XChem

XChem fragment screening platform at Diamond Light Source

[XChem @XChem_DLS]

We are recruiting a PDRA to enable crystallographic fragment screening and high-throughput structural biology to support our NIH funded, open-science, antiviral drug discovery projects @asap_discovery

https://t.co/RrfN7dYPg1

Please get in touch if you have any questions.

[Lena Quambusch @LenaQuambusch]

Brought some diamonds to Diamond!💎 Its’s synchrotron time. Let’s fish 1.2 k crystals.
#science #xray #structuralbiology @DiamondLightSou @HyvonenGroup

[Frank von Delft @FrankvonDelft]

We're recruiting: Science Coordinator (Jr / Sr) to @asap_discovery in @XChem_DLS team at @DiamondLightSou. See https://t.co/v9oYhXYPzu - deadline Jan 15.
For scientists who're done postdocing, but like large collabs, coordinating, writing, outreach - ping me if any questions.

[Lizbe Koekemoer @KoekemoerLizbe]

This week I had the privilege to share my @XChem_DLS user experience as the @CmdOxford BAG PI at @ccp4_mx study weekend with lessons from @asap_discovery and @covid_moonshot. What a way to start the year.

[SDDC @SussexDDC]

The SDDC team hard at work looking for new chemical fragments! thank you to the support scientists @XChem_DLS for all the help @Diamond_MX

[Diamond Light Source @DiamondLightSou]

You can hear more about this paper, and the work done at Diamond'd @XChem_DLS and I04-1 beamlines on @BBCOxford with @Brucey1 here: https://t.co/Sz65OdpuK7

[Diamond Light Source @DiamondLightSou]

Just released in @ScienceMagazine, the @covid_moonshot Consortium, of which we are a proud member, reveals that #OpenScience is a viable route to early #DrugDiscovery, with the first-ever crowd-sourced small molecule discovery & a potent SARS-CoV-2 antiviral lead compound

[Diamond Light Source @DiamondLightSou]

Today is #WorldScienceDay - and we are celebrating just some of the ground-breaking research that happens here in the #Synchrotron

[Jonathan Grimes @jonathan_grimes]

📢 Exciting job opportunity !!

A postdoc position is available in my lab at
@OxfordStrubi
@NDMOxford
@UniofOxford
to study influenza virus transcription, genome replication, nuclear export and assembly in a stimulating lab environment.

https://t.co/vGS7hWSoBP

[rcsb pdb 💉🧬💻🔬💊🌱🧠🦠 @buildmodels]

PDB released 478 SARS-CoV-2 structures this week, including 466 mpros with inhibitors from the COVID Moonshot project. 966 have been released this year (shown), for 3826 total since the first CV19 structure was released in Feb 2020.
Explore them all at https://t.co/q3UBxbZoaF

[Frank von Delft @FrankvonDelft]

We hiring two posts to @XChem_DLS and @asap_discovery, to develop next-gen methods in progressing fragment hits to potency, fast:
* much smarter biophysics (https://t.co/WHp897ODED - closing THIS SUNDAY);
* much better informatics (https://t.co/6A2USjkm1z - closing Oct 22)

[Diamond Light Source @DiamondLightSou]

Are you attending @IUCr2023? Come and visit the Diamond Light Source & @lightsources exhibition booth, we have a #lightforscience t-shirt waiting for you!

[Diamond Light Source @DiamondLightSou]

@IUCr2023 is on! 🇦🇺 Come and talk to us about facilities, instruments, research projects, career/studentship opportunities at @DiamondLightSou and find out more about @lightsources💡

[XChem @XChem_DLS]

If you are @IUCr2023 you can come find out how XChem are using crystallographic fragment screening to enable open science discovery of new antivirals as a member of @asap_discovery at poster P0046.

[Lizbe Koekemoer @KoekemoerLizbe]

Internationale Pandemic Sciences Conference 2023: making the exceptional routine. @asap_discovery @CmdOxford @XChem_DLS @DelftAnnette

[Lizbe Koekemoer @KoekemoerLizbe]

Another Erice talk from Jasmin in the @XChem_DLS team on the EV-D68 3C protease fragment screen we did as part of @asap_discovery. Our first ASAP fragment screen is now out in the wild!

[Lizbe Koekemoer @KoekemoerLizbe]

We are rocking Erice! This time Jasmin with an @XChem_DLS poster on our @asap_discovery work done @CmdOxford and @DiamondLightSou. Go team!

[Lizbe Koekemoer @KoekemoerLizbe]

Caught in action taking a photo of the cool kids @XChem_DLS at the @asap_discovery NYC meeting. It is a privilege to work with all of you!

[XChem @XChem_DLS]

@KoekemoerLizbe @Darenfearon @asap_discovery @CmdOxford The XChem team are enjoying the week in New York talking science and strategy with our wonderful @asap_discovery colleagues and collaborators.

[Lizbe Koekemoer @KoekemoerLizbe]

@Darenfearon and I presenting to the ASAP SAB at our onsite meeting in New York.
@asap_discovery @XChem_DLS @CmdOxford