senior Scientist and Programme Leader at @CmdOxford https://t.co/Yy0g0UtTHv

[EUbOPEN @EUbOPEN]

Register now for the next @target2035 webinar!

[Target 2035 @target2035]

This is a great webinar series! @FNucleosome also have YouTube channel https://t.co/5NwQxgWt9Q.

cc: @EUbOPEN

[EUbOPEN @EUbOPEN]

Register now for the next @target2035 webinar!

[John Litchfield @68john]

Through its participation in @IHIEurope @EUbOPEN, @Pfizer is helping to support the generation of chemical tools which may help scientists develop compounds that target proteins as specifically as possible. #PFEColleague https://t.co/ooCbCsLCpi

[Matthew Todd @MatToddChem]

Our very first @thesgconline Open Chemistry Networks meeting later today (5pm UK). Project 4, SARS-CoV-2 Nsp13 fragment project, chaired by student champ @TomMBK97. Details: https://t.co/OSJylTe2Vo All welcome. #openscience #SGC-OCN #SGCchem @target2035 #FBDD

[Centre for Medicines Discovery @CmdOxford]

The Bullock lab has a new paper in Cell Death Differ “Disease-associated KBTBD4 mutations in medulloblastoma elicit neomorphic ubiquitylation activity to promote CoREST degradation” showing how mutations change E3 ligase substrate recognition. DOI: 10.1038/s41418-022-00983-4