Indels allow antiviral proteins to evolve functional novelty inaccessible by missense mutations by @Jtenthorey and colleagues
https://t.co/KzxbkfFc1T
Highlight from @CellGenomics
Excited to share our latest paper, out today @CellCellPress. We found that large pieces of the human genome can transfer between cells upon direct contact, endowing recipient cells with heritable phenotypic changes. (1/7)
https://t.co/SbshGhofN0
Congratulations to Febri @febrigunawan48 on earning a PhD from Pitt Med! One more paper has just been accepted by the Journal of Virology as well; a tremendous achievement. So proud of you, and wishing you all the best on your next journey in Reuben Harris’s lab in San Antonio!
🧬 New paper out in @Nature! We used CRISPR to selectively kill cancer cells based on a single-letter mutation in their RNA. The story I want to highlight: KRAS — one of the most notorious drivers of human cancer. A short thread on what we found 🧵
Students, postdocs, and faculty: Exciting funding opportunities are on the horizon from the Howard Hughes Medical Institute (HHMI).
This fall, HHMI will launch programs supporting:
- Faculty with up to $10M over 10 years, which includes salary, benefits, and research support.
- Postdocs with up to 2 years of salary and research support, facilitating a transition to independent funding.
- PhD students with a $50,000 annual stipend for up to 3 years, along with additional institutional and postdoctoral funding opportunities.
More details: https://t.co/abruWKC1SI
If you're a senior researcher (i.e., associate professor or more senior), and you'd consider moving to the University of Toronto to take up a Canada Impact+ Research Chair (1 million/year in funding), email me. Discretion guaranteed.
++Please share to help me spread the word!++
A preprint‼️that's bound to ruffle some 🪶 "Widespread DNA off-targeting confounds studies of RNA chromatin occupancy" led by our @MicahGoldrich and Louis Delhaye from @pieter_mestdagh. TL;DR we show that many of lncRNA chromatin occupancy maps are flawed🧵https://t.co/eCq6nORxQm
A groundbreaking paper by @younis_sh1 et al. @stanfordimmuno provides an answer to the long-standing question about how EBV infections are linked to lupus. A short thread to explain the key findings. (1/)
https://t.co/dUpz19IjEv
🦖 Something HUGE just hatched.
Plasmidsaurus now offers RNA sequencing for gene expression analysis with:
• As fast as 3 day turnaround
• $50/sample for academia, $80 for industry
• Up to ~10M unique transcript 3’ end reads per sample
• Interactive results that let you explore changes in genes and pathways
Explore Plasmidsaurus RNA-Seq today.
Congratulations #Maldives 🇲🇻 for achieving ‘triple elimination’ of mother-to-child transmission of HIV, syphilis and hepatitis B — becoming the first country in the world 🌏 to reach this remarkable milestone!
This historic success was possible because of
✔️ an integrated and comprehensive approach to maternal and child health
✔️ universal health coverage, supported by strong policies and investment of over 10% of GDP in health
✔️ strong partnerships between government, private health providers, civil society, and international partners
#tripleelimination #WHOSEARO #publichealth
Legend David Baltimore died yesterday. He understood the way things should work: "the real contribution of @MIT is that it doesn't take itself too seriously. It takes ideas seriously, but the people are relatively informal. They are not self-aggrandizing the way academics can be.
So grateful that my lab is celebrating its 25th anniversary next week! Super lucky to work with such an inspiring team that made this possible 🙏🏼🙏🏼🙏🏼
Join us as we celebrate our 25th anniversary with a special symposium 🤗 @YaleMed
Another month, another insane protein design paper from the Baker Lab.
This time: Designing binders for intrinsically disordered regions, a common & important component of proteins we care about, with the help of a diffusion model
In @Nature last week