Laura Meems

MD PhD🇳🇱|👩‍⚕️Cardiology| 👩‍🏫 Postdoc Fellow in Translational Cardiology focusing on Sex differences in Heart Failure, HFpEF + Cardio-Obesity. Glutenfree.

[Laura Meems @LauraMeems]

@DrDamluji @NEJM @AHAScience Wonderful summary of a very important trial. I believe inverting modification will represent a novel treatment pillar in HF(pEF)! One of the main questions to be answered: will we use it as chronic therapy (such as traditional HF drugs) or as burst therapy (such as diuretics)?!

[Laura Meems @LauraMeems]

This morning during a combined #AHA #ACC and #ESC session at #ESC2024 I advocated for a new subspecialty of “cardiobesity”. What do you think? Yes ✅ or no 🛑?! @HanCardiomd @escardio @matthewmylee

[Michelle Rosenfeld @MichelleR_Heart]

❗️At #ESCCongress now: “We may have to conclude BMI is outdated; we need other factors” says @laurameems. She suggests new subspecialty: “cardiobesity” #obesity #CardioTwitter

[Laura Meems @LauraMeems]

Today I gave a talk at #ESC2024 about #glp1ra in #HFpEF. A fully packed room and 12 minutes to talk about new insights.

What you missed?
✅ obesity is important, also for cardiologists
✅ glp1RAs are cardioprotective
✅ MoA studies are needed
@escardio @HFA_President

[Laura Meems @LauraMeems]

@matthewmylee Great work Matt!! Also very important to differentiate the effects of semaglutide. Will be important how to position this drug and decide who to prescribe and it’s duration (although studies suggest that even short time therapy may have long-term benefits on atherosclerosis!)

[Laura Meems @LauraMeems]

@MaartenVHemelen @VerwerftJan Very relevant question since cardio-obesity is a real problem!

In our clinical practice, we start with a general work-up with NTproBNP, ECG and echocardiography.
Next CPET or iCPET can be performed to assess intracradiac pressures.
Not sure? Discuss with HFpEF expert center!

[Laura Meems @LauraMeems]

@HanCardiomd @escardio @ESC_Journals @ShelleyZieroth @MarcoMetra @AndrewJSauer @RyanTedfordMD @susannaprice @m4ggiesimpson @ESC_President @EJHFEiC @DrRyanPDaly @ACVCPresident @WilfriedMullens @pabeda1 @mmamas1973 @docbhardwaj @rafavidalperez Any information on what to do with an obese patient in CS? A role for ECMO there, or just pray and wait..?

[Laura Meems @LauraMeems]

@VerwerftJan @TaubenA @hvanspall Very interesting study!

Was there a difference in HF subtypes (makes more HFrEF, females more HFpEF?) that could explain the observed differences?

[Laura Meems @LauraMeems]

#hartfalen in de spotlight tijdens #nationalehartfalenweek!

In een interview met @hartinshape en @vrouwenhartspreekt sprak ik over hartfalen, man-vrouw verschillen én onze #hfpef poli in @umcg @CardiologyUmcg @WestenbrinkDaan

Benieuwd naar meer?
https://t.co/LsEv1M2sfM

[Laura Meems @LauraMeems]

@salonfahigsujet Wat fijn dat de publiekslezing je meer informatie heeft gebracht! In NL zijn een paar ziekenhuizen zeer actief in opsporen en behandelen van onzichtbaar #hartfalen (#HFpEF). Naast @umcg ook Maastricht en A’dam (VU). Toch is er nog veel werk te doen, dus wij strijden door!

[Laura Meems @LauraMeems]

Ben jij…

✅ een (bijna) arts met ambitie onzichtbaar hartfalen gemakkelijker op te sporen
✅ geïnteresseerd in de nieuwste MRI technieken en cardiologie
✅ een zelfstandige teamspeler die niet bang is om te innoveren

Solliciteer dan nu! #phdstudent

https://t.co/e1sLeOj5rM

[Cardiology USZ @CardioZurich]

📺Esteemed #PCHF Alumni 2022/2023,
Congratulations! Your graduation marks the start of your journey as a member of our growing network dedicated to modern #HeartFailure management around the 🌍🌏🌎 https://t.co/rH4TXGZeWr

🙏🏽@JasaityteRuta @david_cm_ @Massimi78530343 @LauraMeems @UZH_en @escardio @HFA_President #HFA_ESC @ESC_President @EJHFEiC @MarcoMetra @WilfriedMullens @ZOLziekenhuis @Uhasselt @FinnGustafsson @CardioZurich @Unispital_USZ @CTECresearch @Steph_Achenbach @MG_Crespo_Leiro @BarandiaranHF @javiercastrodz @ZOLziekenhuis @Uhasselt @GiuseppeGalati_ #HF @_anmco @clara_clarais @GMCRosano @secardiologia @maria_viu @MajaCikes @lamcardio @ShehabAnwer @rmanka_ @Alkadhi_rad @andgiannopmd @HartcentrumH @JessaZiekenhuis @UZH_dsi @GraduateCampus @DQBM_uzh @UZH_ch

[Maja Cikes @MajaCikes]

#PCHF Zürich continues to set standards and lead #HeartFailure education in Europe, with a global reach. Congratulations to all of the graduates, faculty and leadership of the course - 5 generations raised, more to come! Honored to be part of this stellar family! 🎓💥🫀📚

[Laura Meems @LauraMeems]

Thank you prof. Marc Pfeffer for your words of wisdom:

“Be part of something, you cannot do it by yourself!”

And that’s exactly what #PCHF has been: a 2 years course, and a life-long friendship with likeminded HFenthusiasts! #heartfailure #graduation
@CardioZurich
@escardio

[Laura Meems @LauraMeems]

PCHF module 8: the final module!

Looking forward to learn from the giants one more time.
Fun, heart failure facts and a final graduation ceremony on Saturday.

Let’s get started! @CardioZurich @drsoli4030 @mjschuuring @BarandiaranHF

[Laura Meems @LauraMeems]

@HanCardiomd @pfizer @JamalRanaMD @SJGreene_md @mvaduganathan @ESC_Journals @TCTMD @mmamas1973 @DrMarthaGulati @pabeda1 @ErinMichos @AHajduczok I’m wondering about it’s CVprotective effects. Previously, <10% weight loss (drugs or lifestyle) did not do the trick. Nevertheless, targeting GLP1-RA may have CVprotective effect regardless of weight loss. What about this one? #cardioTwitter #cardioobesity @matthewmylee

[Laura Meems @LauraMeems]

Check out this latest study performed at our lab @CardiologyUmcg ! Great example of translational research that holds potential to improve life of PLN-R14del cardiomyopathy patients @HanCardiomd @rudolf_debar

[Herman Sillje @HSillje]

Exciting breakthroughs in PLN-R14del cardiomyopathy! Our latest research has just been published in Circulation Research.

https://t.co/WpfhB0rLjL

[Laura Meems @LauraMeems]

@VerwerftJan @FH_Verbrugge @JasaityteRuta @JessaZiekenhuis @HartcentrumH @uhasselt @UZBrussel @VUBrussel @sarahhoed Yes, I fully agree @VerwerftJan @FH_Verbrugge. In some papers AS is rendered to as “secondary” HFpEF. Still important to recognize since severe AS deserves different treatment strategy!

[Eric Topol @EricTopol]

Just published @NatureMedicine
Randomized trial of tirzepatide (Mounjaro) vs placebo *after* 12 weeks of intensive lifestyle intervention and >5% weight loss
https://t.co/zfbMsgK1sF
At 72 weeks, Placebo group gained 2.5% weight back; GLP-1 drug lost additional 18.4% body weight

[Laura Meems @LauraMeems]

@peripheryk18191 @FZores Great question!

NYHA I patiënt so I wouldn’t add anything.
Worsening HF signs and complaints? Add SGLT2i in euvolemic patients and diuretics followed by MRA in volume overloaded pts..

Main question remains: WHY #heartfailure? Etiology is key 🔑

@AndreasGevaert @HanCardiomd

[Laura Meems @LauraMeems]

@CardioZurich Module 7 acute #heartfailure was a blast!

Some wise words from Prof. @FRuschitzka himself: happiness is the delta between where you are and where you want to be. If the gap is not too wide, you’re doing pretty well!
#medtwitter #cardiology