Eva Novoa

PhD at Molecular Metabolism CiMUS/IDIS

[Eva Novoa @evanovoad]

@Amaia_777 @NottmTrentUni @fruhbecklab @ClinicaNavarra Congrats!!! 😊😊😊

[Eva Novoa @evanovoad]

Hoy, en el Día de la Mujer Trabajadora, salimos en el periódico. Un orgullo compartir este logro y seguir avanzando en ciencia.
Gracias especialmente a mi compañera @ParrachoTamara por su trabajo, esfuerzo y dedicación 💜🔬
https://t.co/0dktc56bUK

[Eva Novoa @evanovoad]

@mar_quinones_es @cimususc Mil gracias Mar!! 😊😊

[Eva Novoa @evanovoad]

We are back!! I'm excited to share our new paper from @RubenNogueiras lab at @cimususc , where we identified the key role of PCK1 in liver fibrosis progression. Key findings below...👇

[Cell Metabolism @Cell_Metabolism]

New! Online now: Lack of PCK1 in hepatic stellate cells causes liver fibrosis by fueling tricarboxylic acid cycle and increasing glycolysis https://t.co/Wm3XJB4xnV

[Eva Novoa @evanovoad]

Finally, this work wouldn't have been possible without our entire lab team and collaborators, but special thanks to @ParrachoTamara and @ChusaGzlzRellan for driving this project to success! 🔬

[Eva Novoa @evanovoad]

So, PCK1 protects the liver from scarring by keeping fibrogenic cells in a quiescent state. When PCK1 is reduced, these cells undergo metabolic reprogramming characterized by increased glycolysis, become aberrantly activated, and promote liver fibrosis in mice.

[Eva Novoa @evanovoad]

@auroradevea Enhorabuena! Merecidísimo 😊

[Eva Novoa @evanovoad]

@daveyboyhod @RubenNogueiras "That's really intriguing! Sometimes those unexpected findings are the most valuable- I’m sure it’ll be a great contribution to the conversation about GLP1R in the liver.

[Eva Novoa @evanovoad]

I'm excited to share the findings from our recent study from @RubenNogueiras lab, where we investigated whether GLP-1 and GIP agonists have direct actions on human hepatocytes and hepatic stellate cells (HSCs)... Here is a brief summary of the newest findings...👇

[Eva Novoa @evanovoad]

🔍 For more details, check out the full article here: https://t.co/9a92zsWOpu

[Eva Novoa @evanovoad]

This work wouldn’t have been possible without the entire lab team, but I especially want to thank @CabaleiroAlba and Natalia for making this project a success. 🙌