Frederik (Frits) Deiman

Dutch cardiovascular researcher interested in genetic cardiomyopathies and precision medicine.

[Frederik (Frits) Deiman @F_Deiman]

Proud to see our work on phospholamban (PLN) cardiomyopathy featured on the cover of Signal Transduction and Targeted Therapy.

[Signal Transduction and Targeted Therapy (STTT) @sigtrans_sttt]

Researchers use #Phosphoproteomics to define disease-specific pathways in phospholamban #Cardiomyopathy and show that #RNAtherapy can reverse key molecular defects associated with #CardiacDysfunction. @univgroningen
#STTT #OpenAccess: https://t.co/KCFXIpmYab

[European Society of Cardiology Journals @ESC_Journals]

Plasma proteomics stratification of phospholamban R14del carriers reveals subgroups, enabling identification of those at high-risk & better understanding of disease variability
https://t.co/v9xE4bnVQ9

@CVR_TomaszGuzik @glenpyle @DrMikeDrozd @Sarah_KBrown #CardiovascularResearch

[Frederik (Frits) Deiman @F_Deiman]

Now published in @sigtrans_sttt; RNA therapy can directly target the molecular mechanisms underlying heart failure.

Our research shows that PLN-targeted RNA therapy can reverse molecular abnormalities and reduce protein aggregation in PLN cardiomyopathy.
https://t.co/tPPGPeN2oJ

[Frederik (Frits) Deiman @F_Deiman]

What drives phospholamban cardiomyopathy? In an interview with De Cardioloog, I discuss emerging insights into disease mechanisms and how understanding biology can pave the way toward targeted therapies and precision medicine.

https://t.co/72RTgLgCkD

[Frederik (Frits) Deiman @F_Deiman]

Representing @CardiologyUmcg at #HeartFailure26

#HeartFailure #HFA_ESC #HFA

[European Society of Cardiology @escardio]

Celebrating young talent at #HeartFailure26 🌟

Congratulations to this year’s Young Investigator Award winners for their outstanding contributions to heart failure research and clinical practice:
🏆 Aamir Wahhab – Clinical Cardiology
🏆 Frederik Ernst Deiman – Basic Science
🏆 William Baker – Nursing and Allied Professions Congratulations also go to🏆 Anne Koppelaar for the Clinical Case Award

#HFA_ESC #HeartFailure #Cardiology @HFA_President

[Frederik (Frits) Deiman @F_Deiman]

#ESCTV #HFA @escardio #HeartFailure26

https://t.co/xArejcUvJ5

[Frederik (Frits) Deiman @F_Deiman]

#HeartFailure25

[Frederik (Frits) Deiman @F_Deiman]

#EHRA25

[Frederik (Frits) Deiman @F_Deiman]

#ESCCongress24

[Frederik (Frits) Deiman @F_Deiman]

A throwback to #ISHR_ES24

[Frederik (Frits) Deiman @F_Deiman]

A look back at #HeartFailure23

[Frederik (Frits) Deiman @F_Deiman]

One of the biggest challenges in genetic heart failure is predicting who will develop disease.

We explored a pre-clinical phase in carriers of a pathogenic variant (PLN R14del), where the heart appears normal, but molecular changes are already unfolding.

https://t.co/EvP8CBgqIY

[Santos' Lab @SantosLab_UMCG]

🎉 Our first collaborative paper of 2026 is out!🫀
We identify AMP as a novel activator of OPLAH, a key enzyme linked to oxidative stress in heart failure, and enable its intracellular delivery using engineered polymeric nanoparticles.Congrats to all!👏
🔗 https://t.co/AKmD6PrCHX

[UMCG Cardiology Research Institute @CardiologyUmcg]

At the #HFAwintermeeting, @CardiologyUmcg is represented by six PhD/post-docs who shared their own data with the research community during the poster session @LauraMeems @BomerNils @SuzanneVoorrips

[Jozine ter Maaten @jozinetm]

@CardiologyUmcg taking over #HeartFailure2023
Such a privilege to be a part of this fantastic group of #heartfailure researchers and physicians @iebeldhuis @LauraMeems @kevin_damman

[UMCG Cardiology Research Institute @CardiologyUmcg]

Working from home during the corona pandemic; take a look at our home offices in this news item on our website!
https://t.co/NRWmmg5T7S

[Frederik (Frits) Deiman @F_Deiman]

We believe RNA Therapeutics will play an important role in the management of #HeartFailure in the future.

Check out our translational perspective in Journal of Cardiovascular Translational Research: https://t.co/879WCbKZpv

#Cardiology #cardiotwitter #Cardio

[UMCG Cardiology Research Institute @CardiologyUmcg]

Precision medicine for targeting PLN R14del. A beautiful review by Frits Deiman. Let's see what the future will bring us! #heartfailure @SpringerNature